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Long-Term Exposure to Particulate Air Pollution, Black Carbon, and Their Source Components in Relation to Ischemic Heart Disease and Stroke
Vise andre og tillknytning
2019 (engelsk)Inngår i: Journal of Environmental Health Perspectives, ISSN 0091-6765, E-ISSN 1552-9924, Vol. 127, nr 10, artikkel-id 107012Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

BACKGROUND: Long-term exposure to particulate matter (PM) in ambient air has been associated with cardiovascular mortality, but few studies have considered incident disease in relation to PM from different sources.

OBJECTIVES: We aimed to study associations between long-term exposure to different types of PM and sources, and incident ischemic heart disease (IHD) and stroke in three Swedish cities.

METHODS: ), and black carbon (BC) from road wear, traffic exhaust, residential heating, and other sources in Gothenburg, Stockholm, and Umeå. Registry data for participants from four cohorts were used to obtain incidence of IHD and stroke for first hospitalization or death. We constructed time windows of exposure for same-year, 1- to 5-y, and 6- to 10-y averages preceding incidence from annual averages at residential addresses. Risk estimates were based on random effects meta-analyses of cohort-specific Cox proportional hazard models.

RESULTS: exposure from residential heating.

DISCUSSION: Few consistent associations were observed between different particulate components and IHD or stroke. However, long-term residential exposure to locally emitted BC from traffic exhaust was associated with stroke incidence. The comparatively low exposure levels may have contributed to the paucity of associations.

sted, utgiver, år, opplag, sider
Durham: National Institute of Environmental Health Sciences , 2019. Vol. 127, nr 10, artikkel-id 107012
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Identifikatorer
URN: urn:nbn:se:umu:diva-164779DOI: 10.1289/EHP4757ISI: 000500762300003PubMedID: 31663781OAI: oai:DiVA.org:umu-164779DiVA, id: diva2:1367117
Forskningsfinansiär
Swedish Research Council, 2013-5187Swedish Research Council, 2017-00641Stockholm County CouncilNovo NordiskNIH (National Institute of Health), 1R01 AG08724Västerbotten County CouncilForte, Swedish Research Council for Health, Working Life and Welfare, 2015-00917Tilgjengelig fra: 2019-11-01 Laget: 2019-11-01 Sist oppdatert: 2020-01-03bibliografisk kontrollert

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Sommar, JohanWennberg, PatrikForsberg, Bertil

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