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Edman, Anne-Christine
Publications (2 of 2) Show all publications
Carré, H., Edman, A.-C., Boman, J. & Nylander, E. (2008). Chlamydia trachomatis in the throat: is testing necessary?. Acta Dermato-Venereologica, 88(2), 187-188
Open this publication in new window or tab >>Chlamydia trachomatis in the throat: is testing necessary?
2008 (English)In: Acta Dermato-Venereologica, ISSN 0001-5555, E-ISSN 1651-2057, ISSN ISSN 0001-5555, EISSN 1651-2057, Vol. 88, no 2, p. 187-188Article in journal (Refereed) Published
Identifiers
urn:nbn:se:umu:diva-23588 (URN)10.2340/00015555-0382 (DOI)18311460 (PubMedID)
Available from: 2009-06-26 Created: 2009-06-26 Last updated: 2018-06-08Bibliographically approved
Edman, A.-C. (1988). Myofibrillens finstruktur i tvärstrimmig skelettmuskulatur. (Doctoral dissertation). Umeå: Umeå universitet
Open this publication in new window or tab >>Myofibrillens finstruktur i tvärstrimmig skelettmuskulatur
1988 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

The detailed structure of the myofibrillar material in fibres from different muscles has been studied. Specimens have been obtained from human muscles and from different muscles frequently examined in experimental studies. Both light- and electron microscopical techniques have been used. Of central importance has been the method, which makes it possible to prepare ultrathin sections of frozen tissue, i.e. cryo-ult- ramicrotomy. A number of techniques for image analysis have been applied in order to obtain objektive data from the micrographs.

In Paper I the present knowledge about muscle fibre structure, cryo-- sectioning and image analysis is summarized and relevant methodological problems are discussed. Paper II describes the detailed structure of the C-zone of the A-band and shows, above all, that structures occur with different repeats along the long axis of the myofibril. Paper III describes the subcellular organization of different fibres in a homogeneous (based on enzyme histochemical mATPase) population, and shows that different structural characteristies can vary independently of each other. Paper IV describes the structural diversity of the myofibrillar M-band, and paper V the diversity of the myofilament fine structure in different fibres. The results show that there is a most sophisticated, and previosly unrealized, structural specialization both within the myofibrils and between myofibrils from different fibres and muscles, even if the fibres are of the same fibre type. The findings suggest that generally used models, showing the structural organization within myofibrils and myofilaments, are oversimplifications. The fibre population is more heterogeneously built up than the common systems for fibre type classification makes one to belive.

Place, publisher, year, edition, pages
Umeå: Umeå universitet, 1988. p. 32
Series
Umeå University medical dissertations, ISSN 0346-6612 ; 217
Keywords
Muscle, muscle fibre, fibre type, myofilament, A-band, M-band, cryo-ultramicrotomy, electron microscopy, image analysis
National Category
Neurology
Identifiers
urn:nbn:se:umu:diva-99292 (URN)
Public defence
1988-05-18, Föreläsningsal B (9 tr), Tandläkarhögskolan Umeå universitet, Umeå universitet, Umeå, 09:00
Supervisors
Projects
digitalisering@umu
Note

Diss. (sammanfattning) Umeå : Umeå universitet, 1988, härtill 5 uppsatser.

Available from: 2015-02-06 Created: 2015-02-05 Last updated: 2018-06-07Bibliographically approved
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