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Stenberg, Berndt
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Publications (10 of 71) Show all publications
Engfeldt, M., Isaksson, M., Glas, B., Hagvall, L., Löfnertz Petersson, A., Matura, M., . . . Bruze, M. (2019). Patch Testing with a New Composition of Mercapto Mix: A Multi-centre Study by the Swedish Contact Dermatitis Research Group. Acta Dermato-Venereologica, 99(11), 960-963
Open this publication in new window or tab >>Patch Testing with a New Composition of Mercapto Mix: A Multi-centre Study by the Swedish Contact Dermatitis Research Group
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2019 (English)In: Acta Dermato-Venereologica, ISSN 0001-5555, E-ISSN 1651-2057, Vol. 99, no 11, p. 960-963Article in journal (Refereed) Published
Abstract [en]

This study investigated whether more patients with contact allergies were detected by patch testing with mercapto mix with a higher concentration of 2-mercaptobenzothiazolinone (MBT) than the commonly used mercapto mix. A total of 3,143 dermatitis patients in 5 Swedish dermatology departments were patch-tested with 3 mercapto test preparations: MBT 2.0% petrolatum (pet.); mercapto mix 2.0% pet.; and mercapto mix 3.5% pet. Positive reactions to these mercapto mixes varied between 0-0.50%, 0-0.93%, and 0-1.4%, respectively, in the 5 centres. Numerically, mercapto mix 3.5% pet. detected all positive patients and more patch-test positive patients than did the 2 other substances, but the difference was not statistically significant. The authors recommend replacing mercapto mix 2.0% pet. in the Swedish baseline series with mercapto mix 3.5% pet., since the latter also detected those patients who would have been missed because MBT 2.0% is not included in the Swedish baseline series.

Place, publisher, year, edition, pages
Acta Dermato-Venereologica, 2019
Keywords
allergic contact dermatitis, contact allergy, 2-mercaptobenzothiazole, mercapto mix, rubber, delayed hypersensitivity
National Category
Dermatology and Venereal Diseases
Identifiers
urn:nbn:se:umu:diva-164037 (URN)10.2340/00015555-3249 (DOI)000487762500003 ()31240321 (PubMedID)
Available from: 2019-10-16 Created: 2019-10-16 Last updated: 2019-10-16Bibliographically approved
Mårell, L., Bergdahl, J., Tillberg, A., Stenberg, B. & Berglund, A. (2019). Psychological symptoms and self-image of patients with complaints attributed to dental restorative materials. Clinical Oral Investigations, 23(6), 2805-2811
Open this publication in new window or tab >>Psychological symptoms and self-image of patients with complaints attributed to dental restorative materials
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2019 (English)In: Clinical Oral Investigations, ISSN 1432-6981, E-ISSN 1436-3771, Vol. 23, no 6, p. 2805-2811Article in journal (Refereed) Published
Abstract [en]

Objectives: The aim was to study self-image and the level of psychological symptoms in patients with symptoms attributed to their dental restorative materials.

Materials and methods: A questionnaire containing questions regarding dental and medical history was answered by 257 participants, one group with local oral symptoms only (LSO), and one group with multi-symptoms (M-S). A reference group was randomly selected from a research database at the Department of Psychology, Umeå University, Sweden. The self-image was assessed using the Structural Analysis of Social Behavior (SASB). Psychological symptoms such as somatization, depression, and anxiety were assessed using the Symptom Check List 90 (SCL-90) and the Global Severity Index (GSI) was used to determine the level of psychological symptoms.

Results: SASB showed that the M-S group and the LSO-group scored significantly higher on the Bspontaneous^ and Bpositive self-image^ than the reference group. In the SCL-90, the M-S group scored significantly higher than the LSO-group and the references on the somatization subscales. On depression, anxiety, and the GSI scale, the M-S group scored significantly higher than the reference group.

Conclusions: The two subgroups scored significantly higher on the SASB Spontaneous and Positive clusters which indicates that these patients have an excessively positive self-image, are very spontaneous and have an overconfidence in themselves compared to the reference group. In the M-S group there was a clear tendency to somatization, depression, and anxiety and they were more psychologically stressed than the reference group.

Clinical relevance: Among the patients with illness attributed to their dental materials, the M-S-patients had a significantly higher level of general psychological distress and somatization than the control group which may lead to mental stress.

Place, publisher, year, edition, pages
Springer Berlin/Heidelberg, 2019
Keywords
Dental materials, Environmental intolerance, SASB, SCL-90
National Category
Biomaterials Science Dentistry
Research subject
Odontology
Identifiers
urn:nbn:se:umu:diva-114092 (URN)10.1007/s00784-018-2707-4 (DOI)000467444800026 ()30368660 (PubMedID)
Note

Originally included in thesis in manuscript form with titel "Psychological symptoms and self-image of patients with complaints attributed to dental restorative materials: Psychological symptoms in patients with environmental intolerance".

Available from: 2016-01-13 Created: 2016-01-13 Last updated: 2019-06-17Bibliographically approved
Hagvall, L., Bruze, M., Engfeldt, M., Isaksson, M., Lindberg, M., Ryberg, K., . . . Christensson, J. B. (2018). Contact allergy to oxidized geraniol among Swedish dermatitis patients: a multicentre study by the Swedish Contact Dermatitis Research Group. Contact Dermatitis, 79(4), 232-238
Open this publication in new window or tab >>Contact allergy to oxidized geraniol among Swedish dermatitis patients: a multicentre study by the Swedish Contact Dermatitis Research Group
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2018 (English)In: Contact Dermatitis, ISSN 0105-1873, E-ISSN 1600-0536, Vol. 79, no 4, p. 232-238Article in journal (Refereed) Published
Abstract [en]

Background: Geraniol is a widely used fragrance terpene, and is included in fragrance mix I. Geraniol is prone to autoxidation, forming the skin sensitizers geranial, neral, and geraniol-7-hydroperoxide. Oxidized geraniol has previously been patch tested in 1 clinic, giving 1% to 4.6% positive reactions in consecutive patients when tested at 2% to 11%.

Aim: To compare test reactions to pure and oxidized geraniol, to compare 2 different test concentrations of oxidized geraniol and to investigate the pattern of concomitant reactions to fragrance markers of the baseline series in a multicentre setting.

Methods: One thousand four hundred and seventy-six consecutive patients referred for patch testing were patch tested with geraniol 6% pet. and oxidized geraniol 6% and 11% pet. Results: Pure geraniol 6% pet., oxidized geraniol 6% pet. and oxidized geraniol 11% pet. gave 1%, 3% and 8% positive patch test reactions and 0.7%, 3% and 5% doubtful reactions, respectively. Approximately 50% of the patients with doubtful reactions to oxidized geraniol 6% pet. had positive reactions to oxidized geraniol 11% pet.

Conclusions: Oxidized geraniol 11% pet. provides better detection than oxidized geraniol 6% pet. As most patients reacted only to oxidized geraniol, it is important to explore further whether oxidized geraniol should be included in a baseline patch test series.

Place, publisher, year, edition, pages
John Wiley & Sons, 2018
Keywords
allergic contact dermatitis, autoxidation, fragrance contact allergy, fragrance mix I, geraniol, patch sting, terpenes
National Category
Dermatology and Venereal Diseases
Identifiers
urn:nbn:se:umu:diva-152196 (URN)10.1111/cod.13047 (DOI)000443805100006 ()29926925 (PubMedID)
Available from: 2018-10-31 Created: 2018-10-31 Last updated: 2018-10-31Bibliographically approved
Khatami, A., Emmelin, M., Talaee, R., Mohammadi, A. M., Aghazadeh, N., Firooz, A. & Stenberg, B. (2018). Lived experiences of patients suffering from acute Old World cutaneous leishmaniasis: A qualitative content analysis study from Iran. Iranian Journal of Arthropod-Borne Diseases, 12(2), 180-195
Open this publication in new window or tab >>Lived experiences of patients suffering from acute Old World cutaneous leishmaniasis: A qualitative content analysis study from Iran
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2018 (English)In: Iranian Journal of Arthropod-Borne Diseases, ISSN 1735-7179, E-ISSN 2008-2517, Vol. 12, no 2, p. 180-195Article in journal (Refereed) Published
Abstract [en]

Background: The aim of this study was to explore the experiences of patients who suffer from acute cutaneous leishmaniasis in Iran, focusing on quality of life.

Methods: The study was conducted at two different sites in Iran in 2010–2011. Individual in-depth interviews were conducted with six men and six women parasitologically confirmed acute cutaneous leishmaniasis. Interviews were recorded, transcribed verbatim, and translated into English. Qualitative content analysis was used for data analysis.

Results: The participants, aged 23 to 63yr, had mild to severe disease. Based on the analysis four main themes were developed. "Fearing an agonizing disease" reflects patients' experiences of disease development resulting in sadness and depression, "struggling to cope" and "taking on the blame" both illustrate how patients experience living with the disease, which included both felt and enacted stigma as major social concerns. "Longing for being seen and heard" refers to patients' experiences with healthcare as well as their expectations and demands from communities and healthcare to be involved in closing the knowledge and awareness gap.

Conclusion: Mental and social dimensions of cutaneous leishmaniasis were complex and adversely affected patients' lives by causing psychological burden and limiting their social interactions. Health authorities have to plan programs to increase the disease awareness to prevent the existing stigma to improve patients' social condition and medical care.

Keywords
Cutaneous leishmaniasis, Qualitative research, Quality of life
National Category
Public Health, Global Health, Social Medicine and Epidemiology Dermatology and Venereal Diseases
Identifiers
urn:nbn:se:umu:diva-150629 (URN)
Available from: 2018-08-15 Created: 2018-08-15 Last updated: 2019-05-22Bibliographically approved
Engfeldt, M., Hagvall, L., Isaksson, M., Matura, M., Mowitz, M., Ryberg, K., . . . Bruze, M. (2017). Patch testing with hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) - a multicentre study of the Swedish Contact Dermatitis Research Group. Contact Dermatitis, 76(1), 34-39
Open this publication in new window or tab >>Patch testing with hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) - a multicentre study of the Swedish Contact Dermatitis Research Group
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2017 (English)In: Contact Dermatitis, ISSN 0105-1873, E-ISSN 1600-0536, Vol. 76, no 1, p. 34-39Article in journal (Refereed) Published
Abstract [en]

Background. In 2014, the fragrance hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) was excluded from the Swedish baseline series. Objectives. To study (i) whether fragrance mix (FM) II with 5% HICC detects more positive reactions than usual FM II with 2.5% HICC, and (ii) the reproducibility of patch testing with HICC. Methods. Two thousand one hundred and eighteen dermatitis patients at five Swedish dermatology departments were consecutively tested with FM II 14% pet., FM II 16.5% pet., and duplicate preparations of HICC 5% pet. Results. Of the patients, 3.2% reacted to FMII 14%, and 1.5% reacted to HICC. Separate testing with HICC detected 0.3% reactions without concomitant reactivity to FM II. FM II with 5% HICC did not give rise to more irritant reactions or signs of active sensitization than FM II with 2.5% HICC. Patch testing with duplicate applications of HICC increased the overall prevalence of HICC contact allergy to 1.9%. Conclusion. FMII with5% HICC does not detect more positive reactions than FMII with 2.5% HICC. Separate testing with HICC does not detect a sufficient proportion of patients who react only to HICC, without concomitant reactions to FMII, to warrant its inclusion in a baseline series.

Keywords
allergic contact dermatitis, contact allergy, delayed hypersensitivity, dose/area, fragrance, fragrance x II, high-performance liquid chromatography, hydroxyisohexyl 3-cyclohexene carboxaldehyde, CAS . 31906-04-4/51414-25-6
National Category
Dermatology and Venereal Diseases
Identifiers
urn:nbn:se:umu:diva-130994 (URN)10.1111/cod.12699 (DOI)000390785500005 ()
Available from: 2017-02-16 Created: 2017-02-16 Last updated: 2018-06-09Bibliographically approved
Carlsson, A., Svensson, Å., Anderson, C. D., Baranovskaya, I., Hindsén-Stenström, M., Holt, I., . . . Gånemo, A. (2017). Scoring of hand eczema: good reliability of hand eczema extent score. Acta Dermato-Venereologica, 97(2), 193-197
Open this publication in new window or tab >>Scoring of hand eczema: good reliability of hand eczema extent score
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2017 (English)In: Acta Dermato-Venereologica, ISSN 0001-5555, E-ISSN 1651-2057, Vol. 97, no 2, p. 193-197Article in journal (Refereed) Published
Abstract [en]

There is good agreement between dermatological staff and patients using the Hand Eczema Extent Score (HEES). The aim of this study was to assess inter- and intra-observer reliability of the HEES in dermatologists and intra-observer reliability of the HEES in patients with hand eczema. Six dermatologists assessed 18 patients twice. Only the hands of the patients were visible to the assessors. Patients performed a self-assessment twice. Inter- and intra-observer reliability was tested with intraclass correlation coefficient (ICC). The mean HEES score for all dermatologists' assessments was 21.0 (range 3.6-46.3). The corresponding mean scores for all patients' own assessments were 24.9 (range 4.0-54.0). Inter-observer reliability in the dermatologists' observations ICC classification was very good, median value 0.82 (range 0.56-0.92). The overall intra-observer reliability for the 6 dermatologists' ICC classification was very good (range 0.88-0.94). Intra-observer reliability in the patients' 2 self-assessments ICC classification was very good (ICC 0.95). In conclusion, HEES is a reliable tool for both dermatologists and patients to grade the extent of hand eczema.

Keywords
dermatitis, inter-observer reliability, intra-observer reliability, self-assessment, severity
National Category
Dermatology and Venereal Diseases
Identifiers
urn:nbn:se:umu:diva-127493 (URN)10.2340/00015555-2521 (DOI)000393895500006 ()27563701 (PubMedID)
Available from: 2016-11-14 Created: 2016-11-14 Last updated: 2018-06-09Bibliographically approved
Mörtzell Henriksson, M., Newman, E., Witt, V., Derfler, K., Leitner, G., Eloot, S., . . . Wahlström, A. (2016). Adverse events in apheresis: an update of the WAA registry data. Transfusion and apheresis science, 54(1), 2-15
Open this publication in new window or tab >>Adverse events in apheresis: an update of the WAA registry data
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2016 (English)In: Transfusion and apheresis science, ISSN 1473-0502, E-ISSN 1878-1683, Vol. 54, no 1, p. 2-15Article, review/survey (Refereed) Published
Abstract [en]

Apheresis with different procedures and devices are used for a variety of indications that may have different adverse events (AEs). The aim of this study was to clarify the extent and possible reasons of various side effects based on data from a multinational registry. The WAA-apheresis registry data focus on adverse events in a total of 50846 procedures in 7142 patients (42% women). AEs were graded as mild, moderate (need for medication), severe (interruption due to the AE) or death (due to AE). More AEs occurred during the first procedures versus subsequent (8.4 and 5.5%, respectively). AEs were mild in 2.4% (due to access 54%, device 7%, hypotension 15%, tingling 8%), moderate in 3% (tingling 58%, urticaria 15%, hypotension 10%, nausea 3%), and severe in 0.4% of procedures (syncope/hypotension 32%, urticaria 17%, chills/fever 8%, arrhythmia/asystole 4.5%, nausea/vomiting 4%). Hypotension was most common if albumin was used as the replacement fluid, and urticaria when plasma was used. Arrhythmia occurred to similar extents when using plasma or albumin as replacement. In 64% of procedures with bronchospasm, plasma was part of the replacement fluid used. Severe AEs are rare. Although most reactions are mild and moderate, several side effects may be critical for the patient. We present side effects in relation to the procedures and suggest that safety is increased by regular vital sign measurements, cardiac monitoring and by having emergency equipment nearby.

Place, publisher, year, edition, pages
Elsevier, 2016
Keywords
Apheresis, Adverse events, Plasma, Albumin, Donor
National Category
Urology and Nephrology Hematology
Identifiers
urn:nbn:se:umu:diva-120207 (URN)10.1016/j.transci.2016.01.003 (DOI)000374614700002 ()26776481 (PubMedID)
Available from: 2016-05-11 Created: 2016-05-11 Last updated: 2018-06-07Bibliographically approved
Söderholm, A., Öhman, A., Stenberg, B. & Nordin, S. (2016). Experience of living with nonspecific building-related symptoms. Scandinavian Journal of Psychology, 57(5), 406-412
Open this publication in new window or tab >>Experience of living with nonspecific building-related symptoms
2016 (English)In: Scandinavian Journal of Psychology, ISSN 0036-5564, E-ISSN 1467-9450, Vol. 57, no 5, p. 406-412Article in journal (Refereed) Published
Abstract [en]

Nonspecific building-related symptoms (NBRS) is a combination of general, skin and mucosal symptoms related to certain buildings. Despite high prevalence in the general population and severe symptomatology in certain cases there is no scientific documentation of quality of life in NBRS. The purpose of this study was to illuminate how individuals with NBRS experience daily life. Data were collected through descriptive, written texts and through telephone interviews with 11 individuals diagnosed with NBRS, and qualitative content analysis was conducted. Three main content areas were identified: (1) attitudes from the surrounding (categories: being questioned and lack of understanding from others; from zero to full support); (2) consequences (difficulties with daily activities; financial difficulties; affecting family and friends; emotional consequences); and (3) coping (learning to accept and finding solutions; avoiding; struggling; finding the positive; making one's home a sanctuary). As a conclusion, NBRS may affect several aspects of daily life, resulting in considerable alterations, limitations and emotional impact for the afflicted person and his/her family. Both environmental factors and attitudes from the surrounding can contribute to this impact on daily life. Strategies needed to cope with this impact may include both problem-focused and emotion-focused strategies, such as struggling, avoiding trigger factors and finding positive aspects.

Place, publisher, year, edition, pages
Wiley-Blackwell, 2016
Keywords
Attitudes, consequences, content analysis, coping, daily life, sick building syndrome
National Category
Public Health, Global Health, Social Medicine and Epidemiology Psychology
Identifiers
urn:nbn:se:umu:diva-127461 (URN)10.1111/sjop.12319 (DOI)000383707800004 ()27532686 (PubMedID)
Available from: 2016-11-14 Created: 2016-11-14 Last updated: 2018-06-09Bibliographically approved
Fall, S., Bruze, M., Isaksson, M., Liden, C., Matura, M., Stenberg, B. & Lindberg, M. (2015). Contact allergy trends in Sweden - a retrospective comparison of patch test data from 1992, 2000, and 2009. Contact Dermatitis, 72(5), 297-304
Open this publication in new window or tab >>Contact allergy trends in Sweden - a retrospective comparison of patch test data from 1992, 2000, and 2009
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2015 (English)In: Contact Dermatitis, ISSN 0105-1873, E-ISSN 1600-0536, Vol. 72, no 5, p. 297-304Article in journal (Refereed) Published
Abstract [en]

Background. Contact allergy prevalence rates change over time as a result of variations in allergen exposure. Data from patch test clinics are often used as markers for allergy trends.

Objectives. The aim of the present retrospective study was to describe trends in rates of sensitization to allergens in the Swedish baseline series. Patients/materials/methods. Prevalence rates are described by comparing consecutive patch test data from 1992, 2000 and 2009 in Swedish patch test clinics. In total, 3680 patients were included in 1992, 3825 in 2000, and 3112 in 2009.

Results. Among test substances with a sensitization rate above 2% in 2009, significant decreases were noted for nickel sulfate, cobalt chloride, colophonium, and methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI), and a significant increase for p-phenylenediamine, as compared with 1992. Potassium dichromate reactions had increased among younger women, whereas reactions to nickel and cobalt had decreased in this group. Sensitization to chromium, cobalt and fragrance mix I had decreased among older men, and sensitization to nickel had decreased among younger men.

Conclusions. It is probable that these changes in 1992-2009 reflect both changes in regulations for nickel, lower levels of chromium in cement and of MCI/MI in cosmetics, and increasing use of hair dyes.

Keywords
contact allergy, contact dermatitis, epidemiology, patch testing, prevalence, trends
National Category
Dermatology and Venereal Diseases
Identifiers
urn:nbn:se:umu:diva-103723 (URN)10.1111/cod.12346 (DOI)000353043300004 ()25600880 (PubMedID)
Available from: 2015-06-09 Created: 2015-05-28 Last updated: 2018-06-07Bibliographically approved
Glas, B., Stenberg, B., Stenlund, H. & Sunesson, A.-L. (2015). Exposure to formaldehyde, nitrogen dioxide, ozone, and terpenes among office workers and associations with reported symptoms. International Archives of Occupational and Environmental Health, 88(5), 613-622
Open this publication in new window or tab >>Exposure to formaldehyde, nitrogen dioxide, ozone, and terpenes among office workers and associations with reported symptoms
2015 (English)In: International Archives of Occupational and Environmental Health, ISSN 0340-0131, E-ISSN 1432-1246, Vol. 88, no 5, p. 613-622Article in journal (Refereed) Published
Abstract [en]

To compare exposure to formaldehyde, nitrogen dioxide, ozone and terpenes among office workers with and without sick building syndrome and the odds ratio for exposure. Are there significant differences? In this cross-sectional study of office workers, we investigated the associations between exposure to formaldehyde, nitrogen dioxide, ozone, alpha-pinene, and d-limonene using a case-control analysis. Data on perceived general, mucosal, and skin symptoms were obtained by questionnaires. Personal exposure measurements of the compounds were performed among cases and controls, and the odds ratios for exposures to the substances, both singly and in combination, were investigated. Exposures varied for formaldehyde between 0.23 and 45 A mu g/m(3), nitrogen dioxide between 0.26 and 110 A mu g/m(3), ozone between < 16 and 165 A mu g/m(3), alpha-pinene between 0.2 and 170 A mu g/m(3), and d-limonene between 0.8 and 1,400 A mu g/m(3). No consistent differences in exposure odds ratios were found between cases and controls or for individual symptoms.

Place, publisher, year, edition, pages
Berlin/Heidelberg: Springer Berlin/Heidelberg, 2015
Keywords
Formaldehyde, Nitrogen dioxide, Ozone, Terpenes, Office, Building-related symptoms
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:umu:diva-104754 (URN)10.1007/s00420-014-0985-y (DOI)000354624400009 ()25274505 (PubMedID)
Available from: 2015-06-15 Created: 2015-06-12 Last updated: 2018-06-07Bibliographically approved
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