Change search
ExportLink to record
Permanent link

Direct link


Project type/Form of grant
Project grant
Title [sv]
CELIAKI. ÄR DET DAGS FÖR PRIMÄR PREVENTION OCH ALLMÄN SCREENING? En studie av 12-åringar födda under epidemin och åren därefter.
Title [en]
CELIAC DISEASE. HAS THE TIME COME FOR PRIMARY PREVENTION AND MASS SCREENING? Evaluation of the Swedish epidemic and post-epidemic cohorts at twelve-years-of-age.
Abstract [sv]
Celiac disease (CD) is common and often unrecognised with negative health consequences. Treatment implies lifelong exclusion of all food with gluten (wheat, rye and barley). Sweden has experienced a CD epidemic, with no likeness anywhere in the world, partly explained by changes in infant feeding. This provides a unique opportunity to evaluate if primary prevention of CD is possible (aim 1), and to explore any relation between gluten ingestion and other autoimmune diseases (aim 2). Most CD cases will only be diagnosed through mass screening programs, which need to be evaluated considering consequences for individuals and society (aim 3). The ETICS study - Exploring the Iceberg of Celiacs in Sweden ? is an ongoing multicenter project requiring a dedicated and long-term effort. Cornerstones are two CD screening efforts (2005-2006 and 2009-2010) involving 17 608 12-year-olds, and with 1- and 5 year follow-up studies. Data collection includes blood samples, weight and height, questionnaires (with validated instruments), narratives, and focus groups. We have successfully completed both CD screening field phases, while the follow-up studies remain. Data compiled are extensive and will allow us to elucidate the questions of primary prevention and any association between gluten ingestion and autoimmunity. We will also clarify whether CD mass screening is a wise use of resources. Results reported so far have attracted great interest both nationally and internationally.
Principal InvestigatorIvarsson, Anneli
Coordinating organisation
Umeå University
2012-01-01 - 2014-12-31
National Category
Gastroenterology and HepatologyPublic Health, Global Health, Social Medicine and Epidemiology
DiVA, id: project:1156Project, id: 2011-03248_VR