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Oudin Åström, Daniel
Alternative names
Publications (10 of 40) Show all publications
Bjursten, H., Oudin Åström, D. & Zindovic, I. (2023). Reply to Schäfers [Letter to the editor]. Interdisciplinary cardiovascular and thoracic surgery, 36(5), Article ID ivad060.
Open this publication in new window or tab >>Reply to Schäfers
2023 (English)In: Interdisciplinary cardiovascular and thoracic surgery, ISSN 2753-670X, Vol. 36, no 5, article id ivad060Article in journal, Letter (Other academic) Published
Place, publisher, year, edition, pages
Oxford University Press, 2023
Keywords
Aortic dissection, Lunar phases
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:umu:diva-218953 (URN)10.1093/icvts/ivad060 (DOI)000987882900001 ()37144955 (PubMedID)2-s2.0-85182348778 (Scopus ID)
Available from: 2024-01-03 Created: 2024-01-03 Last updated: 2024-01-22Bibliographically approved
Olstrup, H., Flanagan, E., Persson, J.-O., Rittner, R., Krage Carlsen, H., Stockfelt, L., . . . Oudin, A. (2023). The long-term mortality effects associated with exposure to particles and nox in the Malmö diet and cancer cohort. Toxics, 11(11), Article ID 913.
Open this publication in new window or tab >>The long-term mortality effects associated with exposure to particles and nox in the Malmö diet and cancer cohort
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2023 (English)In: Toxics, E-ISSN 2305-6304, Vol. 11, no 11, article id 913Article in journal (Refereed) Published
Abstract [en]

In this study, the long-term mortality effects associated with exposure to PM10 (particles with an aerodynamic diameter smaller than or equal to 10 µm), PM2.5 (particles with an aerodynamic diameter smaller than or equal to 2.5 µm), BC (black carbon), and NOx (nitrogen oxides) were analyzed in a cohort in southern Sweden during the period from 1991 to 2016. Participants (those residing in Malmö, Sweden, born between 1923 and 1950) were randomly recruited from 1991 to 1996. At enrollment, 30,438 participants underwent a health screening, which consisted of questionnaires about lifestyle and diet, a clinical examination, and blood sampling. Mortality data were retrieved from the Swedish National Cause of Death Register. The modeled concentrations of PM10, PM2.5, BC, and NOx at the cohort participants’ home addresses were used to assess air pollution exposure. Cox proportional hazard models were used to estimate the associations between long-term exposure to PM10, PM2.5, BC, and NOx and the time until death among the participants during the period from 1991 to 2016. The hazard ratios (HRs) associated with an interquartile range (IQR) increase in each air pollutant were calculated based on the exposure lag windows of the same year (lag0), 1–5 years (lag1–5), and 6–10 years (lag6–10). Three models were used with varying adjustments for possible confounders including both single-pollutant estimates and two-pollutant estimates. With adjustments for all covariates, the HRs for PM10, PM2.5, BC, and NOx in the single-pollutant models at lag1–5 were 1.06 (95% CI: 1.02–1.11), 1.01 (95% CI: 0.95–1.08), 1.07 (95% CI: 1.04–1.11), and 1.11 (95% CI: 1.07–1.16) per IQR increase, respectively. The HRs, in most cases, decreased with the inclusion of a larger number of covariates in the models. The most robust associations were shown for NOx, with statistically significant positive HRs in all the models. An overall conclusion is that road traffic-related pollutants had a significant association with mortality in the cohort.

Place, publisher, year, edition, pages
MDPI, 2023
Keywords
air pollution, Cox regression, hazard ratio, long-term exposure, nitrogen oxides, particles, proportional hazard
National Category
Occupational Health and Environmental Health
Identifiers
urn:nbn:se:umu:diva-217980 (URN)10.3390/toxics11110913 (DOI)001114628400001 ()37999565 (PubMedID)2-s2.0-85178269924 (Scopus ID)
Funder
Swedish Research Council Formas, 2017-00898EU, Horizon 2020, 814978Swedish Research Council Formas, 2016–00993
Available from: 2023-12-14 Created: 2023-12-14 Last updated: 2023-12-15Bibliographically approved
Muhsin, H. A., Steingrimsson, S., Oudin, A., Oudin Åström, D. & Carlsen, H. K. (2022). Air pollution and increased number of psychiatric emergency room visits: A case-crossover study for identifying susceptible groups. Environmental Research, 204, Article ID 112001.
Open this publication in new window or tab >>Air pollution and increased number of psychiatric emergency room visits: A case-crossover study for identifying susceptible groups
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2022 (English)In: Environmental Research, ISSN 0013-9351, E-ISSN 1096-0953, Vol. 204, article id 112001Article in journal (Refereed) Published
Abstract [en]

Background: Ambient particulate matter is a leading risk factor for disease globally. Particulate matter 10 (PM10) and particulate matter 2.5 (PM2.5) are derived from different sources, including operating motor vehicles as well as from industrial activities. In this study we investigate the association between increased concentrations of PM and total daily visits to the psychiatric emergency unit (PEV). Further, the aim is to identify specific risk groups who are more susceptible to the effects of air pollution exposure by studying sex, age, ongoing psychiatric follow-up and diagnoses of depression/anxiety or substance use.

Material and methods: The sample was comprised of data from 2740 days to 81 548 PEVs at Sahlgrenska University Hospital in Gothenburg and daily mean concentrations of PM10 and PM2.5. A time-stratified case-crossover design was used to analyse associations between air pollution and PEVs.

Results: Mean number of daily PEVs were 35 and sex distribution was even. PM exposure was associated with total PEV at lag 0 (the same day), by RR 1.016 (95% confidence interval [CI] 1.004–1.028) and RR 1.020 (95%CI 1.003–1.038) per 10 μg/m3 increase in PM10 and PM2.5, respectively. In females, PEV were increased at lag 0 and lag 1, and in males at lag 1 and lag 2. In the age-stratified analysis, PEVs significantly increased following PM exposure amongst individuals aged 35–65 years by lag 0–2 and in individuals who had contact with outpatient care at lag 0 to lag 1. There were no associations between air pollution and PEVs for any specific diagnostic group evaluated (amongst depression, anxiety and substance use disorder).

Conclusions: The results indicate that acute exposure to PM10 and PM2.5 may trigger acute worsening in mental health in both males and females, especially among 35–65 year old individuals. However, in subgroups of the most common psychiatric diagnoses, we did not observe statistically significant associations with PM exposure.

Place, publisher, year, edition, pages
Elsevier, 2022
Keywords
Air pollution, Depression, Mental health, Risk factors, Substance abuse
National Category
Occupational Health and Environmental Health Psychiatry
Identifiers
urn:nbn:se:umu:diva-191444 (URN)10.1016/j.envres.2021.112001 (DOI)000704698600004 ()34499892 (PubMedID)2-s2.0-85122488615 (Scopus ID)
Available from: 2022-01-17 Created: 2022-01-17 Last updated: 2023-03-24Bibliographically approved
Oudin, A., Bjursten, H., Oudin Åström, D., Nozohoor, S., Ahmad, K., Tang, M., . . . Zindovic, I. (2022). Impact of national holidays and weekends on incidence of acute type A aortic dissection repair. Scientific Reports, 12(1), Article ID 20552.
Open this publication in new window or tab >>Impact of national holidays and weekends on incidence of acute type A aortic dissection repair
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2022 (English)In: Scientific Reports, E-ISSN 2045-2322, Vol. 12, no 1, article id 20552Article in journal (Refereed) Published
Abstract [en]

Previous studies have demonstrated that environmental and temporal factors may affect the incidence of acute type A aortic dissection (ATAAD). Here, we aimed to investigate the hypothesis that national holidays and weekends influence the incidence of surgery for ATAAD. For the period 1st of January 2005 until 31st of December 2019, we investigated a hypothesised effect of (country-specific) national holidays and weekends on the frequency of 2995 surgical repairs for ATAAD at 10 Nordic cities included in the Nordic Consortium for Acute Type A Aortic Dissection (NORCAAD) collaboration. Compared to other days, the number of ATAAD repairs were 29% (RR 0.71; 95% CI 0.54–0.94) lower on national holidays and 26% (RR 0.74; 95% CI 0.68–0.82) lower on weekends. As day of week patterns of symptom duration were assessed and the primary analyses were adjusted for period of year, our findings suggest that the reduced surgical incidence on national holidays and weekends does not seem to correspond to seasonal effects or surgery being delayed and performed on regular working days.

Place, publisher, year, edition, pages
Nature Publishing Group, 2022
National Category
Cardiac and Cardiovascular Systems
Research subject
Cardiology
Identifiers
urn:nbn:se:umu:diva-201578 (URN)10.1038/s41598-022-25076-7 (DOI)000955946400025 ()36446905 (PubMedID)2-s2.0-85142884849 (Scopus ID)
Available from: 2022-12-13 Created: 2022-12-13 Last updated: 2023-09-05Bibliographically approved
Bjursten, H., Oudin Åström, D., Nozohoor, S., Ahmad, K., Tang, M., Bjurbom, M., . . . Zindovic, I. (2022). Once after a full moon: acute type A aortic dissection and lunar phases. Interactive Cardiovascular and Thoracic Surgery, 34(1), 105-110
Open this publication in new window or tab >>Once after a full moon: acute type A aortic dissection and lunar phases
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2022 (English)In: Interactive Cardiovascular and Thoracic Surgery, ISSN 1569-9293, E-ISSN 1569-9285, Vol. 34, no 1, p. 105-110Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: Acute type A aortic dissection (ATAAD) is a rare but severe condition, routinely treated with emergent cardiac surgery. Many surgeons have the notion that patients with ATAAD tend to come in clusters, but no studies have examined these observations. This investigation was undertaken to study the potential association between the lunar cycle and the incidence of ATAAD.

METHODS: We collected information on 2995 patients who underwent ATAAD surgery at centres from the Nordic Consortium for Acute Type A Aortic Dissection collaboration. We cross-referenced the time of surgery with lunar phase using a case-crossover design with 2 different definitions of full moon (>99% illumination and the 7-day full moon period).

RESULTS: The period when the moon was illuminated the most (99% definition) did not show any significant increase in incidence for ATAAD surgery. However, when the full moon period was compared with all other moon phases, it yielded a relative risk of 1.08 [95% confidence interval (CI) 1.00-1.17, P = 0.057] and, compared to waxing moon, only the relative risk was 1.11 (95% CI 1.01-1.23, P = 0.027). The peak incidence came 4-6 days after the moon was fully illuminated.

CONCLUSIONS: This study found an overrepresentation of surgery for ATAAD during the full moon phase. The explanation for this is not known, but we speculate that sleep deprivation during full moon leads to a temporary increase in blood pressure, which in turn could trigger rupture of the aortic wall. While this finding is interesting, it needs to be corroborated and the clinical implications are debateable.

Place, publisher, year, edition, pages
Abbaye de Maredsous, 2022
Keywords
Dissection of the aorta, Moon
National Category
Cardiac and Cardiovascular Systems Surgery
Identifiers
urn:nbn:se:umu:diva-192158 (URN)10.1093/icvts/ivab220 (DOI)000743990900015 ()34999801 (PubMedID)2-s2.0-85123459859 (Scopus ID)
Funder
Region Skåne
Available from: 2022-02-04 Created: 2022-02-04 Last updated: 2022-02-04Bibliographically approved
Dahal, U., Veber, T., Oudin Åström, D., Tamm, T., Albreht, L., Teinemaa, E., . . . Orru, H. (2022). Perinatal Health Inequalities in the Industrial Region of Estonia: A Birth Registry-Based Study. International Journal of Environmental Research and Public Health, 19(18), Article ID 11559.
Open this publication in new window or tab >>Perinatal Health Inequalities in the Industrial Region of Estonia: A Birth Registry-Based Study
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2022 (English)In: International Journal of Environmental Research and Public Health, ISSN 1661-7827, E-ISSN 1660-4601, Vol. 19, no 18, article id 11559Article in journal (Refereed) Published
Abstract [en]

Despite the increasing number of studies on industrially contaminated sites (ICS) and their health effects, there are very few studies on perinatal health outcomes in ICSs. In the present study, we examined the perinatal health inequalities by comparing adverse birth outcomes (ABOs) in the oil shale industry region of Ida-Viru County in Estonia with national-level figures and investigated the effects of maternal environmental and sociodemographic factors. Based on the 208,313 birth records from 2004–2018, Ida-Viru ICS has a birth weight 124.5 g lower than the average of 3544 g in Estonia. A higher prevalence of preterm birth (4.3%) and low birth weight (4.8%) in Ida-Viru ICS is found compared to 3.3% on both indicators at the national level. Multiple logistic regression analysis shows the statistically significant association of ABOs with fine particle (PM2.5) air pollution, mother’s ethnicity, and education throughout Estonia. However, in Ida-Viru ICS, the ABOs odds are remarkably higher in these characteristics except for the mother’s ethnicity. Furthermore, the ABOs are associated with the residential proximity to ICS. Thus, the Ida-Viru ICS has unequally higher odds of adverse perinatal health across the environmental and sociodemographic factors. In addition to reducing the air pollutants, policy actions on social disparities are vital to address the country’s unjustly higher perinatal health inequalities, especially in the Ida-Viru ICS.

Place, publisher, year, edition, pages
MDPI, 2022
Keywords
adverse birth outcomes, air pollution, industrially contaminated sites, inequality, low birth weight, preterm birth, socioeconomic status
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:umu:diva-200073 (URN)10.3390/ijerph191811559 (DOI)000856384400001 ()36141830 (PubMedID)2-s2.0-85138816586 (Scopus ID)
Funder
EU, Horizon 2020, 956780
Available from: 2022-10-10 Created: 2022-10-10 Last updated: 2022-10-10Bibliographically approved
Balidemaj, F., Flanagan, E., Malmqvist, E., Rittner, R., Källén, K., Oudin Åström, D. & Oudin, A. (2022). Prenatal Exposure to Locally Emitted Air Pollutants Is Associated with Birth Weight: An Administrative Cohort Study from Southern Sweden. Toxics, 10(7), Article ID 366.
Open this publication in new window or tab >>Prenatal Exposure to Locally Emitted Air Pollutants Is Associated with Birth Weight: An Administrative Cohort Study from Southern Sweden
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2022 (English)In: Toxics, E-ISSN 2305-6304, Vol. 10, no 7, article id 366Article in journal (Refereed) Published
Abstract [en]

While prenatal exposure to ambient air pollution has been shown to be associated with reduced birth weight, there is substantial heterogeneity across studies, and few epidemiological studies have utilized source-specific exposure data. The aim of the present study was, therefore, to investigate the associations between local, source-specific exposure to fine particulate matter (PM2.5) during pregnancy and birth weight. An administrative cohort comprising 40,245 singleton births from 2000 to 2009 in Scania, Sweden, was combined with data on relevant covariates. Investigated sources of PM2.5 included all local sources together as well as tailpipe exhaust, vehicle wear-and-tear, and small-scale residential heating separately. The relationships between these exposures, rep-resented as interquartile range (IQR) increases, and birth weight (continuous) and low birth weight (LBW; <2500 g) were analyzed in crude and adjusted models. Each local PM2.5 source investigated was associated with reduced birth weight; average decreases varied by source (12–34 g). Only small-scale residential heating was clearly associated with LBW (adjusted odds ratio: 1.14 (95% confidence interval: 1.04–1.26) per IQR increase). These results add to existing evidence that prenatal exposure to ambient air pollution disrupts fetal growth and suggest that PM2.5 from both vehicles and small-scale residential heating may reduce birth weight.

Place, publisher, year, edition, pages
MDPI, 2022
Keywords
ambient air pollution, birth weight, fine particulate matter, local air pollution, low birth weight, residential burning, source-specific exposure, traffic-related air pollution, wood-smoke
National Category
Occupational Health and Environmental Health
Identifiers
urn:nbn:se:umu:diva-198181 (URN)10.3390/toxics10070366 (DOI)000831411400001 ()2-s2.0-85133637831 (Scopus ID)
Funder
Swedish Research Council Formas, 2017-00898
Available from: 2022-07-19 Created: 2022-07-19 Last updated: 2023-09-05Bibliographically approved
Oudin Åström, D., Bjursten, H., Oudin, A., Nozohoor, S., Ahmad, K., Tang, M., . . . Zindovic, I. (2022). Temperature effects on incidence of surgery for acute type A aortic dissection in the Nordics. Global Health Action, 15(1), Article ID 2139340.
Open this publication in new window or tab >>Temperature effects on incidence of surgery for acute type A aortic dissection in the Nordics
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2022 (English)In: Global Health Action, ISSN 1654-9716, E-ISSN 1654-9880, Vol. 15, no 1, article id 2139340Article in journal (Refereed) Published
Abstract [en]

We aimed to investigate a hypothesised association between daily mean temperature and the risk of surgery for acute type A aortic dissection (ATAAD). For the period of 1 January 2005 until 31 December 2019, we collected daily data on mean temperatures and date of 2995 operations for ATAAD at 10 Nordic cities included in the Nordic Consortium for Acute Type A Aortic Dissection (NORCAAD) collaboration. Using a two-stage time-series approach, we investigated the association between hot and cold temperatures relative to the optimal temperature and the rate of ATAAD repair in the selected cities. The relative risks (RRs) of cold temperatures (≤−5°C) and hot temperatures (≥21°C) compared to optimal temperature were 1.47 (95% CI: 0.72–2.99) and 1.43 (95% CI: 0.67–3.08), respectively. In line with previous studies, we observed increased risk at cold and hot temperatures. However, the observed associations were not statistically significant, thus only providing weak evidence of an association.

Place, publisher, year, edition, pages
Taylor & Francis, 2022
Keywords
acute type A aortic dissection, cold, Heat, muli-centre study, temperature
National Category
Cardiac and Cardiovascular Systems
Identifiers
urn:nbn:se:umu:diva-201237 (URN)10.1080/16549716.2022.2139340 (DOI)000879945100001 ()36345977 (PubMedID)2-s2.0-85141749838 (Scopus ID)
Available from: 2022-12-01 Created: 2022-12-01 Last updated: 2022-12-01Bibliographically approved
Kriit, H. K., Forsberg, B., Oudin Åström, D. & Oudin, A. (2021). Annual dementia incidence and monetary burden attributable to fine particulate matter (PM2.5) exposure in Sweden. Environmental Health, 20(1), Article ID 65.
Open this publication in new window or tab >>Annual dementia incidence and monetary burden attributable to fine particulate matter (PM2.5) exposure in Sweden
2021 (English)In: Environmental Health, E-ISSN 1476-069X, Vol. 20, no 1, article id 65Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Alzheimer's disease (AD) and other dementias currently represent the fifth most common cause of death in the world, according to the World Health Organization, with a projected future increase as the proportion of the elderly in the population is growing. Air pollution has emerged as a plausible risk factor for AD, but studies estimating dementia cases attributable to exposure to fine particulate matter (PM2.5) air pollution and resulting monetary estimates are lacking.

METHODS: We used data on average population-weighted exposure to ambient PM2.5 for the entire population of Sweden above 30 years of age. To estimate the annual number of dementia cases attributable to air pollution in the Swedish population above 60 years of age, we used the latest concentration response functions (CRF) between PM2.5 exposure and dementia incidence, based on ten longitudinal cohort studies, for the population above 60 years of age. To estimate the monetary burden of attributable cases, we calculated total costs related to dementia, including direct and indirect lifetime costs and intangible costs by including quality-adjusted life years (QALYs) lost. Two different monetary valuations of QALYs in Sweden were used to estimate the monetary value of reduced quality-of-life from two different payer perspectives.

RESULTS: The annual number of dementia cases attributable to PM2.5 exposure was estimated to be 820, which represents 5% of the annual dementia cases in Sweden. Direct and indirect lifetime average cost per dementia case was estimated to correspond € 213,000. A reduction of PM2.5 by 1 μg/m3 was estimated to yield 101 fewer cases of dementia incidences annually, resulting in an estimated monetary benefit ranging up to 0.01% of the Swedish GDP in 2019.

CONCLUSION: This study estimated that 5% of annual dementia cases could be attributed to PM2.5 exposure, and that the resulting monetary burden is substantial. These findings suggest the need to consider airborne toxic pollutants associated with dementia incidence in public health policy decisions.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2021
Keywords
Air pollution, Dementia, Incidence, PM2.5, Particulate matter, QALY, Societal costs
National Category
Occupational Health and Environmental Health
Identifiers
urn:nbn:se:umu:diva-183725 (URN)10.1186/s12940-021-00750-x (DOI)000655720900001 ()34044832 (PubMedID)2-s2.0-85106988294 (Scopus ID)
Funder
Swedish Research Council Formas, 2017-00898
Available from: 2021-05-31 Created: 2021-05-31 Last updated: 2023-09-05Bibliographically approved
Oudin Åström, D., Adolfsson, R., Segersson, D., Forsberg, B. & Oudin, A. (2021). Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia: Results from the Betula Cohort in Northern Sweden. Journal of Alzheimer's Disease, 81(1), 83-85
Open this publication in new window or tab >>Local Contrasts in Concentration of Ambient Particulate Air Pollution (PM2.5) and Incidence of Alzheimer's Disease and Dementia: Results from the Betula Cohort in Northern Sweden
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2021 (English)In: Journal of Alzheimer's Disease, ISSN 1387-2877, E-ISSN 1875-8908, Vol. 81, no 1, p. 83-85Article in journal (Refereed) Published
Abstract [en]

Exposure to fine particulate air pollution (PM2.5) is emerging as a risk factor for Alzheimer's disease (AD), but existing studies are still limited and heterogeneous. We have previously studied the association between dementia (AD and vascular dementia) and PM2.5 stemming from vehicle exhaust and wood-smoke in the Betula cohort in Northern Sweden. The aim of this commentary is to estimate the association between total PM2.5 and dementia in the Betula cohort, which is more relevant to include in future meta-estimates than the source-specific estimates. The hazard ratio for incident dementia associated with a 1μg/m3 increase in local PM2.5 was 1.38 (95% confidence interval: 0.99 -1.92). The interpretation of our results is that they indicate an association between local contrasts in concentration of PM2.5 at the residential address and incidence of dementia in a low-level setting.

Place, publisher, year, edition, pages
IOS Press, 2021
Keywords
Air pollution, Alzheimer’s disease, PM2.5, dementia, particulate air pollution
National Category
Occupational Health and Environmental Health
Identifiers
urn:nbn:se:umu:diva-181761 (URN)10.3233/JAD-201538 (DOI)000648474400006 ()33749652 (PubMedID)2-s2.0-85105728122 (Scopus ID)
Funder
Swedish Research Council Formas, 2017- 108 00898
Available from: 2021-03-25 Created: 2021-03-25 Last updated: 2021-06-16Bibliographically approved
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