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[Autoimmune hepatitis often requires lifelong treatment]
Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Medicin.
Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Medicin.
2010 (svensk)Inngår i: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 107, nr 21, s. 1388-1391Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Autoimmune hepatitis (AIH) is a rare disease with an incidence of around 1 / 100,000 inhabitants, and a prevalence rate of 16 / 100,000. As many as 30 % of AIH-patients already have liver cirrhosis at diagnosis. The diagnosis is established with liver function tests of hepatocellular pattern, presence of autoimmune antibodies, increased polyclonal IgG, and a compatible liver biopsy. Mostly, immune suppressive treatment with corticosteroids alone or in combination with azathioprine brings the disease into remission. In cirrhotic patients there is an increased risk of hepatocellular cancer (HCC) with a SIR of 23.

sted, utgiver, år, opplag, sider
2010. Vol. 107, nr 21, s. 1388-1391
Emneord [en]
Hepatit, autoimmun, Lever, Autoantikroppar, Vävnadsprov, Prevalens, Incidens, Könsfördelning, Immunsuppression, Prednisolon, Budesonid, Azatioprin, Karcinom, hepatocellulärt
Identifikatorer
URN: urn:nbn:se:umu:diva-41404PubMedID: 20645615OAI: oai:DiVA.org:umu-41404DiVA, id: diva2:405901
Tilgjengelig fra: 2011-03-24 Laget: 2011-03-24 Sist oppdatert: 2017-12-11bibliografisk kontrollert

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