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Lif Holgerson, PernillaORCID iD iconorcid.org/0000-0002-2779-5865
Alternative names
Publications (10 of 46) Show all publications
Anticona Huaynate, C., Lif Holgerson, P. & Gustafsson, P. E. (2023). Assessing inequities in unmet oral care needs among adults in Sweden: An intersectional approach. Community Dentistry and Oral Epidemiology, 51(3), 428-435
Open this publication in new window or tab >>Assessing inequities in unmet oral care needs among adults in Sweden: An intersectional approach
2023 (English)In: Community Dentistry and Oral Epidemiology, ISSN 0301-5661, E-ISSN 1600-0528, Vol. 51, no 3, p. 428-435Article in journal (Refereed) Published
Abstract [en]

Objectives: The goal of the Swedish oral healthcare system is to achieve good oral health and equitable access to care for the entire population. However, considerable inequities in oral health and care are evident and occur across a range of social dimensions. This study uses an intersectional approach to examine complex inequities in unmet oral care needs among adults in Sweden over the period 2004–2021.

Methods: Data were obtained from 14 Health on Equal Terms surveys conducted during 2004–2021. The final sample was 129 473 individuals aged 26–84 years. Applying intersectional analysis of individual heterogeneity and discriminatory accuracy, inequities in unmet oral care needs were estimated across 48 intersectional strata defined by gender, age, educational level, individual disposable income and immigrant status.

Results: A high risk of unmet oral care needs was found among strata consisting of immigrants and those with low income. However, being an immigrant and/or having a low income did not universally entail a high risk but varied by the social position along other axes, particularly age and education. The discriminatory accuracy was moderate.

Conclusion: Groups with certain social disadvantages are highly heterogeneous themselves. An intersectionality approach is important to prevent the risk of stigmatizing large heterogenous groups while failing to identify the most vulnerable strata. The discriminatory accuracy analysis suggested that further policy and/or interventions may be the most effective if approaching the whole population, combined with selected targeted interventions directed at the most disadvantaged social strata.

Place, publisher, year, edition, pages
John Wiley & Sons, 2023
Keywords
discriminatory accuracy, intersectionality, oral health care, social inequities, Sweden, unmet oral care needs
National Category
Public Health, Global Health, Social Medicine and Epidemiology Dentistry
Identifiers
urn:nbn:se:umu:diva-202347 (URN)10.1111/cdoe.12836 (DOI)000905784200001 ()36583509 (PubMedID)2-s2.0-85145277218 (Scopus ID)
Funder
Umeå University, FS 2.1.6-339-20
Available from: 2023-01-10 Created: 2023-01-10 Last updated: 2024-01-19Bibliographically approved
Lif Holgerson, P., Hasslöf, P., Esberg, A., Haworth, S., Domellöf, M., West, C. E. & Johansson, I. (2023). Genetic preference for sweet taste in mothers associates with mother-child preference and intake. Nutrients, 15(11), Article ID 2565.
Open this publication in new window or tab >>Genetic preference for sweet taste in mothers associates with mother-child preference and intake
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2023 (English)In: Nutrients, E-ISSN 2072-6643, Vol. 15, no 11, article id 2565Article in journal (Refereed) Published
Abstract [en]

Taste perception is a well-documented driving force in food selection, with variations in, e.g., taste receptor encoding and glucose transporter genes conferring differences in taste sensitivity and food intake. We explored the impact of maternal innate driving forces on sweet taste preference and intake and assessed whether their children differed in their intake of sweet foods or traits related to sweet intake. A total of 133 single nucleotide polymorphisms (SNPs) in genes reported to associate with eating preferences were sequenced from saliva-DNA from 187 mother-and-child pairs. Preference and intake of sweet-, bitter-, sour-, and umami-tasting foods were estimated from questionnaires. A total of 32 SNP variants associated with a preference for sweet taste or intake at a p-value < 0.05 in additive, dominant major, or dominant minor allele models, with two passing corrections for multiple testing (q < 0.05). These were rs7513755 in the TAS1R2 gene and rs34162196 in the OR10G3 gene. Having the T allele of rs34162196 was associated with higher sweet intake in mothers and their children, along with a higher BMI in mothers. Having the G allele of rs7513755 was associated with a higher preference for sweets in the mothers. The rs34162196 might be a candidate for a genetic score for sweet intake to complement self-reported intakes.

Place, publisher, year, edition, pages
MDPI, 2023
Keywords
NorthPop cohort, mothers with child, single nucleotide polymorphisms, sweet intake, sweet preference, taste
National Category
Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:umu:diva-209775 (URN)10.3390/nu15112565 (DOI)001004952500001 ()37299528 (PubMedID)2-s2.0-85161404366 (Scopus ID)
Funder
Region Västerbotten
Available from: 2023-06-13 Created: 2023-06-13 Last updated: 2023-08-28Bibliographically approved
Gormley, A., Haworth, S., Simancas-Pallares, M., Lif Holgerson, P., Esberg, A., Shrestha, P., . . . Johansson, I. (2023). Subtypes of early childhood caries predict future caries experience. Community Dentistry and Oral Epidemiology, 51(5), 966-975
Open this publication in new window or tab >>Subtypes of early childhood caries predict future caries experience
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2023 (English)In: Community Dentistry and Oral Epidemiology, ISSN 0301-5661, E-ISSN 1600-0528, Vol. 51, no 5, p. 966-975Article in journal (Refereed) Published
Abstract [en]

Objectives: To test whether postulated subtypes of early childhood caries (ECC) are predictive of subsequent caries experience in a population-based cohort of Swedish children.

Methods: The study included children aged between 3 and 5 years at study entry with dental records available for at least 5 years of follow-up. Dental record data were retrieved from the Swedish Quality Registry for Caries and Periodontal disease (SKaPa) for the initial and follow-up visits. Participants who had ECC at study entry were assigned to one of five ECC subtypes (termed classes 1-5) using latent class modelling of tooth surface-level caries experience. Subsequent experience of caries was assessed using the decayed, missing and filled surfaces indices (dmfs/DMFS) at follow-up visits, and compared between ECC subtypes using logistic and negative binomial regression modelling.

Results: The study included 128 355 children who had 3 or more dental visits spanning at least 5 years post-baseline. Of these children, 31 919 had caries at the initial visit. Baseline ECC subtype was associated with differences in subsequent disease experience. As an example, 83% of children who had a severe form of ECC at age 5 went on to have caries in the permanent dentition by the end of the study, compared to 51% of children who were caries-free at age 5 (adjusted odds ratio of 4.9 for new disease at their third follow-up).

Conclusion: ECC subtypes assigned at a baseline visit are associated with differences in subsequent caries experience in both primary and permanent teeth. This suggests that the development and future validation of an ECC classification can be used in addition to current prediction tools to help identify children at high risk of developing new caries lesions throughout childhood and adolescence.

Place, publisher, year, edition, pages
John Wiley & Sons, 2023
Keywords
ECC, caries prediction, children, latent class analysis
National Category
Dentistry Public Health, Global Health, Social Medicine and Epidemiology
Identifiers
urn:nbn:se:umu:diva-200323 (URN)10.1111/cdoe.12795 (DOI)000867567400001 ()36239051 (PubMedID)2-s2.0-85139796688 (Scopus ID)
Funder
Region Västerbotten
Available from: 2022-10-14 Created: 2022-10-14 Last updated: 2024-01-08Bibliographically approved
Kelk, P., Fasth, A., Lif Holgerson, P. & Sjöström, M. (2023). Successful complete oral rehabilitation of a patient with osteopetrosis with extensive pre-treatments, bone grafts, dental implants and fixed bridges: a multidisciplinary case report. BMC Oral Health, 23(1), Article ID 940.
Open this publication in new window or tab >>Successful complete oral rehabilitation of a patient with osteopetrosis with extensive pre-treatments, bone grafts, dental implants and fixed bridges: a multidisciplinary case report
2023 (English)In: BMC Oral Health, ISSN 1472-6831, E-ISSN 1472-6831, Vol. 23, no 1, article id 940Article in journal (Refereed) Published
Abstract [en]

Background: Osteopetrosis comprises a group of inherited disorders that are rare and result in abnormal bone structure. Bone remodeling is extremely inhibited because osteoclasts are nonfunctional or lacking. This condition causes overgrowth of bone with disappearance of the bone marrow, leading to aplastic anemia; obstruction of nerve passages in the skull leads to blindness and often hearing impairment. In most cases, osteopetrosis results in oral complications such as tooth deformation, hypomineralization, and delayed or absent tooth eruption. The only curative treatment is hematopoietic stem cell transplantation (HSCT). The main treatment of the oral complications during childhood and adolescence consists in protecting the erupted teeth against caries disease through prophylactic treatment aimed at optimal oral hygiene through frequent regular dental visits throughout life. Many patients with osteopetrosis require major oral rehabilitation to treat complications of the disease. Improved results of HSCT increase the likelihood that dental professionals will encounter patients with osteopetrosis.

Case presentation: In this case report, we show that individuals with osteopetrosis who have severe oral complications can be treated successfully if they are treated for osteopetrosis at an early age. The boy had his dental care in pedodontics, and regular multidisciplinary meetings were held for future treatment planning. At the age of 15, he was then referred for rehabilitation. The initial evaluations revealed no further growth in the alveolar bone. The rehabilitation was done stepwise, with extraction of malformed and malpositioned teeth. Initially, the patient received a removable partial denture followed by reconstruction of the width of the alveolar process, titanium implants, temporary fixed bridges, and finally screw-retained titanium-ceramic bridges with titanium frames for the upper and lower jaws.

Conclusions: The three-year follow-up after loading indicated a stable marginal bone level and optimal oral hygiene as a result of frequent professional oral hygiene care. The patient showed no signs of symptoms from the temporomandibular joint and has adapted to the new jaw relation without any functional or phonetical issues.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2023
Keywords
Hematopoietic stem cell transplantation, Iliac crest bone graft, Oral rehabilitation, Osseo integrated implants, Osteopetrosis
National Category
Dentistry
Identifiers
urn:nbn:se:umu:diva-217322 (URN)10.1186/s12903-023-03707-3 (DOI)38017429 (PubMedID)2-s2.0-85178240217 (Scopus ID)
Available from: 2023-11-30 Created: 2023-11-30 Last updated: 2023-12-14Bibliographically approved
Lif Holgerson, P., Esberg, A., West, C. E. & Johansson, I. (2023). The breast milk and childhood gastrointestinal microbiotas and disease outcomes: a longitudinal study. Pediatric Research, 93, 570-578
Open this publication in new window or tab >>The breast milk and childhood gastrointestinal microbiotas and disease outcomes: a longitudinal study
2023 (English)In: Pediatric Research, ISSN 0031-3998, E-ISSN 1530-0447, Vol. 93, p. 570-578Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: We aimed to characterize breast milk microbiota and define associations with saliva and fecal microbiota and selected diseases in preschool children.

METHODS: In a longitudinal cohort study, the microbiotas from breast milk, mouth, and fecal samples were characterized by 16S rRNA gene sequencing. Questionnaires and medical records provided information on demographics, medical, and dental data.

RESULTS: The phylogeny in breast milk, saliva swabs, and feces differed at all levels (p < 0.0003), though all harbored species in Streptococcus, Veillonella, and Haemophilus. Species richness was highest in breast milk with increasing resemblance with the oral swab microbiota by increasing age. Caries-affected children at age 5 had been fed breast milk with tenfold higher abundance of caries-associated bacteria, e.g., Streptococcus mutans, than caries-free children (p < 0.002). At that age, taxa, e.g., Neisseria sicca were overrepresented in saliva swabs of children with otitis media (LDA score >2, p < 0.05). Gut symbionts, e.g., Bacteroides, were underrepresented in 3-month fecal samples in children later diagnosed with allergic disease (LDA score >2, p < 0.05).

CONCLUSIONS: Distinct microbiotas for the three sources were confirmed, though resemblance between milk and oral swab microbiota increased by age. Future studies should evaluate if the observed associations with disease outcomes are causal.

IMPACT: Few studies have studied the association between breast milk microbiota and gastrointestinal microbiota beyond early infancy. The present study confirms distinct microbiota profiles in breast milk, saliva swabs, and feces in infancy and indicates increasing resemblance between breast milk and the oral microbiota by increasing age. The fecal microbiota at 3 months was associated with later allergic disease; the saliva microbiota by age 5 differed between children with and without otitis media at the same age; and children with caries by age 5 had been fed breast milk with a higher abundance of caries-associated bacteria.

Place, publisher, year, edition, pages
Springer Nature, 2023
National Category
Dentistry Pediatrics
Research subject
Odontology; Microbiology
Identifiers
urn:nbn:se:umu:diva-200175 (URN)10.1038/s41390-022-02328-w (DOI)000865693900002 ()36216869 (PubMedID)2-s2.0-85139603963 (Scopus ID)
Funder
Region Västerbotten, 146701Region Västerbotten, 463701Region Västerbotten, 550361Region Västerbotten, 581231
Available from: 2022-10-11 Created: 2022-10-11 Last updated: 2023-07-14Bibliographically approved
Haworth, S., Kho, P. F., Lif Holgerson, P., Hwang, L.-D., Timpson, N. J., Renteria, M. E., . . . Cuellar-Partida, G. (2021). Assessment and visualization of phenome-wide causal relationships using genetic data: an application to dental caries and periodontitis. European Journal of Human Genetics, 29, 300-308
Open this publication in new window or tab >>Assessment and visualization of phenome-wide causal relationships using genetic data: an application to dental caries and periodontitis
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2021 (English)In: European Journal of Human Genetics, ISSN 1018-4813, E-ISSN 1476-5438, Vol. 29, p. 300-308Article in journal (Refereed) Published
Abstract [en]

Hypothesis-free Mendelian randomization studies provide a way to assess the causal relevance of a trait across the human phenome but can be limited by statistical power, sample overlap or complicated by horizontal pleiotropy. The recently described latent causal variable (LCV) approach provides an alternative method for causal inference which might be useful in hypothesis-free experiments across human phenome. We developed an automated pipeline for phenome-wide tests using the LCV approach including steps to estimate partial genetic causality, filter to a meaningful set of estimates, apply correction for multiple testing and then present the findings in a graphical summary termed causal architecture plot. We apply this pipeline to body mass index (BMI) and lipid traits as exemplars of traits where there is strong prior expectation for causal effects, and to dental caries and periodontitis as exemplars of traits where there is a need for causal inference. The results for lipids and BMI suggest that these traits are best viewed as contributing factors on a multitude of traits and conditions, thus providing additional evidence that supports viewing these traits as targets for interventions to improve health. On the other hand, caries and periodontitis are best viewed as a downstream consequence of other traits and diseases rather than a cause of ill health. The automated pipeline is implemented in the Complex-Traits Genetics Virtual Lab (https:// vl.genoma.io) and results are available in. We propose causal architecture plots based on phenome-wide partial genetic causality estimates as a new way visualizing the overall causal map of the human phenome.

Place, publisher, year, edition, pages
Springer Nature, 2021
National Category
Dentistry Medical Genetics
Identifiers
urn:nbn:se:umu:diva-176082 (URN)10.1038/s41431-020-00734-4 (DOI)000574800000001 ()33011735 (PubMedID)2-s2.0-85091881730 (Scopus ID)
Available from: 2020-10-21 Created: 2020-10-21 Last updated: 2023-03-24Bibliographically approved
Dodhia, S. A., West, N. X., Thomas, S. J., Timpson, N. J., Johansson, I., Lif Holgerson, P., . . . Haworth, S. (2021). Examining the causal association between 25-hydroxyvitamin D and caries in children and adults: A two-sample Mendelian randomization approach. Wellcome Open Research, 5, Article ID 281.
Open this publication in new window or tab >>Examining the causal association between 25-hydroxyvitamin D and caries in children and adults: A two-sample Mendelian randomization approach
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2021 (English)In: Wellcome Open Research, E-ISSN 2398-502X, Vol. 5, article id 281Article in journal (Refereed) Published
Abstract [en]

Background: Prior observational studies have reported that higher levels of vitamin D are associated with decreased caries risk in children. However, these studies are prone to bias and confounding so do not provide causal inference. Genetic variants associated with a risk factor of interest can be used as proxies, in a Mendelian randomization (MR) analysis, to test for causal association with an outcome. The objective was to estimate the causal association between serum 25-hydroxyvitamin D (25(OH)D) (the commonly measured vitamin D metabolite in blood) and dental caries using a two-sample MR approach which estimates the causal effect of an exposure on an outcome.

Methods: A total of 79 genetic variants reliably associated with 25(OH)D were identified from genome-wide association studies and used as a proxy measure of 25(OH)D. The association of this proxy measure with three outcome measures was tested; specifically: caries in primary teeth (n=17,035, aged 3-12 years), caries in permanent teeth in childhood and adolescence (n=13,386, aged 6-18 years), and caries severity in adulthood proxied by decayed, missing and filled tooth surfaces (DMFS) counts (n=26,792, aged 18-93 years).

Results: The estimated causal effect of a one standard deviation increase in natural log-transformed 25(OH)D could be summarized as an odds ratio of 1.06 (95%CI: 0.81, 1.31; P=0.66) for caries in primary teeth and 1.00 (95%CI: 0.76, 1.23; P=0.97) for caries in permanent teeth in childhood and adolescence. In adults, the estimated casual effect of a one standard deviation increase in natural log-transformed 25(OH)D was 0.31 fewer affected tooth surfaces (95%CI: from 1.81 fewer DMFS to 1.19 more DMFS; P=0.68)

Conclusions: The MR-derived effect estimates for these three measures are small in magnitude with wide confidence intervals and do not provide evidence for a causal relationship between 25(OH)D and dental caries.

Place, publisher, year, edition, pages
F1000 Research Ltd, 2021
Keywords
25-hydroxyvitamin D, Dental caries, Mendelian randomization, Vitamin D
National Category
Dentistry
Identifiers
urn:nbn:se:umu:diva-186645 (URN)10.12688/wellcomeopenres.16369.2 (DOI)34386609 (PubMedID)2-s2.0-85111960661 (Scopus ID)
Note

Version 1 of this article: Dodhia SA, West NX, Thomas SJ et al. "Is vitamin D a modifiable risk factor for dental caries? [version 1; peer review: 1 approved, 1 approved with reservations]". Wellcome Open Res 2020, 5:281, DOI: 10.12688/wellcomeopenres.16369.1

Available from: 2021-08-19 Created: 2021-08-19 Last updated: 2021-11-10Bibliographically approved
Esberg, A., Eriksson, L., Hasslöf, P., Haworth, S., Lif Holgerson, P. & Johansson, I. (2021). Using Oral Microbiota Data to Design a Short Sucrose Intake Index. Nutrients, 13(5), Article ID 1400.
Open this publication in new window or tab >>Using Oral Microbiota Data to Design a Short Sucrose Intake Index
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2021 (English)In: Nutrients, E-ISSN 2072-6643, Vol. 13, no 5, article id 1400Article in journal (Refereed) Published
Abstract [en]

Excessive sucrose consumption is associated with numerous health problems, including dental caries, and is considered to play a critical role in shaping the human microbiota. Here, we aimed to confirm the association between sucrose exposure and oral microbiota profile, develop a short food-based index capturing variation among sucrose consumers and validate it against oral microbiota and dental caries in a derivation cohort with 16- to 79-year-old participants (n = 427). Intake and food preferences were recorded by questionnaires and saliva microbiota by 16S rDNA sequencing. Taxonomic similarities clustered participants into five clusters, where one stood out with highest sucrose intake and predicted sugar related metabolic pathways but lowest species diversity in the microbiota. Multivariate modelling of food intake and preferences revealed foods suitable for a sucrose index. This, similarly to sucrose intake, was related to bacterial pattern and caries status. The validity of the sucrose index was replicated in the population-based Gene-Lifestyle Interactions in Dental Endpoints (GLIDE, n = 105,520 Swedish adults) cohort. This suggested that the index captured clinically relevant variation in sucrose intake and that FFQ derived information may be suitable for screening of sucrose intake in the clinic and epidemiological studies, although adjustments to local consumption habits are needed.

Keywords
caries, saliva microbiota, sucrose, sucrose index
National Category
Clinical Medicine
Identifiers
urn:nbn:se:umu:diva-182675 (URN)10.3390/nu13051400 (DOI)000662387600001 ()33919427 (PubMedID)2-s2.0-85104437409 (Scopus ID)
Funder
Swedish Research Council, 2011-03372Swedish Research Council, 2015-02597Region Västerbotten
Available from: 2021-05-01 Created: 2021-05-01 Last updated: 2023-09-05Bibliographically approved
Lif Holgerson, P., Esberg, A., Sjödin, A., West, C. E. & Johansson, I. (2020). A longitudinal study of the development of the saliva microbiome in infants 2 days to 5 years compared to the microbiome in adolescents. Scientific Reports, 10(1), Article ID 9629.
Open this publication in new window or tab >>A longitudinal study of the development of the saliva microbiome in infants 2 days to 5 years compared to the microbiome in adolescents
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2020 (English)In: Scientific Reports, E-ISSN 2045-2322, Vol. 10, no 1, article id 9629Article in journal (Refereed) Published
Abstract [en]

Understanding oral microbiota programming attracts increasing interest due to its importance for oral health and potential associations with systemic diseases. Here the oral microbiota was longitudinally characterized in children from 2 days (n = 206) to 5 years of age and in young adults (n = 175) by sequencing of the v3-v4 region of the 16S rRNA gene from saliva extracted DNA. Alpha diversity increased by age, with 2-day- and 3-month-old infants in one sub-group, and 18-month- and 3-year-old children in another. Firmicutes decreased up to 3 years of age, whereas Proteobacteria, Actinobacteria, Bacteroidetes and Fusobacteria abundances increased. Abiotrophia, Actinomyces, Capnocytophaga, Corynebacterium, Fusobacterium, Kingella, Leptotrichia, Neisseria and Porphyromonas appeared from 18-months of age. This was paralleled by expansions in the core microbiome that continued up to adulthood. The age-related microbiota transformation was paralleled by functional alterations, e.g., changed metabolic pathways that reflected e.g., breastfeeding and increasing proportions of anaerobic species. Oral microbiotas differed by feeding mode and weakly by mode of delivery, but not gender, pacifier use or cleaning method or probiotic intake. The study shows that the saliva microbiota is diverse 2 days after birth and under transformation up to 5 years of age and beyond, with fluctuations possibly reflecting age-related environmental influences.

Place, publisher, year, edition, pages
Nature Publishing Group, 2020
National Category
Other Health Sciences
Research subject
Odontology
Identifiers
urn:nbn:se:umu:diva-172335 (URN)10.1038/s41598-020-66658-7 (DOI)000544936100031 ()32541791 (PubMedID)2-s2.0-85086623819 (Scopus ID)
Funder
Västerbotten County Council
Available from: 2020-06-18 Created: 2020-06-18 Last updated: 2023-03-24Bibliographically approved
Esberg, A., Barone, A., Eriksson, L., Lif Holgerson, P., Teneberg, S. & Johansson, I. (2020). Corynebacterium matruchotii Demography and Adhesion Determinants in the Oral Cavity of Healthy Individuals. Microorganisms, 8(11), Article ID 1780.
Open this publication in new window or tab >>Corynebacterium matruchotii Demography and Adhesion Determinants in the Oral Cavity of Healthy Individuals
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2020 (English)In: Microorganisms, E-ISSN 2076-2607, Vol. 8, no 11, article id 1780Article in journal (Refereed) Published
Abstract [en]

Corynebacterium matruchotii may be key in tooth biofilm formation, but information about demographics, bacterial partners, and binding ligands is limited. The aims of this study were to explore C. matruchotii's demography by age and colonization site (plaque and saliva), in vitro bacterial-bacterial interactions in coaggregation and coadhesion assays, and glycolipids as potential binding ligands in thin-layer chromatogram binding assays. C. matruchotii prevalence increased from 3 months to 18 years old, with 90% and 100% prevalence in saliva and tooth biofilm, respectively. C. matruchotii aggregated in saliva in a dose-dependent manner but lacked the ability to bind to saliva-coated hydroxyapatite. In vivo, C. matruchotii abundance paralleled that of Actinomyces naeslundii, Capnocytophaga sp. HMT 326, Fusobacterium nucleatum subsp. polymorphum, and Tannerella sp. HMT 286. In vitro, C. matruchotii bound both planktonic and surface-bound A. naeslundii, Actinomyces odontolyticus, and F. nucleatum. In addition, C. matruchotii exhibited the ability to bind glycolipids isolated from human erythrocytes (blood group O), human granulocytes, rabbit intestine, human meconium, and rat intestine. Binding assays identified candidate carbohydrate ligands as isoglobotriaosylceramide, Gal alpha 3-isoglobotriaosylceramide, lactotriaosylceramide, lactotetraosylceramide, neolactotetraosylceramide, and neolactohexaosylceramide. Thus, C. matruchotii likely uses specific plaque bacteria to adhere to the biofilm and may interact with human tissues through carbohydrate interactions.

Place, publisher, year, edition, pages
MDPI, 2020
Keywords
Corynebacterium matruchotii, demographics, aggregation, ligand, glycolipids
National Category
Dentistry
Identifiers
urn:nbn:se:umu:diva-177783 (URN)10.3390/microorganisms8111780 (DOI)000593212300001 ()33202844 (PubMedID)2-s2.0-85096612754 (Scopus ID)
Funder
Swedish Cancer Society, 18 0760
Available from: 2020-12-18 Created: 2020-12-18 Last updated: 2023-03-24Bibliographically approved
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0002-2779-5865

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