umu.sePublikasjoner
Endre søk
Link to record
Permanent link

Direct link
BETA
Forsner, Maria
Publikasjoner (10 av 24) Visa alla publikasjoner
Arouca, A. B., Santaliestra-Pasías, A. M., Moreno, L. A., Marcos, A., Widhalm, K., Molnár, D., . . . Michels, N. (2019). Diet as a moderator in the association of sedentary behaviors with inflammatory biomarkers among adolescents in the HELENA study. European Journal of Nutrition, 58(5), 2051-2065
Åpne denne publikasjonen i ny fane eller vindu >>Diet as a moderator in the association of sedentary behaviors with inflammatory biomarkers among adolescents in the HELENA study
Vise andre…
2019 (engelsk)Inngår i: European Journal of Nutrition, ISSN 1436-6207, E-ISSN 1436-6215, Vol. 58, nr 5, s. 2051-2065Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

AIM: To assess if a healthy diet might attenuate the positive sedentary-inflammation relation, whereas an unhealthy diet may increase the effect of sedentary behaviors on inflammatory biomarkers.

METHODS: In 618 adolescents (13-17 years) of the European HELENA study, data were available on body composition, a set of inflammation markers, and food intake assessed by a self-administered computerized 24 h dietary recall for 2 days. A 9-point Mediterranean diet score and an antioxidant-rich diet z-score were used as dietary indices and tested as moderators. A set of low-grade inflammatory characteristics was used as outcome: several cytokines in an inflammatory ratio (IL-6, IL-10, TNF-α, TGFβ-1), C-reactive protein, three cell-adhesion molecules (sVCAM-1, sICAM-1, sE-selectin), three cardiovascular risk markers (GGT, ALT, homocysteine) and three immune cell types (white blood cells, lymphocytes, CD3). Sedentary behaviors were self-reported and analyzed as total screen time. Multiple linear regression analyses tested moderation by diet in the sedentary behaviors-inflammation association adjusted for age, sex, country, adiposity (sum of six skinfolds), parental education, and socio-economic status.

RESULTS: Both diet scores, Mediterranean and antioxidant-rich diet, were significant protective moderators in the effect of sedentary behaviors on alanine-transaminase enzyme (P = 0.014; P = 0.027), and on the pro/anti-inflammatory cytokine ratio (P = 0.001; P = 0.004), but not on other inflammatory parameters.

CONCLUSION: A higher adherence to the Mediterranean diet or an antioxidant-rich diet may attenuate the onset of oxidative stress signs associated by sedentary behaviors, whereas a poor diet seems to increase inflammation.

sted, utgiver, år, opplag, sider
Springer, 2019
Emneord
Adolescents, HELENA study, Low-grade inflammation, Mediterranean diet, Moderation, Sedentary behavior
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-151272 (URN)10.1007/s00394-018-1764-4 (DOI)000476492800027 ()29974229 (PubMedID)
Tilgjengelig fra: 2018-08-31 Laget: 2018-08-31 Sist oppdatert: 2019-09-06bibliografisk kontrollert
Wisnuwardani, R. W., De Henauw, S., Androutsos, O., Forsner, M., Gottrand, F., Huybrechts, I., . . . Michels, N. (2019). Estimated dietary intake of polyphenols in European adolescents: the HELENA study. European Journal of Nutrition, 58(6), 2345-2363
Åpne denne publikasjonen i ny fane eller vindu >>Estimated dietary intake of polyphenols in European adolescents: the HELENA study
Vise andre…
2019 (engelsk)Inngår i: European Journal of Nutrition, ISSN 1436-6207, E-ISSN 1436-6215, Vol. 58, nr 6, s. 2345-2363Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

PURPOSE: Knowledge about polyphenols intakes and their determinants among adolescents might be helpful for planning targeted prevention strategies at an early age.

METHODS: In the European multicenter cross-sectional HELENA study of 2006-2007, 2428 subjects (47% boys) had data on dietary intake of polyphenols from 2 non-consecutive 24 h recalls via linking with the Phenol-Explorer database. Differences by sex, age, country, BMI, maternal education, paternal education, family affluence, smoking status, alcohol use, and physical activity were explored by linear regression.

RESULTS: Median, lower and upper quartiles of polyphenol intakes were 326, 167 and 564 mg/day, respectively. Polyphenol intake was significantly higher in the oldest (16-17.49 years), girls, non-Mediterranean countries, lowest BMI, highest paternal education, and alcohol consumers. Main food contributors were fruit (23%, mainly apple and pear, i.e., 16.3%); chocolate products (19.2%); and fruit and vegetable juices (15.6%). Main polyphenol classes were flavonoids (75-76% of total) and phenolic acids (17-19% of total). The three most consumed polyphenols were proanthocyanidin polymers (> 10 mers), hesperidin, and proanthocyanidin 4-6 oligomers.

CONCLUSION: The current study provided for the first time numbers on the total polyphenol intake and their main food sources in a heterogeneous group of European adolescents. Major differences with adult populations are the lower polyphenol consumption and the major food sources, such as chocolate and biscuits. The discussed determinants and polyphenol types already point to some important population groups that need to be targeted in future public health initiatives.

sted, utgiver, år, opplag, sider
Springer, 2019
Emneord
Polyphenol, Consumption, Food contributors, HELENA, Determinants, Mediterranean
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-151271 (URN)10.1007/s00394-018-1787-x (DOI)000480593400009 ()30062491 (PubMedID)
Merknad

First Online: 30 July 2018

Tilgjengelig fra: 2018-08-31 Laget: 2018-08-31 Sist oppdatert: 2019-09-02bibliografisk kontrollert
Arouca, A. B., Meirhaeghe, A., Dallongeville, J., Moreno, L. A., Lourenço, G. J., Marcos, A., . . . Michels, N. (2019). Interplay between the Mediterranean diet and C-reactive protein genetic polymorphisms towards inflammation in adolescents.. Clinical Nutrition, Article ID S0261-5614(19)33028-6.
Åpne denne publikasjonen i ny fane eller vindu >>Interplay between the Mediterranean diet and C-reactive protein genetic polymorphisms towards inflammation in adolescents.
Vise andre…
2019 (engelsk)Inngår i: Clinical Nutrition, ISSN 0261-5614, E-ISSN 1532-1983, artikkel-id S0261-5614(19)33028-6Artikkel i tidsskrift (Fagfellevurdert) In press
Abstract [en]

AIM: From a nutrigenetics perspective, we aim to investigate the moderating role of the Mediterranean diet and each of its subgroups in the association between C-reactive protein (CRP) gene polymorphisms and CRP blood concentration in adolescents.

METHODS: In 562 adolescents (13-17 y) of the European HELENA study, data was available on circulating CRP levels as inflammatory biomarker, three CRP gene SNPs (rs3093068, rs1204, rs1130864), food intake determined by a self-administered computerized 24 h-dietary recall for 2 days, and body composition. A 9-point Mediterranean diet score and each food subgroup were tested as moderator via SNP*diet interaction. Analyzes were adjusted for age, sex, puberty, adiposity and socioeconomic status.

RESULTS: The minor allele frequencies of rs3093068 and rs1130864 SNPs (GG and TT, respectively) were associated with higher CRP concentrations, while rs1205 (CT/TT) was associated with lower CRP concentrations. There were significant interactions between rs3093068 and Mediterranean diet (B = -0.1139, p = 0.011), or the fish food subgroup (B = -0.0090, p = 0.022), so that those with the highest genetic CRP risk underwent the highest CRP attenuation by a healthier diet. Although the effect of diet and SNP was substantial, the explained variance by interaction was only 1%.

CONCLUSION: Greater adherence to the Mediterranean diet and particularly its fish component was associated with a lower CRP blood concentrations especially in those at highest genetic risk due to the rs3093068 SNP.

Emneord
C-reactive protein, Inflammation, Interaction, Mediterranean diet, Nutrigenomics, Single nucleotide polymorphism
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-164179 (URN)10.1016/j.clnu.2019.08.016 (DOI)31500937 (PubMedID)2-s2.0-85071870278 (Scopus ID)
Tilgjengelig fra: 2019-10-15 Laget: 2019-10-15 Sist oppdatert: 2019-10-18
diva2:1342361
Åpne denne publikasjonen i ny fane eller vindu >>National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries
Vise andre…
2019 (engelsk)Inngår i: International Journal of Epidemiology, ISSN 0300-5771, E-ISSN 1464-3685Artikkel i tidsskrift (Fagfellevurdert) Epub ahead of print
Abstract [en]

Background: Although high-density lipoprotein (HDL) and non-HDL cholesterol have opposite associations with coronary heart disease, multi-country reports of lipid trends only use total cholesterol (TC). Our aim was to compare trends in total, HDL and non-HDL cholesterol and the total-to-HDL cholesterol ratio in Asian and Western countries.

Methods: We pooled 458 population-based studies with 82.1 million participants in 23 Asian and Western countries. We estimated changes in mean total, HDL and non-HDL cholesterol and mean total-to-HDL cholesterol ratio by country, sex and age group.

Results: Since ∼1980, mean TC increased in Asian countries. In Japan and South Korea, the TC rise was due to rising HDL cholesterol, which increased by up to 0.17 mmol/L per decade in Japanese women; in China, it was due to rising non-HDL cholesterol. TC declined in Western countries, except in Polish men. The decline was largest in Finland and Norway, at ∼0.4 mmol/L per decade. The decline in TC in most Western countries was the net effect of an increase in HDL cholesterol and a decline in non-HDL cholesterol, with the HDL cholesterol increase largest in New Zealand and Switzerland. Mean total-to-HDL cholesterol ratio declined in Japan, South Korea and most Western countries, by as much as ∼0.7 per decade in Swiss men (equivalent to ∼26% decline in coronary heart disease risk per decade). The ratio increased in China.

Conclusions: HDL cholesterol has risen and the total-to-HDL cholesterol ratio has declined in many Western countries, Japan and South Korea, with only a weak correlation with changes in TC or non-HDL cholesterol.

sted, utgiver, år, opplag, sider
Oxford University Press, 2019
Emneord
HDL cholesterol, LDL cholesterol, Total cholesterol, blood lipids, multi-country study
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-162084 (URN)10.1093/ije/dyz099 (DOI)31321439 (PubMedID)
Prosjekter
NCD Risk Factor Collaboration (NCD-RisC)
Tilgjengelig fra: 2019-08-13 Laget: 2019-08-13 Sist oppdatert: 2019-09-06
Wisnuwardani, R. W., De Henauw, S., Forsner, M., Gottrand, F., Huybrechts, I., Knaze, V., . . . Michels, N. (2019). Polyphenol intake and metabolic syndrome risk in European adolescents: the HELENA study. European Journal of Nutrition
Åpne denne publikasjonen i ny fane eller vindu >>Polyphenol intake and metabolic syndrome risk in European adolescents: the HELENA study
Vise andre…
2019 (engelsk)Inngår i: European Journal of Nutrition, ISSN 1436-6207, E-ISSN 1436-6215Artikkel i tidsskrift (Fagfellevurdert) Epub ahead of print
Abstract [en]

Purpose: The role of polyphenol intake during adolescence to prevent metabolic syndrome (MetS) is little explored. This study aimed to evaluate the association between intake of total polyphenols, polyphenol classes and the 10 most consumed individual polyphenols with MetS risk in European adolescents.

Methods: Of the cross-sectional HELENA study, 657 adolescents (54% girls; 14.8% overweight; 12.5–17.5 year) had a fasting blood sample and polyphenol intake data from two non-consecutive 24-h recalls matched with the Phenol-Explorer database. MetS was defined via the pediatric American Heart Association definition. Multilevel linear regressions examined the associations of polyphenol quartiles with MetS components, while logistic regression examined the associations with MetS risk.

Results: After adjusting for all potential confounders (socio-demographics and nine nutrients), total polyphenol intake, polyphenol classes and individual polyphenols were not associated with MetS risk. From all MetS components, only BMI z-score was modestly inversely associated with total polyphenol intake. Further sub analyses on polyphenol classes revealed that flavonoid intake was significantly associated with higher diastolic blood pressure and lower BMI, and phenolic acid intake was associated with higher low-density cholesterol. For individual polyphenols, the above BMI findings were often confirmed (not independent from dietary intake) and a few associations were found with insulin resistance.

Conclusion: Higher intakes of total polyphenols and flavonoids were inversely associated with BMI. No consistent associations were found for other MetS components.

sted, utgiver, år, opplag, sider
Heidelberg: Springer Berlin/Heidelberg, 2019
Emneord
Cholesterol, Flavonoid, Obesity, Polyphenol, Risk factor, Youth
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-157992 (URN)10.1007/s00394-019-01946-1 (DOI)30903362 (PubMedID)2-s2.0-85064040584 (Scopus ID)
Tilgjengelig fra: 2019-04-09 Laget: 2019-04-09 Sist oppdatert: 2019-04-26
NCD Risk Factor Collaboration (NCD-RisC), . (2019). Rising rural body-mass index is the main driver of the global obesity epidemic in adults [Letter to the editor]. Nature, 569(7755), 260-264
Åpne denne publikasjonen i ny fane eller vindu >>Rising rural body-mass index is the main driver of the global obesity epidemic in adults
2019 (engelsk)Inngår i: Nature, ISSN 0028-0836, E-ISSN 1476-4687, Vol. 569, nr 7755, s. 260-264Artikkel i tidsskrift, Letter (Fagfellevurdert) Published
Abstract [en]

Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities1,2. This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity3,4,5,6. Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017—and more than 80% in some low- and middle-income regions—was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing—and in some countries reversal—of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories.

HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-159114 (URN)10.1038/s41586-019-1171-x (DOI)000467473600049 ()31068725 (PubMedID)
Tilgjengelig fra: 2019-05-17 Laget: 2019-05-17 Sist oppdatert: 2019-06-19bibliografisk kontrollert
Esteban-Cornejo, I., Henriksson, P., Cadenas-Sanchez, C., Vanhelst, J., Forsner, M., Gottrand, F., . . . Ortega, F. B. (2018). Early life programming of attention capacity in adolescents: The HELENA study. Maternal and Child Nutrition, 14(1), Article ID e12451.
Åpne denne publikasjonen i ny fane eller vindu >>Early life programming of attention capacity in adolescents: The HELENA study
Vise andre…
2018 (engelsk)Inngår i: Maternal and Child Nutrition, ISSN 1740-8695, E-ISSN 1740-8709, Vol. 14, nr 1, artikkel-id e12451Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

The study aims to examine the individual and combined association of early life factors (birth weight, birth length, and any and exclusive breastfeeding) with attention capacity in adolescents. The study included 421 European adolescents (243 girls), aged 12.5-17.5 years, who participated in the Healthy Lifestyle in Europe by Nutrition in Adolescence Study. Body weight and length at birth of adolescents were collected from parental records. The duration of any and exclusive breastfeeding were self-reported. The d2 Test of Attention was administered to assess attention capacity. The main results showed that birth weight, birth length, breastfeeding, and exclusive breastfeeding were related to attention capacity in boys (β ranging from 0.144 to 0.196; all p < .05) after adjustment for age, centre, gestational age, maternal education, family affluence scale, and body mass index. Among boys, differences in attention capacity were found according to tertiles of birth weight and birth length (p < .05), as well as borderline significant differences across groups of any and exclusive breastfeeding (p = 0.055 and p = 0.108, respectively) after adjusting for potential confounders. In addition, boys with 3 early life risk factors (low birth weight, low birth length, and <3 months of breastfeeding) had significantly lower scores in attention capacity compared with boys with 0 risk factors (percentile score - 15.88; p = 0.009). In conclusion, early life factors, both separately and combined, may influence attention capacity in male European adolescents. Importantly, the combination of the 3 early life risk factors, low birth weight, low birth length, and <3 months of breastfeeding, even in normal ranges, may provide the highest reduction in attention capacity.

sted, utgiver, år, opplag, sider
John Wiley & Sons, 2018
Emneord
adolescent, attention capacity, birth length, birth weight, breastfeeding, early life factors
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-146743 (URN)10.1111/mcn.12451 (DOI)000418336700012 ()28401662 (PubMedID)
Tilgjengelig fra: 2018-04-18 Laget: 2018-04-18 Sist oppdatert: 2019-08-15bibliografisk kontrollert
Michels, N., Vynckier, L., Moreno, L. A., Beghin, L., de la O, A., Forsner, M., . . . De Henauw, S. (2018). Mediation of psychosocial determinants in the relation between socio-economic status and adolescents' diet quality.. European Journal of Nutrition, 57(3), 951-963
Åpne denne publikasjonen i ny fane eller vindu >>Mediation of psychosocial determinants in the relation between socio-economic status and adolescents' diet quality.
Vise andre…
2018 (engelsk)Inngår i: European Journal of Nutrition, ISSN 1436-6207, E-ISSN 1436-6215, Vol. 57, nr 3, s. 951-963Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

PURPOSE: To examine the underlying reasons for the positive relation between socio-economic status (SES) and the diet quality of adolescents.

METHODS: In 2081 adolescents (12.5-17.5 years) of the European HELENA study, a continuous variable on diet quality via 2-day 24-h recalls was available. SES was reflected by parental education, parental occupation and family affluence. Mediation by several psychosocial determinants was tested: self-efficacy, availability at school and home, social support, barriers, benefits, awareness and some self-reported influencers (parents, school, taste, health, friends, food readily available, easy preparation, hunger, price and habits). Multiple mediation analyses were adjusted for age, sex and country.

RESULTS: The availability of soft drinks and fruit at home, social support, parental influence, barriers, price influence, taste influence, health influence and food being readily available were significant mediators. The multiple mediation indirect effect accounted for 23-64% of the total effect. Both occupation and education and both maternal and paternal factors could be explained by the mediation. The unavailability of soft drinks was the strongest mediator (17-44% of the total effect).

CONCLUSION: Up to 64% of the positive relation between SES and the diet quality in adolescence could be explained by several healthy eating determinants. Focusing on these factors in low-SES populations can minimize social inequalities in diet and health by improving the diet of these specific adolescents.

sted, utgiver, år, opplag, sider
Springer, 2018
Emneord
Adolescents, Diet quality, Socio-economic class, Soft drink availability
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-146744 (URN)10.1007/s00394-017-1380-8 (DOI)000427967500009 ()28160091 (PubMedID)2-s2.0-85011635928 (Scopus ID)
Tilgjengelig fra: 2018-04-18 Laget: 2018-04-18 Sist oppdatert: 2018-08-31bibliografisk kontrollert
Nilsson, S., Hanberger, L., Olinder, A. L. & Forsner, M. (2017). The Faces Emotional Coping Scale as a self-reporting instrument for coping with needle-related procedures: An initial validation study with children treated for type 1 diabetes. Journal of Child Health Care, 21(4), 392-403
Åpne denne publikasjonen i ny fane eller vindu >>The Faces Emotional Coping Scale as a self-reporting instrument for coping with needle-related procedures: An initial validation study with children treated for type 1 diabetes
2017 (engelsk)Inngår i: Journal of Child Health Care, ISSN 1367-4935, E-ISSN 1741-2889, Vol. 21, nr 4, s. 392-403Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

The aim of this study was to determine the concurrent and content validity, sensitivity and inter-rater reliability of the Faces Emotional Coping Scale (FECS) to evaluate the children's anticipation of the level of emotional coping in conjunction with a venepuncture. A total of 153 children with type 1 diabetes and 86 of their parents participated in the study. The age of the children, 76 of whom were boys, ranged from 7 to 18 years. The child and his or her parent reported the child's coping ability, and the child reported the pain intensity and unpleasantness of a venepuncture. The child also wrote a short narrative about his or her experience of the needle procedure. The FECS correlated negatively with the Coloured Analogue Scale and the Facial Affective Scale and positively with the FECS by proxy. The narratives of 90 children correlated negatively with the FECS. Younger children reported significantly lower scores than older children did regarding their ability to cope with a venepuncture. The children's scores on the FECS showed good agreement with the parents' scores. In this study, the FECS was deemed valid for measuring children's ability to cope with their emotions when undergoing needle-related procedures like venepuncture.

sted, utgiver, år, opplag, sider
SAGE PUBLICATIONS LTD, 2017
Emneord
Child, coping, needle-related procedures, pain, pain unpleasantness
HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-142961 (URN)10.1177/1367493517729041 (DOI)000415950500004 ()29110524 (PubMedID)
Tilgjengelig fra: 2017-12-14 Laget: 2017-12-14 Sist oppdatert: 2018-06-09bibliografisk kontrollert
Zhou, B., Bentham, J., Di Cesare, M., Bixby, H., Danaei, G., Cowan, M. J., . . . Zuniga Cisneros, J. (2017). Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19.1 million participants. The Lancet, 389(10064), 37-55
Åpne denne publikasjonen i ny fane eller vindu >>Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19.1 million participants
Vise andre…
2017 (engelsk)Inngår i: The Lancet, ISSN 0140-6736, E-ISSN 1474-547X, Vol. 389, nr 10064, s. 37-55Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Methods: For this analysis, we pooled national, subnational, or community population-based studies that had measured blood pressure in adults aged 18 years and older. We used a Bayesian hierarchical model to estimate trends from 1975 to 2015 in mean systolic and mean diastolic blood pressure, and the prevalence of raised blood pressure for 200 countries. We calculated the contributions of changes in prevalence versus population growth and ageing to the increase in the number of adults with raised blood pressure.

Findings: We pooled 1479 studies that had measured the blood pressures of 19·1 million adults. Global age-standardised mean systolic blood pressure in 2015 was 127·0 mm Hg (95% credible interval 125·7–128·3) in men and 122·3 mm Hg (121·0–123·6) in women; age-standardised mean diastolic blood pressure was 78·7 mm Hg (77·9–79·5) for men and 76·7 mm Hg (75·9–77·6) for women. Global age-standardised prevalence of raised blood pressure was 24·1% (21·4–27·1) in men and 20·1% (17·8–22·5) in women in 2015. Mean systolic and mean diastolic blood pressure decreased substantially from 1975 to 2015 in high-income western and Asia Pacific countries, moving these countries from having some of the highest worldwide blood pressure in 1975 to the lowest in 2015. Mean blood pressure also decreased in women in central and eastern Europe, Latin America and the Caribbean, and, more recently, central Asia, Middle East, and north Africa, but the estimated trends in these super-regions had larger uncertainty than in high-income super-regions. By contrast, mean blood pressure might have increased in east and southeast Asia, south Asia, Oceania, and sub-Saharan Africa. In 2015, central and eastern Europe, sub-Saharan Africa, and south Asia had the highest blood pressure levels. Prevalence of raised blood pressure decreased in high-income and some middle-income countries; it remained unchanged elsewhere. The number of adults with raised blood pressure increased from 594 million in 1975 to 1·13 billion in 2015, with the increase largely in low-income and middle-income countries. The global increase in the number of adults with raised blood pressure is a net effect of increase due to population growth and ageing, and decrease due to declining age-specific prevalence.

Interpretation: During the past four decades, the highest worldwide blood pressure levels have shifted from high-income countries to low-income countries in south Asia and sub-Saharan Africa due to opposite trends, while blood pressure has been persistently high in central and eastern Europe.

HSV kategori
Identifikatorer
urn:nbn:se:umu:diva-132031 (URN)10.1016/S0140-6736(16)31919-5 (DOI)000391264000037 ()
Tilgjengelig fra: 2017-03-29 Laget: 2017-03-29 Sist oppdatert: 2019-05-23bibliografisk kontrollert
Organisasjoner