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Boraxbekk, Carl-JohanORCID iD iconorcid.org/0000-0002-4458-6475
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Publications (10 of 104) Show all publications
Sandberg, P., Boraxbekk, C.-J., Zogaj, I. & Nyberg, L. (2023). Age-independent transfer after successful associative mnemonic training. Journal of Cognitive Enhancement, 7(3-4), 159-172
Open this publication in new window or tab >>Age-independent transfer after successful associative mnemonic training
2023 (English)In: Journal of Cognitive Enhancement, ISSN 2509-3290, Vol. 7, no 3-4, p. 159-172Article in journal (Refereed) Published
Abstract [en]

Generalization of training to support the performance on new tasks—transfer—has been much studied. One hypothesis is that transfer occurs if overlapping neuronal circuits are engaged in both training and transfer tasks. Here, we investigated transfer effects in the domain of episodic memory by following 356 participants between 20 and 83 years who downloaded and used a smart phone application to practice the method of loci (MoL) over 3 months. We measured transfer of MoL training to three associative memory tasks with hypothesized neurocognitive overlap (binding in the hippocampus) with the trained task. Transfer tasks were administered at the beginning of training and when two specific proficiency levels in Loci training were reached. Results showed robust transfer effects across the age span at both levels. These results indicate that app-based strategy training can lead to enhancement of episodic memory beyond the specific training task, which may have clinical implementations.

Place, publisher, year, edition, pages
Springer Nature, 2023
Keywords
Aging, Episodic memory training, Mnemonics, Strategy training, The method of loci, Transfer effects
National Category
Neurosciences
Identifiers
urn:nbn:se:umu:diva-215935 (URN)10.1007/s41465-023-00273-y (DOI)001087509300001 ()2-s2.0-85174607278 (Scopus ID)
Funder
Knut and Alice Wallenberg Foundation, 2015.0277
Available from: 2023-11-02 Created: 2023-11-02 Last updated: 2024-01-11Bibliographically approved
Demnitz, N., Hulme, O. J., Siebner, H. R., Kjaer, M., Ebmeier, K. P., Boraxbekk, C.-J. & Gillan, C. M. (2023). Characterising the covariance pattern between lifestyle factors and structural brain measures: a multivariable replication study of two independent ageing cohorts. Neurobiology of Aging, 131, 115-123
Open this publication in new window or tab >>Characterising the covariance pattern between lifestyle factors and structural brain measures: a multivariable replication study of two independent ageing cohorts
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2023 (English)In: Neurobiology of Aging, ISSN 0197-4580, E-ISSN 1558-1497, Vol. 131, p. 115-123Article in journal (Refereed) Published
Abstract [en]

Modifiable lifestyle factors have been shown to promote healthy brain ageing. However, studies have typically focused on a single factor at a time. Given that lifestyle factors do not occur in isolation, multivariable analyses provide a more realistic model of the lifestyle-brain relationship. Here, canonical correlation analyses (CCA) examined the relationship between nine lifestyle factors and seven MRI-derived indices of brain structure. The resulting covariance pattern was further explored with Bayesian regressions. CCA analyses were first conducted on a Danish cohort of older adults (n = 251) and then replicated in a British cohort (n = 668). In both cohorts, the latent factors of lifestyle and brain structure were positively correlated (UK: r =.37, p < 0.001; Denmark: r =.27, p < 0.001). In the cross-validation study, the correlation between lifestyle-brain latent factors was r =.10, p = 0.008. However, the pattern of associations differed between datasets. These findings suggest that baseline characterisation and tailoring towards the study sample may be beneficial for achieving targeted lifestyle interventions.

Place, publisher, year, edition, pages
Elsevier, 2023
Keywords
Magnetic resonance imaging (MRI), Modifiable lifestyle factors, Old age, White matter hyperintensities
National Category
Geriatrics
Identifiers
urn:nbn:se:umu:diva-214977 (URN)10.1016/j.neurobiolaging.2023.07.023 (DOI)37619515 (PubMedID)2-s2.0-85172425623 (Scopus ID)
Funder
Novo Nordisk Foundation, NNF20OC0064869EU, Horizon 2020, 732592
Available from: 2023-10-16 Created: 2023-10-16 Last updated: 2023-10-16Bibliographically approved
Ryberg, M., Boraxbekk, C.-J., Kjaer, M. & Demnitz, N. (2023). Effects of acute physical activity on brain metabolites as measured by magnetic resonance spectroscopy (1H-MRS) in humans: a systematic review. Heliyon, 9(10), Article ID e20534.
Open this publication in new window or tab >>Effects of acute physical activity on brain metabolites as measured by magnetic resonance spectroscopy (1H-MRS) in humans: a systematic review
2023 (English)In: Heliyon, E-ISSN 2405-8440, Vol. 9, no 10, article id e20534Article in journal (Refereed) Published
Abstract [en]

Physical activity (PA) promotes brain health in a variety of domains including cognition, mood, and neuroplasticity. At the neurochemical level, the mechanisms underlying these effects in the brain are not fully understood. With proton Magnetic Resonance Spectroscopy (1H-MRS), it is possible to non-invasively quantify metabolite concentrations, enabling studies to obtain measures of exercise-induced neurochemical changes. This systematic review aimed to examine the existing literature on acute effects of PA on brain metabolites as measured by 1H-MRS. Four databases (Cochrane Central Register of Controlled Trials, PubMed, Embase, and PsycINFO) were searched, identifying 2965 studies, of which 9 met the inclusion criteria. Across studies, Gamma-AminoButyric Acid (GABA) and lactate tended to increase after exercise, while no significant changes in choline were reported. For glutamine/glutamate (Glx), studies were inconclusive. Conclusions were limited by the lack of consensus on 1H-MRS data processing and exercise protocols. To reduce inter-study differences, future studies are recommended to: (1) apply a standardized exercise index, (2) consider the onset time of MRS scans, and (3) follow standardized MRS quantification methods.

Place, publisher, year, edition, pages
Elsevier, 2023
Keywords
Spectroscopy, Exercise, Neurochemistry, Interventions
National Category
Neurosciences
Identifiers
urn:nbn:se:umu:diva-218224 (URN)10.1016/j.heliyon.2023.e20534 (DOI)001088294100001 ()37818016 (PubMedID)2-s2.0-85173660640 (Scopus ID)
Available from: 2023-12-18 Created: 2023-12-18 Last updated: 2023-12-18Bibliographically approved
Simonsson, E., Levik Sandström, S., Hedlund, M., Holmberg, H., Johansson, B., Lindelöf, N., . . . Rosendahl, E. (2023). Effects of controlled supramaximal high-intensity interval training on cardiorespiratory fitness and global cognitive function in older adults: the Umeå hit study-a randomized controlled trial. The journals of gerontology. Series A, Biological sciences and medical sciences, 78(9), 1581-1590
Open this publication in new window or tab >>Effects of controlled supramaximal high-intensity interval training on cardiorespiratory fitness and global cognitive function in older adults: the Umeå hit study-a randomized controlled trial
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2023 (English)In: The journals of gerontology. Series A, Biological sciences and medical sciences, ISSN 1079-5006, E-ISSN 1758-535X, Vol. 78, no 9, p. 1581-1590Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: This study examined the effects of regulated and controlled supramaximal high-intensity interval training (HIT) adapted for older adults, compared to moderate-intensity training (MIT), on cardiorespiratory fitness; cognitive, cardiovascular, and muscular function; and quality of life.

METHODS: Sixty-eight nonexercising older adults (66-79 years, 44% males) were randomized to 3 months of twice-weekly HIT (20-minute session including 10 × 6-second intervals) or MIT (40-minute session including 3 × 8-minute intervals) on stationary bicycles in an ordinary gym setting. Individualized target intensity was watt controlled with a standardized pedaling cadence and individual adjustment of the resistance load. Primary outcomes were cardiorespiratory fitness (V̇o2peak) and global cognitive function (unit-weighted composite).

RESULTS: V̇o2peak increased significantly (mean 1.38 mL/kg/min, 95% CI [0.77, 1.98]), with no between-group difference (mean difference 0.05 [-1.17, 1.25]). Global cognition did not improve (0.02 [-0.05, 0.09]), nor differed between groups (0.11 [-0.03, 0.24]). Significant between-group differences in change were observed for working memory (0.32 [0.01, 0.64]), and maximal isometric knee extensor muscle strength (0.07 N·m/kg [0.003, 0.137]), both in favor of HIT. Irrespective of the group, there was a negative change in episodic memory (-0.15 [-0.28, -0.02]), a positive change in visuospatial ability (0.26 [0.08, 0.44]), and a decrease in systolic (-2.09 mmHg [-3.54, -0.64]) and diastolic (-1.27 mmHg [-2.31, -0.25]) blood pressure.

CONCLUSIONS: In nonexercising older adults, 3 months of watt-controlled supramaximal HIT improved cardiorespiratory fitness and cardiovascular function to a similar extent as MIT, despite half the training time. In favor of HIT, there was an improvement in muscular function and a potential domain-specific effect on working memory.

CLINICAL TRIAL REGISTRATION: NCT03765385.

Place, publisher, year, edition, pages
Oxford University Press, 2023
Keywords
Aerobic capacity, HIIT, Moderate-intensity training, SIT, Sprint interval training
National Category
Sport and Fitness Sciences
Identifiers
urn:nbn:se:umu:diva-214207 (URN)10.1093/gerona/glad070 (DOI)000959356800001 ()36972981 (PubMedID)2-s2.0-85169177109 (Scopus ID)
Funder
Swedish Research Council, 2017-00912Forte, Swedish Research Council for Health, Working Life and Welfare, 2020-00159The Kamprad Family FoundationThe Dementia Association - The National Association for the Rights of the DementedFoundation for the Memory of Ragnhild and Einar LundströmThe Kempe FoundationsUmeå University
Available from: 2023-09-08 Created: 2023-09-08 Last updated: 2023-09-08Bibliographically approved
Stiernman, L., Dubol, M., Comasco, E., Sundström-Poromaa, I., Boraxbekk, C.-J., Johansson, I.-M. & Bixo, M. (2023). Emotion-induced brain activation across the menstrual cycle in individuals with premenstrual dysphoric disorder and associations to serum levels of progesterone-derived neurosteroids. Translational Psychiatry, 13(1), Article ID 124.
Open this publication in new window or tab >>Emotion-induced brain activation across the menstrual cycle in individuals with premenstrual dysphoric disorder and associations to serum levels of progesterone-derived neurosteroids
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2023 (English)In: Translational Psychiatry, E-ISSN 2158-3188, Vol. 13, no 1, article id 124Article in journal (Refereed) Published
Abstract [en]

Premenstrual dysphoric disorder (PMDD) is a debilitating disorder characterized by severe mood symptoms in the luteal phase of the menstrual cycle. PMDD symptoms are hypothesized to be linked to an altered sensitivity to normal luteal phase levels of allopregnanolone (ALLO), a GABAA-modulating progesterone metabolite. Moreover, the endogenous 3β-epimer of ALLO, isoallopregnanolone (ISO), has been shown to alleviate PMDD symptoms through its selective and dose-dependent antagonism of the ALLO effect. There is preliminary evidence showing altered recruitment of brain regions during emotion processing in PMDD, but whether this is associated to serum levels of ALLO, ISO or their relative concentration is unknown. In the present study, subjects with PMDD and asymptomatic controls underwent functional magnetic resonance imaging (fMRI) in the mid-follicular and the late-luteal phase of the menstrual cycle. Brain responses to emotional stimuli were investigated and related to serum levels of ovarian steroids, the neurosteroids ALLO, ISO, and their ratio ISO/ALLO. Participants with PMDD exhibited greater activity in brain regions which are part of emotion-processing networks during the late-luteal phase of the menstrual cycle. Furthermore, activity in key regions of emotion processing networks - the parahippocampal gyrus and amygdala - was differentially associated to the ratio of ISO/ALLO levels in PMDD subjects and controls. Specifically, a positive relationship between ISO/ALLO levels and brain activity was found in PMDD subjects, while the opposite was observed in controls. In conclusion, individuals with PMDD show altered emotion-induced brain responses in the late-luteal phase of the menstrual cycle which may be related to an abnormal response to physiological levels of GABAA-active neurosteroids.

Place, publisher, year, edition, pages
Springer Nature, 2023
National Category
Psychiatry
Identifiers
urn:nbn:se:umu:diva-206958 (URN)10.1038/s41398-023-02424-3 (DOI)000968319200001 ()37055419 (PubMedID)2-s2.0-85152386545 (Scopus ID)
Available from: 2023-04-26 Created: 2023-04-26 Last updated: 2024-03-18Bibliographically approved
Nyberg, L., Andersson, M., Lundquist, A., Baaré, W. F. .., Bartrés-Faz, D., Bertram, L., . . . Walhovd, K. B. (2023). Individual differences in brain aging: heterogeneity in cortico-hippocampal but not caudate atrophy rates. Cerebral Cortex, 33(9), 5075-5081
Open this publication in new window or tab >>Individual differences in brain aging: heterogeneity in cortico-hippocampal but not caudate atrophy rates
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2023 (English)In: Cerebral Cortex, ISSN 1047-3211, E-ISSN 1460-2199, Vol. 33, no 9, p. 5075-5081Article in journal (Refereed) Published
Abstract [en]

It is well documented that some brain regions, such as association cortices, caudate, and hippocampus, are particularly prone to age-related atrophy, but it has been hypothesized that there are individual differences in atrophy profiles. Here, we document heterogeneity in regional-atrophy patterns using latent-profile analysis of 1,482 longitudinal magnetic resonance imaging observations. The results supported a 2-group solution reflecting differences in atrophy rates in cortical regions and hippocampus along with comparable caudate atrophy. The higher-atrophy group had the most marked atrophy in hippocampus and also lower episodic memory, and their normal caudate atrophy rate was accompanied by larger baseline volumes. Our findings support and refine models of heterogeneity in brain aging and suggest distinct mechanisms of atrophy in striatal versus hippocampal-cortical systems.

Place, publisher, year, edition, pages
Oxford University Press, 2023
Keywords
aging, individual differences, caudate, hippocampus, cortex
National Category
Neurosciences
Research subject
Medicine
Identifiers
urn:nbn:se:umu:diva-201287 (URN)10.1093/cercor/bhac400 (DOI)000863898100001 ()36197324 (PubMedID)2-s2.0-85159256770 (Scopus ID)
Funder
Knut and Alice Wallenberg FoundationEU, Horizon 2020, 732592
Available from: 2022-11-27 Created: 2022-11-27 Last updated: 2023-06-07Bibliographically approved
Demnitz, N., Gates, A. T., Mortensen, E. L., Garde, E., Wimmelmann, C. L., Siebner, H. R., . . . Boraxbekk, C.-J. (2023). Is it all in the baseline? Trajectories of chair stand performance over 4 years and their association with grey matter structure in older adults. Human Brain Mapping, 44(11), 4299-4309
Open this publication in new window or tab >>Is it all in the baseline? Trajectories of chair stand performance over 4 years and their association with grey matter structure in older adults
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2023 (English)In: Human Brain Mapping, ISSN 1065-9471, E-ISSN 1097-0193, Vol. 44, no 11, p. 4299-4309Article in journal (Refereed) Published
Abstract [en]

Understanding individual variability in response to physical activity is key to developing more effective and personalised interventions for healthy ageing. Here, we aimed to unpack individual differences by using longitudinal data from a randomised-controlled trial of a 12-month muscle strengthening intervention in older adults. Physical function of the lower extremities was collected from 247 participants (66.3 ± 2.5 years) at four time-points. At baseline and at year 4, participants underwent 3 T MRI brain scans. K-means longitudinal clustering was used to identify patterns of change in chair stand performance over 4 years, and voxel-based morphometry was applied to map structural grey matter volume at baseline and year 4. Results identified three groups showing trajectories of poor (33.6%), mid (40.1%), and high (26.3%) performance. Baseline physical function, sex, and depressive symptoms significantly differed between trajectory groups. High performers showed greater grey matter volume in the motor cerebellum compared to the poor performers. After accounting for baseline chair stand performance, participants were re-assigned to one of four trajectory-based groups: moderate improvers (38.9%), maintainers (38.5%), improvers (13%), and decliners (9.7%). Clusters of significant grey matter differences were observed between improvers and decliners in the right supplementary motor area. Trajectory-based group assignments were unrelated to the intervention arms of the study. In conclusion, patterns of change in chair stand performance were associated with greater grey matter volumes in cerebellar and cortical motor regions. Our findings emphasise that how you start matters, as baseline chair stand performance was associated with cerebellar volume 4 years later.

Place, publisher, year, edition, pages
John Wiley & Sons, 2023
Keywords
ageing, longitudinal analysis, physical activity, physical function, VBM
National Category
Neurosciences Gerontology, specialising in Medical and Health Sciences
Identifiers
urn:nbn:se:umu:diva-209197 (URN)10.1002/hbm.26346 (DOI)000991689100001 ()37219945 (PubMedID)2-s2.0-85159866920 (Scopus ID)
Available from: 2023-06-09 Created: 2023-06-09 Last updated: 2023-11-06Bibliographically approved
Fjell, A. M., Sørensen, Ø., Wang, Y., Amlien, I. K., Baaré, W. F., Bartrés-Faz, D., . . . Walhovd, K. B. (2023). Is short sleep bad for the brain?: Brain structure and cognitive function in short sleepers. Journal of Neuroscience, 43(28), 5241-5250
Open this publication in new window or tab >>Is short sleep bad for the brain?: Brain structure and cognitive function in short sleepers
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2023 (English)In: Journal of Neuroscience, ISSN 0270-6474, E-ISSN 1529-2401, Vol. 43, no 28, p. 5241-5250Article in journal (Refereed) Published
Abstract [en]

Many sleep less than recommended without experiencing daytime sleepiness. According to prevailing views, short sleep increases risk of lower brain health and cognitive function. Chronic mild sleep deprivation could cause undetected sleep debt, negatively affecting cognitive function and brain health. However, it is possible that some have less sleep need and are more resistant to negative effects of sleep loss. We investigated this using a cross-sectional and longitudinal sample of 47,029 participants of both sexes (20-89 years) from the Lifebrain consortium, Human Connectome project (HCP) and UK Biobank (UKB), with measures of self-reported sleep, including 51,295 MRIs of the brain and cognitive tests. A total of 740 participants who reported to sleep <6 h did not experience daytime sleepiness or sleep problems/disturbances interfering with falling or staying asleep. These short sleepers showed significantly larger regional brain volumes than both short sleepers with daytime sleepiness and sleep problems (n = 1742) and participants sleeping the recommended 7-8 h (n = 3886). However, both groups of short sleepers showed slightly lower general cognitive function (GCA), 0.16 and 0.19 SDs, respectively. Analyses using accelerometer-estimated sleep duration confirmed the findings, and the associations remained after controlling for body mass index, depression symptoms, income, and education. The results suggest that some people can cope with less sleep without obvious negative associations with brain morphometry and that sleepiness and sleep problems may be more related to brain structural differences than duration. However, the slightly lower performance on tests of general cognitive abilities warrants closer examination in natural settings.

SIGNIFICANCE STATEMENT: Short habitual sleep is prevalent, with unknown consequences for brain health and cognitive performance. Here, we show that daytime sleepiness and sleep problems are more strongly related to regional brain volumes than sleep duration. However, participants sleeping ≤6 h had slightly lower scores on tests of general cognitive function (GCA). This indicates that sleep need is individual and that sleep duration per se is very weakly if at all related brain health, while daytime sleepiness and sleep problems may show somewhat stronger associations. The association between habitual short sleep and lower scores on tests of general cognitive abilities must be further scrutinized in natural settings.

Keywords
brain, cognition, hippocampus, MRI, sleep, sleepiness
National Category
Neurosciences
Identifiers
urn:nbn:se:umu:diva-212215 (URN)10.1523/JNEUROSCI.2330-22.2023 (DOI)37365003 (PubMedID)2-s2.0-85164626158 (Scopus ID)
Funder
EU, Horizon 2020, 732592EU, European Research Council, 283634EU, European Research Council, 725025EU, European Research Council, 313440The Research Council of NorwayKnut and Alice Wallenberg FoundationEU, European Research Council, 677804Wellcome trust, 203139/Z/16/ZNIH (National Institutes of Health)
Available from: 2023-07-21 Created: 2023-07-21 Last updated: 2023-07-21Bibliographically approved
Binnewies, J., Nawijn, L., Brandmaier, A. M., Baaré, W. F. .., Boraxbekk, C.-J., Demnitz, N., . . . Penninx, B. W. .. (2023). Lifestyle-related risk factors and their cumulative associations with hippocampal and total grey matter volume across the adult lifespan: a pooled analysis in the European Lifebrain consortium. Brain Research Bulletin, 200, Article ID 110692.
Open this publication in new window or tab >>Lifestyle-related risk factors and their cumulative associations with hippocampal and total grey matter volume across the adult lifespan: a pooled analysis in the European Lifebrain consortium
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2023 (English)In: Brain Research Bulletin, ISSN 0361-9230, E-ISSN 1873-2747, Vol. 200, article id 110692Article in journal (Refereed) Published
Abstract [en]

Background: Lifestyle-related risk factors, such as obesity, physical inactivity, short sleep, smoking and alcohol use, have been associated with low hippocampal and total grey matter volumes (GMV). However, these risk factors have mostly been assessed as separate factors, leaving it unknown if variance explained by these factors is overlapping or additive. We investigated associations of five lifestyle-related factors separately and cumulatively with hippocampal and total GMV, pooled across eight European cohorts.

Methods: We included 3838 participants aged 18–90 years from eight cohorts of the European Lifebrain consortium. Using individual person data, we performed cross-sectional meta-analyses on associations of presence of lifestyle-related risk factors separately (overweight/obesity, physical inactivity, short sleep, smoking, high alcohol use) as well as a cumulative unhealthy lifestyle score (counting the number of present lifestyle-related risk factors) with FreeSurfer-derived hippocampal volume and total GMV. Lifestyle-related risk factors were defined according to public health guidelines.

Results: High alcohol use was associated with lower hippocampal volume (r = −0.10, p = 0.021), and overweight/obesity with lower total GMV (r = −0.09, p = 0.001). Other lifestyle-related risk factors were not significantly associated with hippocampal volume or GMV. The cumulative unhealthy lifestyle score was negatively associated with total GMV (r = −0.08, p = 0.001), but not hippocampal volume (r = −0.01, p = 0.625).

Conclusions: This large pooled study confirmed the negative association of some lifestyle-related risk factors with hippocampal volume and GMV, although with small effect sizes. Lifestyle factors should not be seen in isolation as there is evidence that having multiple unhealthy lifestyle factors is associated with a linear reduction in overall brain volume.

Place, publisher, year, edition, pages
Elsevier, 2023
Keywords
Alcohol, Brain structure, Obesity, Physical activity, Sleep, Smoking
National Category
Neurosciences
Identifiers
urn:nbn:se:umu:diva-211986 (URN)10.1016/j.brainresbull.2023.110692 (DOI)37336327 (PubMedID)2-s2.0-85163160957 (Scopus ID)
Funder
EU, Horizon 2020, 732592Knut and Alice Wallenberg FoundationWellcome trust, 216462/Z/19/ZEU, European Research Council, 283634EU, European Research Council, 313440EU, European Research Council, 725025The Research Council of Norway
Available from: 2023-07-12 Created: 2023-07-12 Last updated: 2023-07-12Bibliographically approved
Lövdén, M., Pagin, A., Bartrés-Faz, D., Boraxbekk, C.-J., Brandmaier, A. M., Demnitz, N., . . . Nyberg, L. (2023). No moderating influence of education on the association between changes in hippocampus volume and memory performance in aging. Aging Brain, 4, Article ID 100082.
Open this publication in new window or tab >>No moderating influence of education on the association between changes in hippocampus volume and memory performance in aging
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2023 (English)In: Aging Brain, ISSN 2589-9589, Vol. 4, article id 100082Article in journal (Refereed) Published
Abstract [en]

Contemporary accounts of factors that may modify the risk for age-related neurocognitive disorders highlight education and its contribution to a cognitive reserve. By this view, individuals with higher educational attainment should show weaker associations between changes in brain and cognition than individuals with lower educational attainment. We tested this prediction in longitudinal data on hippocampus volume and episodic memory from 708 middle-aged and older individuals using local structural equation modeling. This technique does not require categorization of years of education and does not constrain the shape of relationships, thereby maximizing the chances of revealing an effect of education on the hippocampus-memory association. The results showed that the data were plausible under the assumption that there was no influence of education on the association between change in episodic memory and change in hippocampus volume. Restricting the sample to individuals with elevated genetic risk for dementia (APOE ε4 carriers) did not change these results. We conclude that the influence of education on changes in episodic memory and hippocampus volume is inconsistent with predictions by the cognitive reserve theory.

Place, publisher, year, edition, pages
Elsevier, 2023
Keywords
Cognitive reserve, Brain maintenance, Hippocampus, Memory, Aging
National Category
Psychology (excluding Applied Psychology)
Identifiers
urn:nbn:se:umu:diva-218223 (URN)10.1016/j.nbas.2023.100082 (DOI)
Funder
EU, Horizon 2020, 732592EU, European Research Council, 283634EU, European Research Council, 725025EU, European Research Council, 313440The Research Council of Norway
Available from: 2023-12-18 Created: 2023-12-18 Last updated: 2023-12-18Bibliographically approved
Projects
Be smart exercise your heart: Using PET/CT to study physical exercise effects on the dopaminergic system in relation to aging and cognition [2012-00530_VR]; Umeå University
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0002-4458-6475

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