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Norström, Sara H.
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Publications (2 of 2) Show all publications
Blum, K. M., Norström, S. H., Golovko, O., Grabic, R., Järhult, J. D., Koba, O. & Söderström Lindström, H. (2017). Removal of 30 active pharmaceutical ingredients in surface water under long-term artificial UV irradiation. Chemosphere, 176, 175-182
Open this publication in new window or tab >>Removal of 30 active pharmaceutical ingredients in surface water under long-term artificial UV irradiation
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2017 (English)In: Chemosphere, ISSN 0045-6535, E-ISSN 1879-1298, Vol. 176, p. 175-182Article in journal (Refereed) Published
Abstract [en]

This study investigated the i) kinetics, and ii) proportion of photolysis of 30 relatively stable active pharmaceutical ingredients (APIs) during artificial UV irradiation for 28 d in ammonium acetate buffer, filtered and unfiltered river water. Buffer was included to control removal kinetics under stable pH conditions and without particulate matter. Dark controls were used to determine removal due to other processes than photolysis and calculate the proportion of photolysis of the total removal. The removal of each API in each matrix was determined using online solid phase extraction/liquid chromatography tandem mass spectrometry (online SPE/LC-MS/MS). Most APIs transformed during the 28 d of UV irradiation and the dark controls showed that photolysis was the major removal process for the majority of the APIs studied. The half-lives ranged from 6 h (amitriptyline) in unfiltered river water to 884 h (37 d, carbamazepine) in buffer. In unfiltered river water, the proportion of APIs with short half-lives (<48 h) was much higher (29%) than in the other matrices (4%), probably due to additional organic carbon, which could have promoted indirect photolysis. Furthermore, two APIs, memantine and fluconazole, were stable in all three matrices, while alprazolam was stable in buffer and unfiltered river water and four additional APIs were stable in buffer. Considering the relatively long-term UV-exposure, this study enabled the investigation of environmentally relevant half-lives in natural waters. Many APIs showed high persistence, which is environmentally concerning and emphasizes the importance of further studies on their environmental fate and effects.

Place, publisher, year, edition, pages
Elsevier, 2017
Active pharmaceutical ingredients, Oseltamivir, Photostability, Photolysis, Half-lives, Aquatic environments
National Category
Environmental Sciences
urn:nbn:se:umu:diva-132650 (URN)10.1016/j.chemosphere.2017.02.063 (DOI)000399849300021 ()

Corrigendum: Kristin M. Blum, Sara H. Norström, Oksana Golovko, Roman Grabic, Josef D. Järhult, Olga Koba, Hanna Söderström Lindström. Corrigendum to “Removal of 30 active pharmaceutical ingredients in surface water under long-term artificial UV irradiation”. Chemosphere. 2018;208. DOI: 10.1016/j.chemosphere.2018.05.150

Available from: 2017-03-20 Created: 2017-03-20 Last updated: 2018-09-11Bibliographically approved
Fransson, P., Andersson, A., Norström, S., Bylund, D. & Bent, E. (2016). Ectomycorrhizal exudates and pre-exposure to elevated CO2 affects soil bacterial growth and community structure. Fungal ecology, 20, 211-224
Open this publication in new window or tab >>Ectomycorrhizal exudates and pre-exposure to elevated CO2 affects soil bacterial growth and community structure
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2016 (English)In: Fungal ecology, ISSN 1754-5048, E-ISSN 1878-0083, Vol. 20, p. 211-224Article in journal (Refereed) Published
Abstract [en]

Ectomycorrhizal fungi produce low molecular weight organic compounds, supporting diverse microbial communities. To link mycorrhizal root exudation directly to bacterial responses, we used Scots pine exudates with (Suillus variegatus and Piloderma fallax) and without mycorrhiza as substrata for forest soil bacteria. Bacterial growth and vitality was monitored, and community composition determined using TRFLP, cloning and sequencing. We investigated if the amount of organic acids in exudates explained bacterial growth, and whether bacterial communities were influenced by pre-exposure to elevated atmospheric CO2. We demonstrated functional differences in bacterial growth rates related to CO2. There was a shift in the bacterial community (e.g. Burkholderia sp. and gamma-proteobacteria) toward organisms better able to rapidly utilize exudates when pine microcosms were pre-exposed to elevated CO2. Soil bacteria from all treatments tended to grow more abundantly and rapidly in exudates from Pilo derma -colonized seedlings, suggesting that the organic acids and/or unidentified compounds present supported greater growth.

Place, publisher, year, edition, pages
Elsevier, 2016
Exudation, Organic acids, Mycorrhiza, Burkholderia, Suillus, Piloderma, Soil microbes, Nonmycorrhizal, Soil microbiome
National Category
Environmental Sciences Ecology
urn:nbn:se:umu:diva-130038 (URN)10.1016/j.funeco.2016.01.003 (DOI)000373539100026 ()
Available from: 2017-01-11 Created: 2017-01-11 Last updated: 2018-06-09Bibliographically approved

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