umu.sePublications
Change search
Link to record
Permanent link

Direct link
BETA
Nygren, Olle
Publications (10 of 33) Show all publications
Bidleman, T. F., Brorström-Lundén, E., Hansson, K., Laudon, H., Nygren, O. & Tysklind, M. (2017). Atmospheric transport and deposition of bromoanisoles along a temperate to arctic gradient. Environmental Science and Technology, 51(19), 10974-10982
Open this publication in new window or tab >>Atmospheric transport and deposition of bromoanisoles along a temperate to arctic gradient
Show others...
2017 (English)In: Environmental Science and Technology, ISSN 1086-931X, E-ISSN 1520-6912, Vol. 51, no 19, p. 10974-10982Article in journal (Refereed) Published
Abstract [en]

Bromoanisoles (BAs) arise from O-methylation of bromophenols, produced by marine algae and invertebrates. BAs undergo sea-air exchange and are transported over the oceans. Here we report 2,4-DiBA and 2,4,6-TriBA in air and deposition on the Swedish west coast (Råö) and the interior of arctic Finland (Pallas). Results are discussed in perspective with previous measurements in the northern Baltic region in 2011−2013. BAs in air decreased from south to north in the order Råö > northern Baltic > Pallas. Geometric mean concentrations at Pallas increased significantly (p < 0.05) between 2002 and 2015 for 2,4-DiBA but not for 2,4,6-TriBA. The logarithm of BA partial pressures correlated significantly to reciprocal air temperature at the coastal station Råö and over the Baltic, but only weakly (2,4-DiBA) or not significantly (2,4,6-TriBA) at inland Pallas. Deposition fluxes of BAs were similar at both sites despite lower air concentrations at Pallas, due to greater precipitation scavenging at lower temperatures. Proportions of the two BAs in air and deposition were related to Henry’s law partitioning and source regions. Precipitation concentrations were 10−40% of those in surface water of Bothnian Bay, northern Baltic Sea. BAs deposited in the bay catchment likely enter rivers and provide an unexpected source to northern estuaries. BAs may be precursors to higher molecular weight compounds identified by others in Swedish inland lakes.

Place, publisher, year, edition, pages
Washington: American Chemical Society (ACS), 2017
Keywords
polybrominated diphenyl ethers, persistent organic pollutants, bromoperoxidase catalyzed dimerization, halogenated natural products, dibenzo-P-dioxins, OH-PBDES, methoxylated derivatives, photochemical formation, brominated anisoles, marine environment
National Category
Chemical Sciences
Identifiers
urn:nbn:se:umu:diva-140301 (URN)10.1021/acs.est.7b03218 (DOI)000412716500008 ()28885011 (PubMedID)
Projects
EcoChange
Available from: 2017-10-04 Created: 2017-10-04 Last updated: 2018-06-09Bibliographically approved
Bidleman, T. F., Laudon, H., Nygren, O., Svanberg, S. & Tysklind, M. (2017). Chlorinated pesticides and natural brominated anisoles in air at three northern Baltic stations. Environmental Pollution, 225, 381-389
Open this publication in new window or tab >>Chlorinated pesticides and natural brominated anisoles in air at three northern Baltic stations
Show others...
2017 (English)In: Environmental Pollution, ISSN 0269-7491, E-ISSN 1873-6424, Vol. 225, p. 381-389Article in journal (Refereed) Published
Abstract [en]

Abstract Polyurethane foam (PUF) disk passive samplers were deployed at one inland and two island locations in the Bothnian Bay region of the northern Baltic Sea. Uptake was linear over 81–147 d and a temperature range of −2.6 to 14.2 °C for organochlorine pesticides (OCPs) and current-use pesticides (CUPs) having log KOA ≥9 at ambient temperatures. Partial saturation of the PUF disks occurred for the more volatile OCPs hexachlorocyclohexanes (HCHs) and hexachlorobenzene (HCB), and for bromoanisoles (BAs), which are products of bromophenols released by natural and anthropogenic sources. Correction for nonlinear uptake of these was made using experimentally measured PUF-air partition coefficients. Passive-derived air concentrations of pesticides were uniform over the bay and agreed within a factor of 2 or better with levels determined by active (pumped) sampling at one of the island stations. Levels of OCPs were similar to those reported at background sites in the European and Canadian Arctic and at monitoring stations in the central Baltic and southern Scandinavia, indicating long-range transport. The insecticide chlorpyrifos was 10 times lower at bay stations than in the Canadian Arctic. Insight to sources and processes was gained by examining compound profiles. Fractions Falpha = α-HCH/(α-HCH + γ-HCH) and FTC = trans-chlordane/(trans-chlordane + cis-chlordane) at bay stations were higher than in the Norwegian and Finnish Arctic and similar to those at the southern monitoring stations. Volatilization of chlordanes from Baltic seawater may also modify FTC. Higher FTriBA = 2,4,6-TriBA/(2,4,6-TriBA + 2,4-DiBA) distinguished local volatilization from the Baltic Sea versus lower FTriBA found at the inland site and reported in air on the Norwegian coast, suggesting westerly transport from the Atlantic across Norway and Sweden.

Place, publisher, year, edition, pages
Elsevier, 2017
Keywords
Passive air sampling, Polyurethane foam, Pesticides, Halogenated Natural Products, Baltic Sea
National Category
Chemical Sciences Environmental Sciences
Identifiers
urn:nbn:se:umu:diva-134149 (URN)10.1016/j.envpol.2017.02.064 (DOI)000401679200041 ()28336095 (PubMedID)
Available from: 2017-04-27 Created: 2017-04-27 Last updated: 2018-06-09Bibliographically approved
Bidleman, T. F., Nygren, O. & Tysklind, M. (2016). Field estimates of polyurethane foam: air partition coefficients for hexachlorobenzene, alpha-hexachlorocyclohexane and bromoanisoles. Chemosphere, 159, 126-131
Open this publication in new window or tab >>Field estimates of polyurethane foam: air partition coefficients for hexachlorobenzene, alpha-hexachlorocyclohexane and bromoanisoles
2016 (English)In: Chemosphere, ISSN 0045-6535, E-ISSN 1879-1298, Vol. 159, p. 126-131Article in journal (Refereed) Published
Abstract [en]

Partition coefficients of gaseous semivolatile organic compounds (SVOCs) between polyurethane foam (PUF) and air (KPA) are needed in the estimation of sampling rates for PUF disk passive air samplers. We determined KPA in field experiments by conducting long-term (24-48 h) air sampling to saturate PUF traps and shorter runs (2-4 h) to measure air concentrations. Sampling events were done at daily mean temperatures ranging from 1.9 to 17.5 °C. Target compounds were hexachlorobenzene (HCB), alpha-hexachlorocyclohexane (α-HCH), 2,4-dibromoanisole (2,4-DiBA) and 2,4,6-tribromoanisole (2,4,6-TriBA). KPA (mL g(-1)) was calculated from quantities on the PUF traps at saturation (ng g(-1)) divided by air concentrations (ng mL(-1)). Enthalpies of PUF-to-air transfer (ΔHPA, kJ mol(-1)) were determined from the slopes of log KPA/mL g(-1) versus 1/T(K) for HCB and the bromoanisoles, KPA of α-HCH was measured only at 14.3 to 17.5 °C and ΔHPA was not determined. Experimental log KPA/mL g(-1) at 15 °C were HCB = 7.37; α-HCH = 8.08; 2,4-DiBA = 7.26 and 2,4,6-TriBA = 7.26. Experimental log KPA/mL g(-1) were compared with predictions based on an octanol-air partition coefficient (log KOA) model (Shoeib and Harner, 2002a) and a polyparameter linear free relationship (pp-LFER) model (Kamprad and Goss, 2007) using different sets of solute parameters. Predicted KP values varied by factors of 3 to over 30, depending on the compound and the model. Such discrepancies provide incentive for experimental measurements of KPA for other SVOCs.

Place, publisher, year, edition, pages
Elsevier, 2016
Keywords
Polyurethane foam, Air sampling, Semivolatile organic compounds, Bromoanisoles, Polyparameter linear free energy relationship, Octanol-air partition coefficient
National Category
Chemical Sciences Environmental Sciences
Identifiers
urn:nbn:se:umu:diva-124432 (URN)10.1016/j.chemosphere.2016.05.040 (DOI)000380417800015 ()27285381 (PubMedID)
Available from: 2016-08-11 Created: 2016-08-11 Last updated: 2018-06-07Bibliographically approved
Bidleman, T. F., Agosta, K., Andersson, A., Haglund, P., Liljelind, P., Hegmans, A., . . . Tysklind, M. (2016). Sea-air exchange of bromoanisoles and methoxylated bromodiphenylethers in the Northern Baltic. Marine Pollution Bulletin, 112(1-2), 58-64
Open this publication in new window or tab >>Sea-air exchange of bromoanisoles and methoxylated bromodiphenylethers in the Northern Baltic
Show others...
2016 (English)In: Marine Pollution Bulletin, ISSN 0025-326X, E-ISSN 1879-3363, Vol. 112, no 1-2, p. 58-64Article in journal (Refereed) Published
Abstract [en]

Halogenated natural products in biota of the Baltic Sea include bromoanisoles (BAs) and methoxylated bromodiphenyl ethers (MeO-BDEs). We identified biogenic 6-MeO-BDE47 and 2'-MeO-BDE68 in Baltic water and air for the first time using gas chromatography - high resolution mass spectrometry. Partial pressures in air were related to temperature by: log p/Pa=m/T(K)+b. We determined Henry's law constants (HLCs) of 2,4-dibromoanisole (2,4-DiBA) and 2,4,6-tribromoanisole (2,4,6-TriBA) from 5 to 30°C and revised our assessment of gas exchange in the northern Baltic. The new water/air fugacity ratios (FRs) were lower, but still indicated net volatilization in May-June for 2,4-DiBA and May - September for 2,4,6-TriBA. The net flux (negative) of BAs from Bothnian Bay (38,000km2) between May - September was revised from -1319 to -532kg. FRs of MeO-BDEs were >1, suggesting volatilization, although this is tentative due to uncertainties in their HLCs and binding to dissolved organic carbon.

Place, publisher, year, edition, pages
Elsevier, 2016
Keywords
Air-water exchange, Baltic Sea, Bromoanisoles, Halogenated natural products, Methoxylated bromodiphenyl ethers
National Category
Chemical Sciences
Identifiers
urn:nbn:se:umu:diva-126879 (URN)10.1016/j.marpolbul.2016.08.042 (DOI)000386188900017 ()27575397 (PubMedID)
Available from: 2016-10-19 Created: 2016-10-19 Last updated: 2019-04-09Bibliographically approved
Bidleman, T., Agosta, K., Andersson, A., Brorström-Lundén, E., Haglund, P., Hansson, K., . . . Wiberg, K. (2015). Atmospheric pathways of chlorinated pesticides and natural bromoanisoles in the northern Baltic Sea and its catchment. Ambio, Suppl 3(44), 472-483
Open this publication in new window or tab >>Atmospheric pathways of chlorinated pesticides and natural bromoanisoles in the northern Baltic Sea and its catchment
Show others...
2015 (English)In: Ambio, ISSN 0044-7447, E-ISSN 1654-7209, Vol. Suppl 3, no 44, p. 472-483Article in journal (Refereed) Published
Abstract [en]

Long-range atmospheric transport is a major pathway for delivering persistent organic pollutants to the oceans. Atmospheric deposition and volatilization of chlorinated pesticides and algae-produced bromoanisoles (BAs) were estimated for Bothnian Bay, northern Baltic Sea, based on air and water concentrations measured in 2011-2012. Pesticide fluxes were estimated using monthly air and water temperatures and assuming 4 months ice cover when no exchange occurs. Fluxes were predicted to increase by about 50 % under a 2069-2099 prediction scenario of higher temperatures and no ice. Total atmospheric loadings to Bothnian Bay and its catchment were derived from air-sea gas exchange and "bulk'' (precipitation ? dry particle) deposition, resulting in net gains of 53 and 46 kg year(-1) for endosulfans and hexachlorocyclohexanes, respectively, and net loss of 10 kg year(-1) for chlordanes. Volatilization of BAs releases bromine to the atmosphere and may limit their residence time in Bothnian Bay. This initial study provides baseline information for future investigations of climate change on biogeochemical cycles in the northern Baltic Sea and its catchment.

Place, publisher, year, edition, pages
Springer, 2015
Keywords
Baltic Sea, Bothnian Bay, Chlorinated pesticides, Natural brominated compounds, Atmospheric deposition, Air–sea exchange
National Category
Chemical Sciences
Identifiers
urn:nbn:se:umu:diva-106807 (URN)10.1007/s13280-015-0666-4 (DOI)000362290800014 ()26022329 (PubMedID)
Available from: 2015-08-07 Created: 2015-08-07 Last updated: 2019-04-09Bibliographically approved
Bidleman, T. F., Agosta, K., Andersson, A., Haglund, P., Nygren, O., Ripszam, M. & Tysklind, M. (2014). Air-water exchange of brominated anisoles in the northern baltic sea. Environmental Science and Technology, 48(11), 6124-6132
Open this publication in new window or tab >>Air-water exchange of brominated anisoles in the northern baltic sea
Show others...
2014 (English)In: Environmental Science and Technology, ISSN 0013-936X, E-ISSN 1520-5851, Vol. 48, no 11, p. 6124-6132Article in journal (Refereed) Published
Abstract [en]

Bromophenols produced by marine algae undergo O-methylation to form bromoanisoles (BAs), which are exchanged between water and air. BAs were determined in surface water of the northern Baltic Sea (Gulf of Bothnia, consisting of Bothnian Bay and Bothnian Sea) during 2011-2013 and on a transect of the entire Baltic in September 2013. The abundance decreased in the following order: 2,4,6-tribromoanisole (2,4,6-TBA) > 2,4-dibromoanisole (2,4-DBA) ≫ 2,6-dibromoanisole (2,6-DBA). Concentrations of 2,4-DBA and 2,4,6-TBA in September were higher in the southern than in the northern Baltic and correlated well with the higher salinity in the south. This suggests south-to-north advection and dilution with fresh riverine water enroute, and/or lower production in the north. The abundance in air over the northern Baltic also decreased in the following order: 2,4,6-TBA > 2,4-DBA. However, 2,6-DBA was estimated as a lower limit due to breakthrough from polyurethane foam traps used for sampling. Water/air fugacity ratios ranged from 3.4 to 7.6 for 2,4-DBA and from 18 to 94 for 2,4,6-TBA, indicating net volatilization. Flux estimates using the two-film model suggested that volatilization removes 980-1360 kg of total BAs from Bothnian Bay (38000 km(2)) between May and September. The release of bromine from outgassing of BAs could be up to 4-6% of bromine fluxes from previously reported volatilization of bromomethanes and bromochloromethanes.

Place, publisher, year, edition, pages
American Chemical Society (ACS), 2014
National Category
Chemical Sciences
Identifiers
urn:nbn:se:umu:diva-90338 (URN)10.1021/es5007109 (DOI)000336952000010 ()24811233 (PubMedID)
Available from: 2014-06-19 Created: 2014-06-19 Last updated: 2019-04-09Bibliographically approved
Nygren, O. & Lindahl, R. (2011). Development of a method for screening spill and leakage of antibiotics on surfaces based on wipe sampling and HPLC-MS/MS analysis. Journal of ASTM International, 8(6), 10
Open this publication in new window or tab >>Development of a method for screening spill and leakage of antibiotics on surfaces based on wipe sampling and HPLC-MS/MS analysis
2011 (English)In: Journal of ASTM International, ISSN 1546-962X, E-ISSN 1546-962X, Vol. 8, no 6, p. 10-Article in journal (Refereed) Published
Abstract [en]

A screening method for determination of spill and leakage of 12 different antibiotic substances has been developed. The method is based on wipe sampling where the sampling procedure has been simplified for screening purposes. After sample processing, the antibiotic substances are determined by liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS). Twelve antibiotic substances can be determined in the screening method: Cefadroxil, Cefalexin, Ciprofloxacin, Demeclocyklin HCl, Diaveridin, Doxycyklin, Enrofloxacin, Flukonazol, Metronidazol, Norfloxacin, Ofloxacin, and Trimetoprim. These substances are active components in antibiotic drugs frequently used in Sweden. For screening investigations using collection of wipe samples, good or acceptable performance was obtained for ten substances on three or more surface materials. Although not fully acceptable, useful performance for screening purposes was also obtained on the other surface materials and for the other substances, except Demeclocyklin HCl, on all surface materials. By employing a classification procedure, where the samples are divided into groups according to increasing contamination of the sample surfaces, screening samples and the contamination level can simply be compared. This classification procedure will also help to circumvent any deficiency in recovery performance for some substances and surface materials.

 

Place, publisher, year, edition, pages
ASTM International, 2011
Keywords
antibiotics, HPLC-MS/MS, leakage, occupational exposure, screening, spill, surface contamination, wipe sampling
Identifiers
urn:nbn:se:umu:diva-42415 (URN)10.1520/JAI103544 (DOI)
Available from: 2011-04-07 Created: 2011-04-07 Last updated: 2018-06-08Bibliographically approved
Nygren, O. & Lindahl, R. (2011). Screening of spill and leakage of antibiotics in hospital wards. Journal of ASTM International, 8(6), 24
Open this publication in new window or tab >>Screening of spill and leakage of antibiotics in hospital wards
2011 (English)In: Journal of ASTM International, ISSN 1546-962X, E-ISSN 1546-962X, Vol. 8, no 6, p. 24-Article in journal (Refereed) Published
Abstract [en]

This paper presents a two-phase study of spill and leakage of antibiotics in hospitals. The first phase was a screening of spill and leakage at 21 hospital wards in 16 hospitals. Phase two was an extended investigation, where different measures to reduce spill and leakage were implemented and a follow-up screening was made to evaluate the effect of the measures. At the screening, 206 samples were collected. The result was used to classify the wards into four classes: Low, Mean, High, and Very high. Spatial distribution patterns and the effect of compounding systems were also investigated. The screening showed that spill and leakage occur at all wards. Eleven of the 21 wards had High or Very high contamination level. This result also showed that the substances were distributed according to three possible patterns. The compounding systems also had an impact on the spill and leakage. All four wards that used a closed system were found among the six wards with the lowest spill and leakage, while all three wards that used open venting systems were found among the six wards with the highest spill and leakage. The result also showed that it is possible to handle antibiotics with only insignificant spill and leakage, i.e., by using closed systems. Three wards, classified as Very high, were included in the second phase. Measures to decrease spill and leakage and reduce the distribution the substances were implemented. After two month, a follow-up screening was carried out. The result showed lower contamination levels at all three wards and the implemented measures had some effect. Simple and easy-to-do measures can contribute to reduce the spill and leakage that occur. There is still, however, a need to discuss how to handle antibiotics in a safe way to reduce possible spill and leakage and to prevent the distribution of this spill and leakage.

Place, publisher, year, edition, pages
ASTM International, 2011
Keywords
antibiotics, compounding, hospital wards, leakage, occupational exposure, screening, spill, surface contamination, wipe sampling
Identifiers
urn:nbn:se:umu:diva-42416 (URN)10.1520/JAI103453 (DOI)
Available from: 2011-04-07 Created: 2011-04-07 Last updated: 2018-06-08Bibliographically approved
Nygren, O. (2010). Development of a method for screening spill and leakage of antibiotics on surfaces based on wipe sampling and HPLC-MS/MS analysis. Paper presented at ASTM D22.4 Symposium on Surface and Dermal Sampling. San Antonio, Texas, USA.
Open this publication in new window or tab >>Development of a method for screening spill and leakage of antibiotics on surfaces based on wipe sampling and HPLC-MS/MS analysis
2010 (English)Conference paper, Published paper (Other academic)
National Category
Chemical Sciences
Identifiers
urn:nbn:se:umu:diva-42443 (URN)
Conference
ASTM D22.4 Symposium on Surface and Dermal Sampling. San Antonio, Texas, USA
Note
ASTM D22.4 Symposium on Surface and Dermal Sampling 14-15 October 2010, San Antonio, Texas, USAAvailable from: 2011-04-07 Created: 2011-04-07 Last updated: 2018-06-08Bibliographically approved
Nygren, O. (2010). Development of a method for screening spill and leakage of antibiotics on surfaces based on wipe sampling and HPLC-MS/MS analysis. In: : . Paper presented at ASTM D22.4 Symposium on Surface and Dermal Sampling 14-15 October 2010, San Antonio, Texas, USA.
Open this publication in new window or tab >>Development of a method for screening spill and leakage of antibiotics on surfaces based on wipe sampling and HPLC-MS/MS analysis
2010 (English)Conference paper, Published paper (Other academic)
National Category
Chemical Sciences
Identifiers
urn:nbn:se:umu:diva-66759 (URN)
Conference
ASTM D22.4 Symposium on Surface and Dermal Sampling 14-15 October 2010, San Antonio, Texas, USA
Available from: 2013-03-05 Created: 2013-03-05 Last updated: 2018-06-08Bibliographically approved
Organisations

Search in DiVA

Show all publications