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Doorn, Jan van
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Publications (10 of 38) Show all publications
Lohmander, A., McAllister, A., Hansson, K., Hartelius, L., Blom Johansson, M., Karlsson, F., . . . van Doorn, J. (2017). Kommunikations- och sväljstörningar genom hela livet: ett logopediskt ståndpunktsdokument. Umeå: Umeå universitet
Open this publication in new window or tab >>Kommunikations- och sväljstörningar genom hela livet: ett logopediskt ståndpunktsdokument
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2017 (Swedish)Report (Other academic)
Abstract [sv]

Den forskning som bedrivs inom logopedi i Sverige idag spänner över ett brett spektrum av medfödda, utvecklingsrelaterade och förvärvade kommunikationsstörningar på grund av röst-, tal- och språksvårigheter samt sväljstörningar. Precis som i andra länder pågår en snabb utveckling både mot en breddning av det urval av områden som det forskas kring och ett ökat fokus på nationellt samarbete. Även om de framsteg som görs inom respektive fält kan mätas genom de forskningsrapporter som publiceras av respektive forskargrupper, finns det ett behov av att granska vilka forskningsinsatser som bedrivs jämte det demografiska sammanhanget. I detta ståndpunktsdokument ger vi en översikt över logopediämnet och den forskning som bedrivs i Sverige. I en kubmodell illustreras hur kommunikations- och sväljstörningar kan beskrivas. Stratifierade (per åldersintervall) uppskattningar av prevalensen av kommunikations- och sväljstörningar ges baserat på 2016 års befolkningsstruktur. Genom att presentera dessa två komponenter identifieras forskningsområden och riktningar inom logopedi som behöver ges ökad uppmärksamhet i det kommande forskningsarbetet.

Place, publisher, year, edition, pages
Umeå: Umeå universitet, 2017. p. 11
Keywords
Logopedi, Forskningsöversikt
National Category
Other Medical Sciences not elsewhere specified
Identifiers
urn:nbn:se:umu:diva-139757 (URN)
Available from: 2017-09-26 Created: 2017-09-26 Last updated: 2018-06-09Bibliographically approved
Eklund, E., Qvist, J., Sandström, L., Viklund, F., Doorn, J. v. & Karlsson, F. (2015). Perceived articulatory precision in patients with Parkinson’s disease after deep brain stimulation of subthalamic nucleus and caudal zona incerta. Clinical Linguistics & Phonetics, 29(2), 150-166
Open this publication in new window or tab >>Perceived articulatory precision in patients with Parkinson’s disease after deep brain stimulation of subthalamic nucleus and caudal zona incerta
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2015 (English)In: Clinical Linguistics & Phonetics, ISSN 0269-9206, E-ISSN 1464-5076, Vol. 29, no 2, p. 150-166Article in journal (Refereed) Published
Abstract [en]

The effect of deep brain stimulation (DBS) of the subthalamic nucleus (STN) and caudal zona incerta (cZi) on speech articulation in patients with Parkinson’s disease (PD) was investigated. Read speech samples were collected from nine patients with STN-DBS and ten with cZi-DBS. The recordings were made preoperatively and 12 months postoperatively with stimulator on and off (on medication). Blinded, randomized, repeated perceptual assessments were performed on words and isolated fricatives extracted from the recordings to assess 1) overall articulatory quality ratings, 2) frequency of occurrence of misarticulation patterns, and 3) fricative production. Statistically significant worsening of articulatory measures on- compared with off-stimulation occurred in the cZi-DBS group, with deteriorated articulatory precision ratings, increased presence of misarticulations (predominately altered realizations of plosives and fricatives) and a reduced accuracy in fricative production. A similar, but not significant, trend was found for the STN-DBS group. 

Keywords
Assessment, deep brain stimulation, dysarthria, Parkinson’s disease, phonetics
National Category
Other Medical Sciences not elsewhere specified
Research subject
Linguistics; Neurosurgery
Identifiers
urn:nbn:se:umu:diva-93676 (URN)10.3109/02699206.2014.971192 (DOI)000348045700005 ()25333411 (PubMedID)
Projects
En kontrastiv och longitudinell studie gällande effekten av djup hjärnstimulering på Parkinsons-patienters artikulatoriska förmåga.
Funder
Swedish Research Council, 2009-946Swedish Research Council, 2011-2294
Available from: 2014-09-30 Created: 2014-09-30 Last updated: 2018-06-07Bibliographically approved
Karlsson, F., Olofsson, K., Blomstedt, P., Linder, J., Nordh, E. & van Doorn, J. (2014). Articulatory closure proficiency in Parkinson's disease patients following deep brain stimulation of the subthalamic nucleus and caudal zona incerta.. Journal of Speech, Language and Hearing Research, 57, 1178-1190
Open this publication in new window or tab >>Articulatory closure proficiency in Parkinson's disease patients following deep brain stimulation of the subthalamic nucleus and caudal zona incerta.
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2014 (English)In: Journal of Speech, Language and Hearing Research, ISSN 1092-4388, E-ISSN 1558-9102, Vol. 57, p. 1178-1190Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE

The present study aimed at comparing the effects of deep brain stimulation (DBS) treatment of the subthalamic nucleus (STN) and the caudal zona incerta (cZi) on Parkinson's disease patients' proficiency in achieving oral closure and release during plosive production. METHODS Nineteen patients were evaluated preoperatively and 12 months after DBS surgery. Nine patients were implanted in the STN, seven bilaterally and two unilaterally (left). Ten were bilaterally implanted in the cZi. Postoperative examinations were made off and on stimulation. All patients received simultaneous L-dopa treatment in all conditions. For a series of plosives extracted from a reading passage, absolute and relative measures of duration of frication and amplitude of plosive release were compared between conditions within each treatment group. RESULTS Relative duration of frication increased in voiceless plosives in the on stimulation condition in cZi patients. Similar trends were observed across the data set. Duration of pre-release frication and the release peak prominence increased in voiceless plosives on stimulation for both groups. CONCLUSIONS The increased release prominence suggests that patients achieved a stronger closure gesture due to DBS, but that the increased energy available resulted in increased frication.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:umu:diva-90957 (URN)10.1044/2014_JSLHR-S-13-0010 (DOI)000348198000004 ()24686561 (PubMedID)
Available from: 2014-07-04 Created: 2014-07-04 Last updated: 2018-06-07Bibliographically approved
Louise, J., Sofia, M., Olofsson, K., Linder, J., Nordh, E., Blomstedt, P., . . . Karlsson, F. (2014). Word-level intelligibility after caudal zona incerta stimulation for Parkinson’s disease. Acta Neurologica Scandinavica, 130(1), 27-33
Open this publication in new window or tab >>Word-level intelligibility after caudal zona incerta stimulation for Parkinson’s disease
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2014 (English)In: Acta Neurologica Scandinavica, ISSN 0001-6314, E-ISSN 1600-0404, Vol. 130, no 1, p. 27-33Article in journal (Refereed) Published
Abstract [en]

Objectives – To investigate the effect of caudal zona incerta-deep brain stimulation (cZi-DBS) on word-level speech intelligibility in patients with Parkinson’s disease, under both an optimal listening condition and a simulated more naturalistic listening condition.

Materials and methods – Spoken single words were extracted from read samples collected from 10 bilaterally implanted patients with PD pre- and post-cZi-DBS. Intelligibility was assessed through a transcription task performed by 32 naive listeners under two listening conditions: (i) with low-amplitude conversational speech added as background and (ii) with no added background noise. The listeners′ responses were scored in terms of agreement with the intended words.

Results – Post-operatively, the total intelligibility score was significantly lower when cZi stimulation was switched on compared with off, for both listening conditions (with and without added background noise). Intelligibility was also significantly lower on stimulation compared with preoperative recordings, but only when assessed in the listening condition without background noise. The listening condition with added background noise resulted in significantly lower intelligibility scores compared with the no added noise condition for all stimulation conditions.

Conclusions – The results of this study indicate that cZi-DBS in patients with PD can be detrimental to word-level speech intelligibility. 

Place, publisher, year, edition, pages
Wiley-Blackwell, 2014
Keywords
caudal zona incerta, deep brain stimulation, Parkinson's disease, speech intelligibility
National Category
Other Medical Sciences not elsewhere specified
Research subject
Neurology; Linguistics; Neurosurgery
Identifiers
urn:nbn:se:umu:diva-84232 (URN)10.1111/ane.12210 (DOI)000337633400004 ()
Projects
En kontrastiv och longitudinell studie gällande effekten av djup hjärnstimulering på Parkinsons-patienters artikulatoriska förmåga.Intonation and rhythm in speech of patients with Parkinson ́s disease
Funder
Swedish Research Council, 2009-946Swedish Research Council, 2011- 2294
Available from: 2013-12-19 Created: 2013-12-19 Last updated: 2018-06-08Bibliographically approved
Kulneff, L., Sundstedt, S., Olofsson, K., van Doorn, J., Linder, J., Nordh, E. & Blomstedt, P. (2013). Deep brain stimulation: effects on swallowing function in Parkinson's disease. Acta Neurologica Scandinavica, 127(5), 329-336
Open this publication in new window or tab >>Deep brain stimulation: effects on swallowing function in Parkinson's disease
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2013 (English)In: Acta Neurologica Scandinavica, ISSN 0001-6314, E-ISSN 1600-0404, Vol. 127, no 5, p. 329-336Article in journal (Refereed) Published
Abstract [en]

Objective: In patients with Parkinson’s disease (PD), deep brainstimulation of the subthalamic nucleus (STN DBS) is well recognizedin improving limb function, but the outcome on swallowing functionhas rarely been studied. The aim of this work was to evaluate theeffect of STN DBS on pharyngeal swallowing function in patientswith PD using self-estimation and fiberoptic endoscopic evaluation ofswallowing.

Methods: Eleven patients (aged 41–72, median 61 years)were evaluated preoperatively and at 6 and 12 months after STN DBSsurgery. All patients were evaluated with self-estimation on a visualanalogue scale, and eight of them with a fiberoptic endoscopicexamination with a predefined swallowing protocol includingRosenbek’s Penetration-Aspiration Scale, Secretion Severity Scale,preswallow spillage, pharyngeal residue, and pharyngeal clearance.

Results: The self-assessments of swallowing function revealed asubjective improvement with STN DBS stimulation, whereas the datafrom the swallowing protocol did not show any significant effect ofthe STN DBS treatment itself. The prevalence of aspiration was notaffected by the surgery.

Conclusions: The results show thatswallowing function was not negatively affected by STN DBS and therisk of aspiration did not increase. Self-estimation of swallowingfunction showed a subjective improvement due to stimulation.

Place, publisher, year, edition, pages
Hoboken: Wiley-Blackwell, 2013
Keywords
deep brain stimulation, subthalamic nucleus, dysphagia, Parkinson’s disease, fiberoptic endoscopic evaluation of swallowing, swallowing function, aspiration, L-dopa
National Category
Otorhinolaryngology
Research subject
Medicine
Identifiers
urn:nbn:se:umu:diva-61453 (URN)10.1111/ane.12019 (DOI)000317859900008 ()
Projects
Speech, voice and swallowing outcomes after deep brain stimulation (DBS)
Available from: 2013-04-11 Created: 2012-11-14 Last updated: 2018-06-08Bibliographically approved
van Doorn, J., Ahlinder, A. & Labba, J. (2013). Development of a speech assessment tool (SIV) for use by health professionals who work with DBS patients. Movement Disorders, 28(Suppl 1), S452-S453
Open this publication in new window or tab >>Development of a speech assessment tool (SIV) for use by health professionals who work with DBS patients
2013 (English)In: Movement Disorders, ISSN 0885-3185, E-ISSN 1531-8257, Vol. 28, no Suppl 1, p. S452-S453Article in journal, Meeting abstract (Refereed) Published
Place, publisher, year, edition, pages
John Wiley & Sons, 2013
National Category
Other Health Sciences
Identifiers
urn:nbn:se:umu:diva-74926 (URN)
Available from: 2013-07-02 Created: 2013-07-02 Last updated: 2018-06-08Bibliographically approved
van Doorn, J. & Karlsson, F. (2013). Influence of speech task and utterance length on measurement of pitch variability in the speech of Parkinson's disease patients after deep brain stimulation. Paper presented at Seventeenth International Congress of Parkinson's Disease and Movement Disorders, Sydney, Australia, June 16-20, 2013. Movement Disorders, 28(Supplement 1), S448
Open this publication in new window or tab >>Influence of speech task and utterance length on measurement of pitch variability in the speech of Parkinson's disease patients after deep brain stimulation
2013 (English)In: Movement Disorders, ISSN 0885-3185, E-ISSN 1531-8257, Vol. 28, no Supplement 1, p. S448-Article in journal, Meeting abstract (Refereed) Published
Place, publisher, year, edition, pages
John Wiley & Sons, 2013
National Category
Other Medical Sciences not elsewhere specified
Research subject
Linguistics; Neurology; Neurosurgery; Oto-Rhino-Laryngology
Identifiers
urn:nbn:se:umu:diva-74410 (URN)10.1002/mds.25605 (DOI)
Conference
Seventeenth International Congress of Parkinson's Disease and Movement Disorders, Sydney, Australia, June 16-20, 2013
Funder
Swedish Research Council, 2011-2294
Available from: 2013-06-27 Created: 2013-06-27 Last updated: 2018-06-08Bibliographically approved
Doorn, J. v. & Karlsson, F. (2013). Influence of speech task and utterance length on the measurement of pitch variability in the speech of Parkinson's disease patients after deep brain stimulation. In: : . Paper presented at 17th International Congress of Parkinson's disease and movement disorders.
Open this publication in new window or tab >>Influence of speech task and utterance length on the measurement of pitch variability in the speech of Parkinson's disease patients after deep brain stimulation
2013 (English)Conference paper, Poster (with or without abstract) (Other academic)
Abstract [en]

Parkinson’s disease (PD) affects patients voice characteristics, reducing pitch variability compared to normal controls (1,2). Previous reports have shown an increase in pitch variability due to deep brain stimulation (DBS) of the Subthalamic nucleus (STN) (3). For patients stimulated in caudal zona incerta (cZi), the results indicate no effect on pitch variability in a read speech task{Karlsson:2012jr}.

The present study aimed at investigating the effects of speech task (spontaneous or read speech) and the lenght of the utterance on overall measures of pitch variability observed in DBS-treated patients. Ten patients treated with STN-DBS and ten patients treated with cZi-DBS were included in this prospective study.

Utterances produced sponatenously and produced during readings of a standard passage were compared in terms of treatment effects in pitch variability due to STN-DBS and cZi-DBS (Stim OFF and Stim ON recordings made 1,5 hour apart, all in Med ON) 6 and 12 months after operation. The results indicate that pitch variability is affected differently by STN-DBS and cZi-DBS depending on speech task and utterance length. In short utterances (<10 words), an increase in pitch variability is observed for both treatment groups and both speech tasks. For longer utterances, however, a more diverse effect of treatment and speech task is observed. The results therefore suggest that spech task and characteristics of thate utterance should be carefully considered when drawing conclusions on the overall effect of DBS on pitch variability.

1. Jiménez-Jiménez FJ, Gamboa J, Nieto A, Guerrero J, Ortí-Pareja M, Molina JA, et al. Acoustic voice analysis in untreated patients with Parkinson's disease. Parkinsonism Relat. Disord. 1997 Apr;3(2):111–6. 

2. Holmes RJ, Oates JM, Phyland DJ, Hughes AJ. Voice characteristics in the progression of Parkinson’s disease. International Journal of Language & Communication Disorders. 2000;35(3):407–18. 

3. Dromey C, Kumar R, Lang AE, Lozano AM. An investigation of the effects of subthalamic nucleus stimulation on acoustic measures of voice. Mov. Disord. 2000;15(6):1132–8.

National Category
Other Medical Sciences not elsewhere specified Otorhinolaryngology
Research subject
Linguistics
Identifiers
urn:nbn:se:umu:diva-73374 (URN)
Conference
17th International Congress of Parkinson's disease and movement disorders
Projects
Intonation och rytm i talet hos personer med Parkinsons sjukdom - en longitudinell jämförelse mellan sjukdomens effekter och effekter av behandling
Funder
Swedish Research Council, 2011-2294
Available from: 2013-06-20 Created: 2013-06-20 Last updated: 2018-06-08Bibliographically approved
Jonsson, M., van Doorn, J. & van den Bergh, J. (2013). Parents’ perceptions of eating skills of pre-term vs full-term infants from birth to 3 years. International Journal of Speech-Language Pathology, 15(6), 604-612
Open this publication in new window or tab >>Parents’ perceptions of eating skills of pre-term vs full-term infants from birth to 3 years
2013 (English)In: International Journal of Speech-Language Pathology, ISSN 1754-9507, E-ISSN 1754-9515, Vol. 15, no 6, p. 604-612Article in journal (Refereed) Published
Abstract [en]

Difficulties with feeding and eating are more common among pre-term infants compared with full-term infants. The primary objective of this study was to describe parents 'perceptions of developmental eating patterns and occurrence of eating difficulties in a group of pre-term infants, compared with a control group. A parent questionnaire was administered for a study group (27 pre-term infants born between 28-33 weeks gestation) and a control group (29 full-term infants born between 38-41 weeks gestation). Parents of the pre-term children reported significantly more problems with early feeding, but only half of them reported that their infants received intervention to aid their feeding development during neonatal care. At 3 years of age the pre-term children weighed significantly less than the full-term children, but their parents were more satisfied with their eating habits and portion sizes than the control group parents. This finding may reflect differing parenting experiences between the two groups rather than an actual difference in eating skills. It suggests that parents of pre-term infants would benefit from practical guidance in supporting their premature infants in developing eating skills. Future studies using objective measures are recommended to verify the findings reported here.

Place, publisher, year, edition, pages
Informa Healthcare, 2013
Keywords
Feeding problems, eating problems, pre-term infants
National Category
Pediatrics
Research subject
Pediatrics
Identifiers
urn:nbn:se:umu:diva-81496 (URN)10.3109/17549507.2013.808699 (DOI)000326970100006 ()24007388 (PubMedID)
Available from: 2013-10-14 Created: 2013-10-14 Last updated: 2018-08-09Bibliographically approved
Karlsson, F., Olofsson, K., Blomstedt, P., Linder, J. & Doorn, J. v. (2013). Pitch variability in patients with Parkinson’s disease: effects of deep brain stimulation of caudal zona incerta and subthalamic nucleus. Journal of Speech, Language and Hearing Research, 56(1), 150-158
Open this publication in new window or tab >>Pitch variability in patients with Parkinson’s disease: effects of deep brain stimulation of caudal zona incerta and subthalamic nucleus
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2013 (English)In: Journal of Speech, Language and Hearing Research, ISSN 1092-4388, E-ISSN 1558-9102, Vol. 56, no 1, p. 150-158Article in journal (Refereed) Published
Abstract [en]

Objective The purpose of the present study was to examine the effect of deep brain stimulation (DBS) of the subthalamic nucleus (STN) and the caudal zona incerta (cZi) pitch characteristics of con- nected speech in patients with Parkinson’s disease (PD).

Methods Sixteen patients were evaluated preoperatively and 12 months after DBS surgery. Eight pa- tients were implanted in the STN (aged 51-72 yrs; xC=63 yrs). Six received bilateral implanta- tion and two unilateral (left) implantation. Eight patients were bilaterally implanted in the cZi (aged 49-71 yrs; xC=60.8 yrs). Preoperative assessments were made after an L-Dopa challenge (approximately 1.5 times the ordinary dose). All postoperative examinations were made off and on stimulation, with a clinically optimized dose of L-dopa. Measurements of pitch range and var- iability were obtained from each utterance in a recorded read speech passage.

Results Pitch range and coefficient of variation showed an increase in patients under STN-DBS. Patients under cZi-DBS showed no significant effects of treatment on investigated pitch properties.

Conclusions STN-DBS was shown to increase pitch variation and range. The results provided no evidence of cZi-DBS having a beneficial effect on PD patients’ pitch variability. 

Place, publisher, year, edition, pages
American Speech-Language-Hearing Association, 2013
National Category
Neurology Otorhinolaryngology
Research subject
Linguistics; Neurology; Neurosurgery; Oto-Rhino-Laryngology
Identifiers
urn:nbn:se:umu:diva-58210 (URN)10.1044/1092-4388(2012/11-0333) (DOI)000322444900012 ()
Projects
En kontrastiv och longitudinell studie gällande effekten av djup hjärnstimulering på Parkinsons-patienters artikulatoriska förmåga.Intonation och rytm i talet hos personer med Parkinsons sjukdom - en longitudinell jämförelse mellan sjukdomens effekter och effekter av behandling
Funder
Swedish Research Council, 2009-946Swedish Research Council, 2011-2294
Available from: 2012-08-28 Created: 2012-08-27 Last updated: 2018-06-08Bibliographically approved
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