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Finn, Fia
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Hellström, G., Klaminder, J., Finn, F., Persson, L., Alanärä, A., Jonsson, M., . . . Brodin, T. (2016). GABAergic anxiolytic drug in water increases migration behaviour in salmon. Nature Communications, 7, Article ID 13460.
Open this publication in new window or tab >>GABAergic anxiolytic drug in water increases migration behaviour in salmon
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2016 (English)In: Nature Communications, ISSN 2041-1723, E-ISSN 2041-1723, Vol. 7, article id 13460Article in journal (Refereed) Published
Abstract [en]

Migration is an important life-history event in a wide range of taxa, yet many migrations are influenced by anthropogenic change. Although migration dynamics are extensively studied, the potential effects of environmental contaminants on migratory physiology are poorly understood. In this study we show that an anxiolytic drug in water can promote downward migratory behaviour of Atlantic salmon (Salmo salar) in both laboratory setting and in a natural river tributary. Exposing salmon smolt to a dilute concentration of a GABAA receptor agonist (oxazepam) increased migration intensity compared with untreated smolt. These results implicate that salmon migration may be affected by human-induced changes in water chemical properties, such as acidification and pharmaceutical residues in wastewater effluent, via alterations in the GABAA receptor function.

Place, publisher, year, edition, pages
Nature Publishing Group, 2016
National Category
Environmental Sciences Pharmacology and Toxicology
Identifiers
urn:nbn:se:umu:diva-130084 (URN)10.1038/ncomms13460 (DOI)000389265400001 ()
Available from: 2017-01-13 Created: 2017-01-11 Last updated: 2018-06-09Bibliographically approved
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