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Consumption of nuts and seeds and pancreatic ductal adenocarcinoma risk in the European Prospective Investigation into Cancer and Nutrition
Vise andre og tillknytning
2020 (engelsk)Inngår i: International Journal of Cancer, ISSN 0020-7136, E-ISSN 1097-0215, Vol. 146, nr 1, s. 76-84Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Four epidemiologic studies have assessed the association between nut intake and pancreatic cancer risk with contradictory results. The present study aims to investigate the relation between nut intake (including seeds) and pancreatic ductal adenocarcinoma (PDAC) risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Cox proportional hazards models were used to estimate hazards ratio (HR) and 95% confidence intervals (95% CI) for nut intake and PDAC risk. Information on intake of nuts was obtained from the EPIC country-specific dietary questionnaires. After a mean follow-up of 14 years, 476,160 participants were eligible for the present study and included 1,283 PDAC cases. No association was observed between consumption of nuts and PDAC risk (highest intake vs nonconsumers: HR, 0.89; 95% CI, 0.72-1.10; p-trend = 0.70). Furthermore, no evidence for effect-measure modification was observed when different subgroups were analyzed. Overall, in EPIC, the highest intake of nuts was not statistically significantly associated with PDAC risk.

sted, utgiver, år, opplag, sider
Wiley-Blackwell, 2020. Vol. 146, nr 1, s. 76-84
Emneord [en]
pancreatic cancer, nuts, seeds, diet, intake, EPIC, prospective cohort study
HSV kategori
Identifikatorer
URN: urn:nbn:se:umu:diva-165785DOI: 10.1002/ijc.32415ISI: 000495546500011PubMedID: 31107546OAI: oai:DiVA.org:umu-165785DiVA, id: diva2:1374892
Forskningsfinansiär
Swedish Cancer SocietyRegion SkåneVästerbotten County CouncilTilgjengelig fra: 2019-12-03 Laget: 2019-12-03 Sist oppdatert: 2019-12-03bibliografisk kontrollert

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Boutron-Ruault, Marie-ChristineOvervad, KimSciannameo, VeronicaSund, Malin
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