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Zeisig, Eva
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Publications (10 of 10) Show all publications
Ferry, T., Bergström, U., Hedström, E. M., Lorentzon, R. & Zeisig, E. (2014). Epidemiology of acute knee injuries seen at the Emergency Department at Umeå University Hospital, Sweden, during 15 years. Knee Surgery, Sports Traumatology, Arthroscopy, 22(5), 1149-1155
Open this publication in new window or tab >>Epidemiology of acute knee injuries seen at the Emergency Department at Umeå University Hospital, Sweden, during 15 years
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2014 (English)In: Knee Surgery, Sports Traumatology, Arthroscopy, ISSN 0942-2056, E-ISSN 1433-7347, Vol. 22, no 5, p. 1149-1155Article in journal (Refereed) Published
Abstract [en]

PURPOSE: To describe the incidence and injury distribution of knee injuries in the general population of a European setting. METHODS: Retrospective study of all knee injuries registered at the Emergency Department at Umeå University Hospital, Sweden, during 1995-2009 in relation to age, sex, diagnosis, location and activity at the time of injury, mechanism of injury, and treatment and/or follow-up plan. RESULTS: During 1995-2009, 12,663 knee injuries were registered, 8 % of all injuries. The incidence of knee injuries resulting in a visit to the Emergency Department was six cases per 1,000 person years. One-third of all injuries occurred during sports. And 30 % were 15-24 years. More men than women were injured during sporting activities and women were mostly injured during transportation. CONCLUSION: Knee injuries in a general population are common and the injury distribution varies with age and sex. Sports activities and young age were prominent features of the injured population. LEVEL OF EVIDENCE: IV.

Place, publisher, year, edition, pages
Springer, 2014
Keywords
knee injury, general population, epidemiology, incidence, sports
National Category
Orthopaedics Sport and Fitness Sciences Surgery
Identifiers
urn:nbn:se:umu:diva-79211 (URN)10.1007/s00167-013-2555-3 (DOI)000334757600026 ()23740325 (PubMedID)
Available from: 2013-08-13 Created: 2013-08-13 Last updated: 2018-06-08Bibliographically approved
Zeisig, E. (2012). Natural course in tennis elbow-lateral epicondylitis after all?. Knee Surgery, Sports Traumatology, Arthroscopy, 20(12), 2549-2552
Open this publication in new window or tab >>Natural course in tennis elbow-lateral epicondylitis after all?
2012 (English)In: Knee Surgery, Sports Traumatology, Arthroscopy, ISSN 0942-2056, E-ISSN 1433-7347, Vol. 20, no 12, p. 2549-2552Article in journal (Refereed) Published
Abstract [en]

Tennis elbow is a common and difficult-to-treat condition largely because of lack of evidence. The natural history is unknown, but the condition is described as self-limiting. The objective of this case report is to describe the natural course of two control participants (pain free), who later developed tennis elbow, patient history, clinical findings, and ultrasound and colour Doppler examination before, during and after a period of tennis elbow.

Place, publisher, year, edition, pages
Springer Berlin/Heidelberg, 2012
Keywords
Tennis elbow, Ultrasonography, Natural course, Enthesophyte
National Category
Orthopaedics
Identifiers
urn:nbn:se:umu:diva-55449 (URN)10.1007/s00167-012-1939-0 (DOI)22434158 (PubMedID)
Available from: 2012-05-15 Created: 2012-05-15 Last updated: 2018-06-08Bibliographically approved
Zeisig, E., Fahlström, M., Öhberg, L. & Alfredson, H. (2010). A 2-year sonographic follow-up after intratendinous injection therapy in patients with tennis elbow. British Journal of Sports Medicine, 44(8), 584-587
Open this publication in new window or tab >>A 2-year sonographic follow-up after intratendinous injection therapy in patients with tennis elbow
2010 (English)In: British Journal of Sports Medicine, ISSN 0306-3674, E-ISSN 1473-0480, Vol. 44, no 8, p. 584-587Article in journal (Refereed) Published
Abstract [en]

Background Tennis elbow is a tendinopathy affecting the upper extremity. Recent studies have shown high sensitivity for ultrasound (US) examination and high specificity for colour Doppler (CD) examination. There are no mid- or long-term follow-up investigations of the tendon structure and blood flow using these techniques.

Objective To use US and CD to study structure and blood flow in the extensor origin in patients with tennis elbow treated with intratendinous injections.

Design Follow-up study

Setting Sports Medicine Unit, Umeå University.

Patients 25 patients (28 elbows), mean age 46 years (range 27–66), treated with intratendinous injections due to chronic pain from tennis elbow.

Method US and CD examination of the extensor origin was carried out at inclusion and at follow-up two years after intratendinous injection treatment with polidocanol and/or a local anaesthetic.

Main outcome measurements US (structure) and CD (blood flow) findings.

Results All patients had structural tendon changes and high blood flow at inclusion when given the injection treatment. At the two-year follow-up, structural tendon changes were seen in 20/28 elbows and high blood flow was seen in 4/28 elbows. The majority of patients with a good clinical result after treatment had no visible blood flow (17/20), but the structural changes showed no relation to a good result (13/20 remaining changes).

Conclusions Doppler findings, but not structure, might be related to the clinical result after intratendinous injection treatment of tennis elbow.

Place, publisher, year, edition, pages
BMJ Publishing Group, 2010
Keywords
Tennis elbow, injection treatment
National Category
Medical and Health Sciences Sport and Fitness Sciences
Research subject
Rehabilitation Medicine
Identifiers
urn:nbn:se:umu:diva-3483 (URN)10.1136/bjsm.2008.049874 (DOI)000278712200010 ()
Available from: 2008-09-22 Created: 2008-09-22 Last updated: 2018-06-09Bibliographically approved
Rabago, D., Best, T. M., Zgierska, A. E., Zeisig, E., Ryan, M. & Crane, D. (2009). A systematic review of four injection therapies for lateral epicondylosis: prolotherapy, polidocanol, whole blood and platelet-rich plasma. British Journal of Sports Medicine, 43(7), 471-481
Open this publication in new window or tab >>A systematic review of four injection therapies for lateral epicondylosis: prolotherapy, polidocanol, whole blood and platelet-rich plasma
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2009 (English)In: British Journal of Sports Medicine, ISSN 0306-3674, E-ISSN 1473-0480, Vol. 43, no 7, p. 471-481Article, review/survey (Refereed) Published
Abstract [en]

OBJECTIVE: To appraise existing evidence for prolotherapy, polidocanol, autologous whole blood and platelet-rich plasma injection therapies for lateral epicondylosis (LE). DESIGN: Systematic review. DATA SOURCES: Medline, Embase, CINAHL, Cochrane Central Register of Controlled Trials, Allied and Complementary Medicine. Search strategy: names and descriptors of the therapies and LE. STUDY SELECTION: All human studies assessing the four therapies for LE. MAIN RESULTS: Results of five prospective case series and four controlled trials (three prolotherapy, two polidocanol, three autologous whole blood and one platelet-rich plasma) suggest each of the four therapies is effective for LE. In follow-up periods ranging from 9 to 108 weeks, studies reported sustained, statistically significant (p<0.05) improvement in visual analogue scale primary outcome pain score measures and disease-specific questionnaires; relative effect sizes ranged from 51% to 94%; Cohen's d ranged from 0.68 to 6.68. Secondary outcomes also improved, including biomechanical elbow function assessment (polidocanol and prolotherapy), presence of abnormalities and increased vascularity on ultrasound (autologous whole blood and polidocanol). Subjects reported satisfaction with therapies on single-item assessments. All studies were limited by small sample size. CONCLUSIONS: There is strong pilot-level evidence supporting the use of prolotherapy, polidocanol, autologous whole blood and platelet-rich plasma injections in the treatment of LE. Rigorous studies of sufficient sample size, assessing these injection therapies using validated clinical, radiological and biomechanical measures, and tissue injury/healing-responsive biomarkers, are needed to determine long-term effectiveness and safety, and whether these techniques can play a definitive role in the management of LE and other tendinopathies.

National Category
Sport and Fitness Sciences
Identifiers
urn:nbn:se:umu:diva-32890 (URN)10.1136/bjsm.2008.052761 (DOI)000267724100002 ()19028733 (PubMedID)
Available from: 2010-03-30 Created: 2010-03-30 Last updated: 2018-06-08Bibliographically approved
Zeisig, E., Ljung, B.-O., Alfredson, H. & Danielson, P. (2009). Immunohistochemical evidence of local production of catecholamines in cells of the muscle origins at the lateral and medial humeral epicondyles: of importance for the development of tennis and golfer's elbow?. British Journal of Sports Medicine, 43(4), 269-275
Open this publication in new window or tab >>Immunohistochemical evidence of local production of catecholamines in cells of the muscle origins at the lateral and medial humeral epicondyles: of importance for the development of tennis and golfer's elbow?
2009 (English)In: British Journal of Sports Medicine, ISSN 0306-3674, E-ISSN 1473-0480, Vol. 43, no 4, p. 269-275Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Tennis elbow (TE) is a painful condition affecting the common extensor origin at the lateral humeral epicondyle. Colour Doppler examination has shown increased blood flow at this site and the sensory, and sympathetic innervation patterns have been delineated. However, it is not known whether there is local production of catecholamines and/or acetylcholine in this tissue, which is the case in patellar and Achilles tendinopathies. OBJECTIVE: To investigate the possible presence of local production of catecholamines and acetylcholine in non-neuronal cells (fibroblasts) in connective tissue at the muscle origin at the lateral humeral epicondyle in patients with TE. DESIGN: Immunohistochemical studies were performed on biopsies taken from the extensor origin in patients with TE and in pain-free controls. For reference purpose, biopsies from the flexor origin in patients with golfer's elbow (GE) were also studied. PATIENTS: Seven patients with TE and four patients with GE. Six healthy asymptomatic individuals served as controls. Method: Immunohistochemistry, using antibodies detecting synthesising enzymes for catecholamines (tyrosine hydroxylase; TH) and acetylcholine (choline acetyltransferase; ChAT). RESULTS: TH-like immunohistochemical reactions were seen in fibroblasts in four of the seven patients with TE and two of the four patients with GE. No such reactions were detected in controls (0/6). No ChAT reactions were seen in any of the investigated specimens. CONCLUSIONS: There is evidence of local, non-neuronal production of catecholamines, but not acetylcholine, in fibroblasts in the tissue at the muscle origin at the lateral and medial epicondyles in patients with TE and GE, respectively, which might have an influence on blood vessel regulation and pain mechanisms in these conditions.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:umu:diva-32029 (URN)10.1136/bjsm.2008.054619 (DOI)19155232 (PubMedID)
Available from: 2010-02-26 Created: 2010-02-26 Last updated: 2018-06-08Bibliographically approved
Alfredson, H., Zeisig, E. & Fahlström, M. (2009). No normalisation of the tendon structure and thickness after intratendinous surgery for chronic painful midportion Achilles tendinosis.. British journal of sports medicine, 43(12), 948-9
Open this publication in new window or tab >>No normalisation of the tendon structure and thickness after intratendinous surgery for chronic painful midportion Achilles tendinosis.
2009 (English)In: British journal of sports medicine, ISSN 1473-0480, Vol. 43, no 12, p. 948-9Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: To characterise Achilles tendon structure and thickness a minimum of 8 years after intra-tendinous surgery. Material and METHODS: Fourteen patients (16 tendons; 9 men and 5 women, mean age 43 years, range 27-55) surgically treated (intra-tendinous surgery) for chronic painful midportion Achilles tendinosis, were followed with clinical examination and grey-scale ultrasonography for a minimum of 8 years (range 8-16 years, mean 13 years). RESULTS: All patients were satisfied with the result of surgery and were active in Achilles tendon loading activities without restrictions. In all operated tendons, structural abnormalities remained and tendons remained thicker than normal tendons. CONCLUSIONS: Resection of tendinosis is associated with persistent structural abnormalities and thickening of the tendon 13 years after surgery, despite successful clinical outcomes.

National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:umu:diva-26614 (URN)10.1136/bjsm.2008.050955 (DOI)18927167 (PubMedID)
Available from: 2009-10-16 Created: 2009-10-16 Last updated: 2018-06-08
Zeisig, E., Fahlström, M., Öhberg, L. & Alfredson, H. (2008). Pain relief after intratendinous injections in patients with tennis elbow: results of a randomised study. British Journal of Sports Medicine, 42(4), 267-271
Open this publication in new window or tab >>Pain relief after intratendinous injections in patients with tennis elbow: results of a randomised study
2008 (English)In: British Journal of Sports Medicine, ISSN 0306-3674, E-ISSN 1473-0480, Vol. 42, no 4, p. 267-271Article in journal (Refereed) Published
National Category
Sport and Fitness Sciences
Identifiers
urn:nbn:se:umu:diva-3482 (URN)10.1136/bjsm.2007.042762 (DOI)
Available from: 2008-09-22 Created: 2008-09-22 Last updated: 2018-06-09Bibliographically approved
Alfredson, H., Öhberg, L., Zeisig, E. & Lorentzon, R. (2007). Treatment of midportion Achilles tendinosis: similar clinical results with US and CD-guided surgery outside the tendon and sclerosing polidocanol injections.. Knee Surg Sports Traumatol Arthrosc, 15(12), 1504-1509
Open this publication in new window or tab >>Treatment of midportion Achilles tendinosis: similar clinical results with US and CD-guided surgery outside the tendon and sclerosing polidocanol injections.
2007 (English)In: Knee Surg Sports Traumatol Arthrosc, ISSN 0942-2056, Vol. 15, no 12, p. 1504-1509Article in journal (Refereed) Published
Keywords
Achilles, Chronic pain, Sclerosing injections, Surgery
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:umu:diva-10139 (URN)doi:10.1007/s00167-007-0415-8 (DOI)17879083 (PubMedID)
Available from: 2008-06-19 Created: 2008-06-19 Last updated: 2018-06-09Bibliographically approved
Zeisig, E., Öhberg, L. & Alfredson, H. (2006). Extensor origin vascularity related to pain in patients with Tennis elbow. Knee Surgery, Sports Traumatology, Arthroscopy, 14(7), 659-663
Open this publication in new window or tab >>Extensor origin vascularity related to pain in patients with Tennis elbow
2006 (English)In: Knee Surgery, Sports Traumatology, Arthroscopy, ISSN 0942-2056, E-ISSN 1433-7347, Vol. 14, no 7, p. 659-663Article in journal (Refereed) Published
Keywords
Anesthetics; Local/administration & dosage, Blood Flow Velocity, Case-Control Studies, Female, Hand Strength, Humans, Injections; Intra-Articular, Lidocaine/administration & dosage, Male, Middle Aged, Pain Measurement, Tendons/*blood supply/*ultrasonography, Tennis Elbow/*physiopathology/*ultrasonography, Ultrasonography/methods, Weight-Bearing
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:umu:diva-3480 (URN)10.1007/s00167-006-0060-7 (DOI)
Available from: 2008-09-22 Created: 2008-09-22 Last updated: 2018-06-09Bibliographically approved
Zeisig, E., Öhberg, L. & Alfredson, H. (2006). Sclerosing polidocanol injections in chronic painful tennis elbow: promising results in a pilot study. Knee Surgery, Sports Traumatology, Arthroscopy, 14(11), 1218-1224
Open this publication in new window or tab >>Sclerosing polidocanol injections in chronic painful tennis elbow: promising results in a pilot study
2006 (English)In: Knee Surgery, Sports Traumatology, Arthroscopy, ISSN 0942-2056, E-ISSN 1433-7347, Vol. 14, no 11, p. 1218-1224Article in journal (Refereed) Published
Keywords
Adult, Arthralgia/*therapy/ultrasonography, Chronic Disease, Female, Follow-Up Studies, Humans, Injections; Intra-Articular, Male, Middle Aged, Patient Satisfaction, Pilot Projects, Polyethylene Glycols/*therapeutic use, Sclerosing Solutions/*therapeutic use, Tendons/blood supply/innervation, Tennis Elbow/*therapy/ultrasonography, Treatment Outcome, Ultrasonography; Doppler; Color, Ultrasonography; Interventional
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:umu:diva-3481 (URN)10.1007/s00167-006-0156-0 (DOI)
Available from: 2008-09-22 Created: 2008-09-22 Last updated: 2018-06-09Bibliographically approved
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