umu.sePublikasjoner
Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Using laboratory incubations to predict the fate of pharmaceuticals in aquatic ecosystems
Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Institutionen för ekologi, miljö och geovetenskap.
Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Kemiska institutionen.ORCID-id: 0000-0002-3949-7371
Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Institutionen för ekologi, miljö och geovetenskap.ORCID-id: 0000-0001-5730-0694
Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Institutionen för ekologi, miljö och geovetenskap.ORCID-id: 0000-0002-1618-2617
Vise andre og tillknytning
2018 (engelsk)Inngår i: Environmental Chemistry, ISSN 1448-2517, E-ISSN 1449-8979, Vol. 15, nr 8, s. 463-471Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Environmental contextEnvironmental persistence of excreted pharmaceuticals in aquatic ecosystems is usually predicted using small-scale laboratory experiments assumed to simulate natural conditions. We studied five pharmaceuticals comparing their removal rates from water under laboratory conditions and under natural environmental conditions existing in a large pond. We found that the laboratory conditions did not fully capture the complexity within the pond, which led to different removal rates in the two systems. AbstractEnvironmental persistence is a key property when evaluating risks with excreted pharmaceuticals in aquatic ecosystems. Such persistence is typically predicted using small-scale laboratory incubations, but the variation in aquatic environments and scarcity of field studies to verify laboratory-based persistence estimates create uncertainties around the predictive power of these incubations. In this study we: (1) assess the persistence of five pharmaceuticals (diclofenac, diphenhydramine, hydroxyzine, trimethoprim and oxazepam) in laboratory experiments under different environmental conditions; and (2) use a three-month-long field study in an aquatic ecosystem to verify the laboratory-based persistence estimates. In our laboratory assays, we found that water temperature (TEMP), concentrations of organic solutes (TOC), presence of sediment (SED), and solar radiation (SOL) individually affected dissipation rates. Moreover, we identified rarely studied interaction effects between the treatments (i.e. SOLxSED and TEMPxSOL), which affected the persistence of the studied drugs. Half-lives obtained from the laboratory assays largely explained the dissipation rates during the first week of the field study. However, none of the applied models could accurately predict the long-term dissipation rates (month time-scale) from the water column. For example, the studied antibioticum (trimethoprim) and the anti-anxiety drug (oxazepam) remained at detectable levels in the aquatic environment long after (similar to 150 days) our laboratory based models predicted complete dissipation. We conclude that small-scale laboratory incubations seem sufficient to approximate the short-term (i.e. within a week) dissipation rate of drugs in aquatic ecosystems. However, this simplistic approach does not capture interacting environmental processes that preserve a fraction of the dissolved pharmaceuticals for months in natural water bodies.

sted, utgiver, år, opplag, sider
CSIRO Publishing, 2018. Vol. 15, nr 8, s. 463-471
Emneord [en]
antibiotics, antidepressant, anxiolytics, antihistamines, degradation
HSV kategori
Identifikatorer
URN: urn:nbn:se:umu:diva-154903DOI: 10.1071/EN18154ISI: 000452149900001OAI: oai:DiVA.org:umu-154903DiVA, id: diva2:1275048
Tilgjengelig fra: 2019-01-04 Laget: 2019-01-04 Sist oppdatert: 2019-01-04bibliografisk kontrollert

Open Access i DiVA

Fulltekst mangler i DiVA

Andre lenker

Forlagets fulltekst

Personposter BETA

Fahlman, JohanFick, JerkerKarlsson, JanJonsson, MicaelBrodin, TomasKlaminder, Jonatan

Søk i DiVA

Av forfatter/redaktør
Fahlman, JohanFick, JerkerKarlsson, JanJonsson, MicaelBrodin, TomasKlaminder, Jonatan
Av organisasjonen
I samme tidsskrift
Environmental Chemistry

Søk utenfor DiVA

GoogleGoogle Scholar

doi
urn-nbn

Altmetric

doi
urn-nbn
Totalt: 100 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf