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2024 (English)In: Diabetes Care, ISSN 0149-5992, E-ISSN 1935-5548, Vol. 47, no 11, p. 2012-2016Article in journal (Refereed) Published
Abstract [en]
OBJECTIVE: To compare the prevalence of parental diabetes between children with and without type 1 diabetes (T1D), and to compare clinical characteristics at diagnosis of T1D in children with, versus without, a family history of diabetes.
RESEARCH DESIGN AND METHODS: Parental diabetes among children with T1D was compared with a general population cohort. Clinical characteristics were compared by family history of diabetes in parents and grandparents of 3,603 children with T1D using relative risk (RR) and ANOVA.
RESULTS: Children with T1D more often had parents with type 2 diabetes (T2D) (RR 1.88; P < 0.001) than did children without diabetes. Children with T1D and a family history of T2D were more likely to be overweight or obese (P = 0.002).
CONCLUSIONS: A family history of T2D and being overweight may contribute to increased risk of T1D.
Place, publisher, year, edition, pages
American Diabetes Association, 2024
National Category
Endocrinology and Diabetes
Identifiers
urn:nbn:se:umu:diva-230187 (URN)10.2337/dc24-0534 (DOI)001345278000004 ()39302847 (PubMedID)2-s2.0-85207597199 (Scopus ID)
Funder
Samariten foundation for paediatric researchSwedish Child Diabetes Foundation
2024-09-302024-09-302024-11-22Bibliographically approved