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Andersson, Magnus, ProfessorORCID iD iconorcid.org/0000-0002-9835-3263
Publications (10 of 111) Show all publications
Sil, T. B., Malyshev, D., Aspholm, M. & Andersson, M. (2025). Boosting hypochlorite’s disinfection power through pH modulation. BMC Microbiology, 25(1), Article ID 101.
Open this publication in new window or tab >>Boosting hypochlorite’s disinfection power through pH modulation
2025 (English)In: BMC Microbiology, E-ISSN 1471-2180, Vol. 25, no 1, article id 101Article in journal (Refereed) Published
Abstract [en]

Purpose: Hypochlorite-based formulations are widely used for surface disinfection. However, the efficacy of hypochlorite against spore-forming bacteria varies significantly in the literature. Although neutral or low pH hypochlorite solutions are effective sporicides due to the formation of hypochlorous acid (HOCl), their optimal conditions and the specific role of pH in disinfection remain unclear. These conditions also increase the solution’s corrosiveness and compromise its shelf life. Therefore, further research is needed to identify the pH conditions that balance solution stability and effective hypochlorite-based spore disinfection.

Results: This study investigates the impact of neutral to alkaline pH on the sporicidal efficiency of hypochlorite against a pathogenic Bacillus cereus strain. We apply a 5,000 ppm hypochlorite formulation for 10-min across a pH range of 7.0-12.0, simulating common surface decontamination practices. Our results demonstrate that hypochlorite is largely ineffective at pH levels above 11.0, showing less than 1-log reduction in spore viability. However, there is a significant increase in sporicidal efficiency between pH 11.0 and 9.5, with a 4-log reduction in viability. This pH level corresponds to 2 - 55 ppm of the HOCl ionic form of hypochlorite. Further reduction in pH slightly improves the disinfection efficacy. However, the shelf life of hypochlorite solution decreases exponentially below pH 8.5. To explore the pH-dependent efficacy of hypochlorite, Raman spectroscopy and fluorescence imaging were used to investigate the biochemical mechanisms of spore decontamination. Results showed that lower pH enhances spore permeability and promotes calcium dipicolinic acid (CaDPA) release from the core.

Conclusion: Our results highlight the complex relationship between pH, sporicidal efficacy of hypochlorite, and its shelf life. While lower pH enhances the sporicidal efficiency, it compromises the solution’s shelf life. A pH of 9.5 offers a balance, significantly improving shelf life compared to previously suggested pH ranges 7.0-8.0 while maintaining effective spore inactivation. Our findings challenge the common practice of diluting sodium hypochlorite with water to a 5,000 ppm solution, as this highly alkaline solution (pH of 11.9), is insufficient for eliminating B. cereus spores, even after a 10-min exposure. These findings are critical for improving disinfection practices, highlighting the importance of optimizing sodium hypochlorite effectiveness through pH adjustments before application.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2025
Keywords
Bacillus, Decontamination, HOCl, NaOCl, Raman, Spores
National Category
Water Engineering
Identifiers
urn:nbn:se:umu:diva-236477 (URN)10.1186/s12866-025-03831-w (DOI)001434989900006 ()40021972 (PubMedID)2-s2.0-85219605294 (Scopus ID)
Available from: 2025-03-19 Created: 2025-03-19 Last updated: 2025-03-19Bibliographically approved
Segervald, J., Malyshev, D., Öberg, R., Zäll, E., Jia, X., Wågberg, T. & Andersson, M. (2025). Ultra-sensitive detection of bacterial spores via SERS. ACS Sensors, 10(2), 1237-1248
Open this publication in new window or tab >>Ultra-sensitive detection of bacterial spores via SERS
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2025 (English)In: ACS Sensors, E-ISSN 2379-3694, Vol. 10, no 2, p. 1237-1248Article in journal (Refereed) Published
Abstract [en]

Bacterial spores are highly resilient and capable of surviving extreme conditions, making them a persistent threat in contexts such as disease transmission, food safety, and bioterrorism. Their ability to withstand conventional sterilization methods necessitates rapid and accurate detection techniques to effectively mitigate the risks they present. In this study, we introduce a surface-enhanced Raman spectroscopy (SERS) approach for detecting Bacillus thuringiensis spores by targeting calcium dipicolinate acid (CaDPA), a biomarker uniquely associated with bacterial spores. Our method uses probe sonication to disrupt spores, releasing their CaDPA, which is then detected by SERS on drop-dried supernatant mixed with gold nanorods. This simple approach enables the selective detection of CaDPA, distinguishing it from other spore components and background noise. We demonstrate detection of biogenic CaDPA from concentrations as low as 103 spores/mL, with sensitivity reaching beyond CaDPA levels of a single spore. Finally, we show the method’s robustness by detecting CaDPA from a realistic sample of fresh milk mixed with spores. These findings highlight the potential of SERS as a sensitive and specific technique for bacterial spore detection, with implications for fields requiring rapid and reliable spore identification.

Place, publisher, year, edition, pages
American Chemical Society (ACS), 2025
Keywords
detection, DPA, nanorods, plasmonics, SERS, spores
National Category
Biochemistry Molecular Biology
Identifiers
urn:nbn:se:umu:diva-234870 (URN)10.1021/acssensors.4c03151 (DOI)001403530600001 ()39847439 (PubMedID)2-s2.0-86000382192 (Scopus ID)
Funder
Swedish Research Council, 2017-59504862Swedish Research Council, 2021-04629Swedish Research Council, 2023-04085
Available from: 2025-02-04 Created: 2025-02-04 Last updated: 2025-03-28Bibliographically approved
Öberg, R., Sil, T. B., Ohlin, C. A., Andersson, M. & Malyshev, D. (2024). Assessing CaDPA levels, metabolic activity, and spore detection through deuterium labeling. The Analyst, 149(6), 1861-1871
Open this publication in new window or tab >>Assessing CaDPA levels, metabolic activity, and spore detection through deuterium labeling
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2024 (English)In: The Analyst, ISSN 0003-2654, E-ISSN 1364-5528, Vol. 149, no 6, p. 1861-1871Article in journal (Refereed) Published
Abstract [en]

Many strains among spore-forming bacteria species are associated with food spoilage, foodborne disease, and hospital-acquired infections. Understanding the impact of environmental conditions and decontamination techniques on the metabolic activity, viability, and biomarkers of these spores is crucial for combatting them. To distinguish and track spores and to understand metabolic mechanisms, spores must be labeled. Staining or genetic modification are current methods for this, however, these methods can be time-consuming, and affect the viability and function of spore samples. In this work, we investigate the use of heavy water for permanent isotope labeling of spores and Raman spectroscopy for tracking sporulation/germination mechanisms. We also discuss the potential of this method in observing decontamination. We find that steady-state deuterium levels in the spore are achieved after only ∼48 h of incubation with 30% D2O-infused broth and sporulation, generating Raman peaks at cell silent region of 2200 and 2300 cm−1. These deuterium levels then decrease rapidly upon spore germination in non-deuterated media. We further find that unlike live spores, spores inactivated using various methods do not lose these Raman peaks upon incubation in growth media, suggesting these peaks may be used to indicate the viability of a spore sample. We further observe several Raman peaks exclusive to deuterated DPA, a spore-specific chemical biomarker, at e.g. 988 and 2300 cm−1, which can be used to track underlying changes in spores involving DPA. In conclusion, permanent spore labeling using deuterium offers a robust and non-invasive way of labeling bacterial spores for marking, viability determination, and characterising spore activity.

Place, publisher, year, edition, pages
Royal Society of Chemistry, 2024
National Category
Other Physics Topics Analytical Chemistry Other Biological Topics
Identifiers
urn:nbn:se:umu:diva-221377 (URN)10.1039/d3an02162a (DOI)001160646800001 ()38348676 (PubMedID)2-s2.0-85185190708 (Scopus ID)
Funder
Swedish Research Council, 2019-04016The Kempe Foundations, JCK-1916.2Swedish Armed Forces, 470-A400823
Available from: 2024-02-21 Created: 2024-02-21 Last updated: 2024-03-21Bibliographically approved
Öberg, R., Landström, L., Gracia-Espino, E., Larsson, A., Andersson, M. & Andersson, P. O. (2024). Characterization of carfentanil and thiofentanil using surface-enhanced raman spectroscopy and density functional theory. Journal of Raman Spectroscopy, 55(4), 481-492
Open this publication in new window or tab >>Characterization of carfentanil and thiofentanil using surface-enhanced raman spectroscopy and density functional theory
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2024 (English)In: Journal of Raman Spectroscopy, ISSN 0377-0486, E-ISSN 1097-4555, Vol. 55, no 4, p. 481-492Article in journal (Refereed) Published
Abstract [en]

Fentanyls are synthetic opioids up to 10,000 times more potent than morphine. Although initially developed for medical applications, fentanyl and its analogues have recently grown synonymous with the ongoing opioid epidemic. To combat the continued spread of these substances, there is a need for rapid and sensitive techniques for chemical detection. Surface-enhanced Raman spectroscopy (SERS) has the potential for trace detection of harmful chemical substances. However, vibrational spectra obtained by SERS often differ between SERS substrates, as well as compared with spectra from normal Raman (NR) spectroscopy. Herein, SERS and NR responses from two fentanyl analogues, carfentanil (CF) and thiofentanil (TF), were measured and analysed with support from density functional theory (DFT) modelling. Using commercially available silver nanopillar SERS substrates, the SERS signatures of samples diluted in acetonitrile between 0.01 and 1000 µg/mL were studied. Relative SERS peak intensities measured in the range of 220–1800 cm−1 vary with concentration, while SERS and NR spectra largely agree for CF at higher concentrations ((Formula presented.) 100 µg/mL). For TF, three distinct NR peaks at 262, 366 and 667 cm−1 are absent or strongly suppressed in the SERS spectrum, attributed to the lone-pair electrons of the thiophene's sulphur atom binding to the Ag surface. The concentration dependence of the Raman peak at (Formula presented.) 1000 cm−1, assigned to trigonal bending of the phenyl ring, approximately follows a Langmuir adsorption isotherm. This work elucidates similarities and differences between SERS and NR in fentanyl detection and discusses the chemical rationale behind these differences.

Place, publisher, year, edition, pages
John Wiley & Sons, 2024
Keywords
carfentanil, opioids, Raman, SERS, thiofentanil
National Category
Analytical Chemistry
Identifiers
urn:nbn:se:umu:diva-219515 (URN)10.1002/jrs.6643 (DOI)001139395600001 ()2-s2.0-85181933303 (Scopus ID)
Funder
Swedish Research Council, 2019-04016Swedish Research Council, 2018-03937The Kempe Foundations, JCK-2132
Available from: 2024-01-22 Created: 2024-01-22 Last updated: 2024-06-19Bibliographically approved
Malyshev, D., Lee, C. C. & Andersson, M. (2024). Evaluating bacterial spore preparation methods for scanning electron microscopy. Microscopy and Microanalysis, 30(3), 564-573
Open this publication in new window or tab >>Evaluating bacterial spore preparation methods for scanning electron microscopy
2024 (English)In: Microscopy and Microanalysis, ISSN 1431-9276, E-ISSN 1435-8115, Vol. 30, no 3, p. 564-573Article in journal (Refereed) Published
Abstract [en]

Scanning electron microscopy (SEM) can reveal the ultrastructure of bacterial spores, including morphology, surface features, texture, spore damage, germination, and appendages. Understanding these features can provide a basis for adherence, how physical and environmental stressors affect spore viability, integrity, and functionality, as well as the distribution and function of surface appendages. However, the spore sample preparation method can significantly impact the SEM images' appearance, resolution, and overall quality. In this study, we compare different spore preparation methods to identify optimal approaches for preparation time, spore appearance and resolved features, including the exosporium and spore pili, for SEM imaging. We use Bacillus paranthracis as model species and evaluate the efficacy of preparation protocols using different fixation and drying methods, as well as imaging under room- and cryogenic temperatures. We compare and assess method complexity to the visibility of the spore exosporium and spore appendages across different methods. Additionally, we use Haralick texture features to quantify the differences in spore surface appearance and determine the most suitable method for preserving spore structures and surface features during SEM evaluation. The findings from this study will help establish protocols for preparing bacterial spores for SEM and facilitating accurate and reliable analysis of spores' characteristics.

Place, publisher, year, edition, pages
Oxford University Press, 2024
Keywords
bacillus, fixative, Haralick, SEM, texture
National Category
Microbiology Other Physics Topics
Identifiers
urn:nbn:se:umu:diva-227941 (URN)10.1093/mam/ozae037 (DOI)001217162300001 ()2-s2.0-85198180107 (Scopus ID)
Funder
Swedish Research Council, 2019-04016
Available from: 2024-07-19 Created: 2024-07-19 Last updated: 2024-07-19Bibliographically approved
Qamar, S., Baba, A. I., Verger, S. & Andersson, M. (2024). Segmentation and characterization of macerated fibers and vessels using deep learning. Plant Methods, 20(1), Article ID 126.
Open this publication in new window or tab >>Segmentation and characterization of macerated fibers and vessels using deep learning
2024 (English)In: Plant Methods, E-ISSN 1746-4811, Vol. 20, no 1, article id 126Article in journal (Refereed) Published
Abstract [en]

Purpose: Wood comprises different cell types, such as fibers, tracheids and vessels, defining its properties. Studying cells’ shape, size, and arrangement in microscopy images is crucial for understanding wood characteristics. Typically, this involves macerating (soaking) samples in a solution to separate cells, then spreading them on slides for imaging with a microscope that covers a wide area, capturing thousands of cells. However, these cells often cluster and overlap in images, making the segmentation difficult and time-consuming using standard image-processing methods.

Results: In this work, we developed an automatic deep learning segmentation approach that utilizes the one-stage YOLOv8 model for fast and accurate segmentation and characterization of macerated fiber and vessel form aspen trees in microscopy images. The model can analyze 32,640 x 25,920 pixels images and demonstrate effective cell detection and segmentation, achieving a mAP0.5-0.95 of 78 %. To assess the model’s robustness, we examined fibers from a genetically modified tree line known for longer fibers. The outcomes were comparable to previous manual measurements. Additionally, we created a user-friendly web application for image analysis and provided the code for use on Google Colab.

Conclusion: By leveraging YOLOv8’s advances, this work provides a deep learning solution to enable efficient quantification and analysis of wood cells suitable for practical applications.

Place, publisher, year, edition, pages
Springer Nature, 2024
Keywords
Fibers, Instance segmentation, Optical microscopy, Wood, YOLO
National Category
Computer graphics and computer vision
Identifiers
urn:nbn:se:umu:diva-228815 (URN)10.1186/s13007-024-01244-w (DOI)001290692600002 ()2-s2.0-85201277422 (Scopus ID)
Projects
Bio4Energy
Funder
The Kempe Foundations, JCK–2129.3Knut and Alice Wallenberg Foundation, 2016.0341Knut and Alice Wallenberg Foundation, 2016.0352Vinnova, 2016–00504Novo Nordisk Foundation, NNF21OC0067282
Available from: 2024-08-27 Created: 2024-08-27 Last updated: 2025-02-07Bibliographically approved
Jonsmoen, U. L., Malyshev, D., Sleutel, M., Kristensen, E. E., Zegeye, E. D., Remaut, H., . . . Aspholm, M. E. (2024). The role of endospore appendages in spore–spore interactions in the pathogenic Bacillus cereus group. Environmental Microbiology, 26(9), Article ID e16678.
Open this publication in new window or tab >>The role of endospore appendages in spore–spore interactions in the pathogenic Bacillus cereus group
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2024 (English)In: Environmental Microbiology, ISSN 1462-2912, E-ISSN 1462-2920, Vol. 26, no 9, article id e16678Article in journal (Refereed) Published
Abstract [en]

Species within the Bacillus cereus sensu lato group, known for their spore-forming ability, are recognized for their significant role in food spoilage and food poisoning. The spores of B. cereus are adorned with numerous pilus-like appendages, referred to as S-ENAs and L-ENAs. These appendages are thought to play vital roles in self-aggregation, adhesion, and biofilm formation. Our study investigates the role of S-ENAs and L-ENAs, as well as the impact of various environmental factors on spore-to-spore contacts and the interaction between spores and vegetative cells, using both bulk and single-cell approaches. Our findings indicate that ENAs, especially their tip fibrillae, play a crucial role in spore self-aggregation, but not in the adhesion of spores to vegetative cells. The absence of L-BclA, which forms the L-ENA tip fibrillum, reduced spore aggregation mediated by both S-ENAs and L-ENAs, highlighting the interconnected roles of S-ENAs and L-ENAs. We also found that increased salt concentrations in the liquid environment significantly reduced spore aggregation, suggesting a charge dependency of spore-spore interactions. By shedding light on these complex interactions, our study offers valuable insights into spore dynamics. This knowledge can inform future studies on spore behaviour in environmental settings and assist in developing strategies to manage bacterial aggregation for beneficial purposes, such as controlling biofilms in food production equipment.

Place, publisher, year, edition, pages
John Wiley & Sons, 2024
National Category
Biochemistry Molecular Biology Microbiology
Identifiers
urn:nbn:se:umu:diva-229641 (URN)10.1111/1462-2920.16678 (DOI)001304426600001 ()39228067 (PubMedID)2-s2.0-85203194273 (Scopus ID)
Funder
Swedish Research Council, 2019-04016The Research Council of Norway, 335029
Available from: 2024-09-16 Created: 2024-09-16 Last updated: 2025-02-20Bibliographically approved
Öberg, R., Sil, T. B., Johansson, A. C., Malyshev, D., Landström, L., Johansson, S., . . . Andersson, P. O. (2024). UV-induced spectral and morphological changes in bacterial spores for inactivation assessment. Journal of Physical Chemistry B, 128(7), 1638-1646
Open this publication in new window or tab >>UV-induced spectral and morphological changes in bacterial spores for inactivation assessment
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2024 (English)In: Journal of Physical Chemistry B, ISSN 1520-6106, E-ISSN 1520-5207, Vol. 128, no 7, p. 1638-1646Article in journal (Refereed) Published
Abstract [en]

The ability to detect and inactivate spore-forming bacteria is of significance within, for example, industrial, healthcare, and defense sectors. Not only are stringent protocols necessary for the inactivation of spores but robust procedures are also required to detect viable spores after an inactivation assay to evaluate the procedure’s success. UV radiation is a standard procedure to inactivate spores. However, there is limited understanding regarding its impact on spores’ spectral and morphological characteristics. A further insight into these UV-induced changes can significantly improve the design of spore decontamination procedures and verification assays. This work investigates the spectral and morphological changes to Bacillus thuringiensis spores after UV exposure. Using absorbance and fluorescence spectroscopy, we observe an exponential decay in the spectral intensity of amino acids and protein structures, as well as a logistic increase in dimerized DPA with increased UV exposure on bulk spore suspensions. Additionally, using micro-Raman spectroscopy, we observe DPA release and protein degradation with increased UV exposure. More specifically, the protein backbone’s 1600–1700 cm–1 amide I band decays slower than other amino acid-based structures. Last, using electron microscopy and light scattering measurements, we observe shriveling of the spore bodies with increased UV radiation, alongside the leaking of core content and disruption of proteinaceous coat and exosporium layers. Overall, this work utilized spectroscopy and electron microscopy techniques to gain new understanding of UV-induced spore inactivation relating to spore degradation and CaDPA release. The study also identified spectroscopic indicators that can be used to determine spore viability after inactivation. These findings have practical applications in the development of new spore decontamination and inactivation validation methods.

Place, publisher, year, edition, pages
American Chemical Society (ACS), 2024
National Category
Microbiology Analytical Chemistry Other Physics Topics
Identifiers
urn:nbn:se:umu:diva-221378 (URN)10.1021/acs.jpcb.3c07062 (DOI)001167255400001 ()38326108 (PubMedID)2-s2.0-85185157140 (Scopus ID)
Funder
Swedish Research Council, 2019-04016The Kempe Foundations, JCK-1916.2Swedish Armed Forces, 470-A400823
Note

Published as part of The Journal of Physical Chemistry B virtual special issue “Advances in Cellular Biophysics”.

Available from: 2024-02-21 Created: 2024-02-21 Last updated: 2025-04-24Bibliographically approved
Qamar, S., Öberg, R., Malyshev, D. & Andersson, M. (2023). A hybrid CNN-Random Forest algorithm for bacterial spore segmentation and classification in TEM images. Scientific Reports, 13(1), Article ID 18758.
Open this publication in new window or tab >>A hybrid CNN-Random Forest algorithm for bacterial spore segmentation and classification in TEM images
2023 (English)In: Scientific Reports, E-ISSN 2045-2322, Vol. 13, no 1, article id 18758Article in journal (Refereed) Published
Abstract [en]

We present a new approach to segment and classify bacterial spore layers from Transmission Electron Microscopy (TEM) images using a hybrid Convolutional Neural Network (CNN) and Random Forest (RF) classifier algorithm. This approach utilizes deep learning, with the CNN extracting features from images, and the RF classifier using those features for classification. The proposed model achieved 73% accuracy, 64% precision, 46% sensitivity, and 47% F1-score with test data. Compared to other classifiers such as AdaBoost, XGBoost, and SVM, our proposed model demonstrates greater robustness and higher generalization ability for non-linear segmentation. Our model is also able to identify spores with a damaged core as verified using TEMs of chemically exposed spores. Therefore, the proposed method will be valuable for identifying and characterizing spore features in TEM images, reducing labor-intensive work as well as human bias.

Place, publisher, year, edition, pages
Springer Nature, 2023
National Category
Other Physics Topics Other Computer and Information Science
Identifiers
urn:nbn:se:umu:diva-216165 (URN)10.1038/s41598-023-44212-5 (DOI)001123935800008 ()37907463 (PubMedID)2-s2.0-85175591485 (Scopus ID)
Funder
Swedish Research Council, 2019-04016The Kempe Foundations, JCK-2129.3
Available from: 2023-11-04 Created: 2023-11-04 Last updated: 2025-04-24Bibliographically approved
Valijam, S., Nilsson, D., Öberg, R., Albertsdóttir Jonsmoen, U. L., Porch, A., Andersson, M. & Malyshev, D. (2023). A lab-on-a-chip utilizing microwaves for bacterial spore disruption and detection. Biosensors & bioelectronics, 231, Article ID 115284.
Open this publication in new window or tab >>A lab-on-a-chip utilizing microwaves for bacterial spore disruption and detection
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2023 (English)In: Biosensors & bioelectronics, ISSN 0956-5663, E-ISSN 1873-4235, Vol. 231, article id 115284Article in journal (Refereed) Published
Abstract [en]

Bacterial spores are problematic in agriculture, the food industry, and healthcare, with the fallout costs from spore-related contamination being very high. Spores are difficult to detect since they are resistant to many of the bacterial disruption techniques used to bring out the biomarkers necessary for detection. Because of this, effective and practical spore disruption methods are desirable. In this study, we demonstrate the efficiency of a compact microfluidic lab-on-chip built around a coplanar waveguide (CPW) operating at 2.45 GHz. We show that the CPW generates an electric field hotspot of ∼10 kV/m, comparable to that of a commercial microwave oven, while using only 1.2 W of input power and thus resulting in negligible sample heating. Spores passing through the microfluidic channel are disrupted by the electric field and release calcium dipicolic acid (CaDPA), a biomarker molecule present alongside DNA in the spore core. We show that it is possible to detect this disruption in a bulk spore suspension using fluorescence spectroscopy. We then use laser tweezers Raman spectroscopy (LTRS) to show the loss of CaDPA on an individual spore level and that the loss increases with irradiation power. Only 22% of the spores contain CaDPA after exposure to 1.2 W input power, compared to 71% of the untreated control spores. Additionally, spores exposed to microwaves appear visibly disrupted when imaged using scanning electron microscopy (SEM). Overall, this study shows the advantages of using a CPW for disrupting spores for biomarker release and detection.

Place, publisher, year, edition, pages
Elsevier, 2023
Keywords
Raman spectroscopy, Fluorescence sep CaDPA, Waveguide, Biomarker, Bacillus
National Category
Other Physics Topics Other Electrical Engineering, Electronic Engineering, Information Engineering Biophysics
Identifiers
urn:nbn:se:umu:diva-206257 (URN)10.1016/j.bios.2023.115284 (DOI)000980707400001 ()37031508 (PubMedID)2-s2.0-85151660389 (Scopus ID)
Funder
Swedish Research Council, 2019-04016Swedish Foundation for Strategic ResearchThe Kempe Foundations, JCK-1916.2Swedish Armed Forces, 470-A400821
Available from: 2023-04-01 Created: 2023-04-01 Last updated: 2025-02-20Bibliographically approved
Projects
Anmälan om utnyttjande av återvändarbidrag för beviljade postdoktorsstipendier [2010-02495_VR]; Umeå UniversityIdentification of key adhesion mechanisms in pathogenic Gram-negative bacteria - Characterization and analysis of bacterial adhesion [2013-05379_VR]; Umeå UniversityBiophysical and Physicochemical Fingerprinting of Single Bacterial Spores [2019-04016_VR]; Umeå University; Publications
Valijam, S., Nilsson, D., Öberg, R., Albertsdóttir Jonsmoen, U. L., Porch, A., Andersson, M. & Malyshev, D. (2023). A lab-on-a-chip utilizing microwaves for bacterial spore disruption and detection. Biosensors & bioelectronics, 231, Article ID 115284. Jonsmoen, U. L., Malyshev, D., Öberg, R., Dahlberg, T., Aspholm, M. E. & Andersson, M. (2023). Endospore pili - flexible, stiff and sticky nanofibers. Biophysical Journal, 122(13), 2696-2706
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0002-9835-3263

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