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Sonotrombolys kan förstärka effekten av intravenös trombolys
Umeå universitet, Medicinska fakulteten, Institutionen för farmakologi och klinisk neurovetenskap, Klinisk neurovetenskap.
Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Medicin.
Umeå universitet, Medicinska fakulteten, Institutionen för farmakologi och klinisk neurovetenskap, Klinisk neurovetenskap.
2015 (svensk)Inngår i: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 112, artikkel-id C9LFArtikkel, forskningsoversikt (Fagfellevurdert) Published
Abstract [sv]

Intravenous thrombolysis has been a break-through for treatment of acute ischemic stroke. However, total recanalization is only achieved in 18%. Sonothrombolysis aims at enhancing the recanalization effect by adding continuous transcranial ultrasound. Sonothrombolysis may facilitate the recanalization rate without increased risk of intracerebral hemorrhage. This further results in decreased risk of disability compared with only intravenous thrombolysis. Intravenously applied micro-bubbles is an additive treatment to sonothrombolysis which might further increase the recanalization rate but perhaps at the expense of increased risk of intracerebral hemorrhage. In a case-series at Umeå Stroke Center, we report the results of the first 20 ischemic stroke patients treated with sonothrombolysis in Sweden. Our initial results look promising with recanalization rates similar to earlier published data. No intracerebral hemorrhage occurred among our sonothrombolysed patients.

sted, utgiver, år, opplag, sider
2015. Vol. 112, artikkel-id C9LF
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URN: urn:nbn:se:umu:diva-113953PubMedID: 25647105OAI: oai:DiVA.org:umu-113953DiVA, id: diva2:892005
Tilgjengelig fra: 2016-01-08 Laget: 2016-01-08 Sist oppdatert: 2018-06-07bibliografisk kontrollert

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