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Cerebrospinal fluid dynamics and long-term survival of the Strata(®) valve in idiopathic normal pressure hydrocephalus.
Umeå universitet, Medicinska fakulteten, Institutionen för farmakologi och klinisk neurovetenskap, Neurologi.
Umeå universitet, Medicinska fakulteten, Institutionen för farmakologi och klinisk neurovetenskap, Neurokirurgi.
Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper, Diagnostisk radiologi.
Umeå universitet, Medicinska fakulteten, Institutionen för strålningsvetenskaper, Radiofysik.
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2011 (Engelska)Ingår i: Acta Neurologica Scandinavica, ISSN 0001-6314, E-ISSN 1600-0404, Vol. 124, nr 2, 115-121 s.Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Objective -  Cerebrospinal fluid (CSF) dynamics and long-term shunt survival of the Strata(®) CSF shunt were evaluated in patients with idiopathic normal pressure hydrocephalus (INPH). Subjects and methods -  Seventy-two patients with INPH received a Strata(®) valve. A CSF infusion test, neuroimaging and video recording of gait were performed at baseline and at 6 months (n = 68) after surgery. Long-term shunt survivals were obtained from patient records. Results -  The shunt survival at 1 year was 94% and at 3 years 92.5%. Forty-nine patients (72%) had an improved gait. Two patients were improved despite non-functioning shunts, indicating a possible placebo response. Nineteen patients were not improved at the 6-month follow-up. The shunt tests revealed a functioning shunt in 12; thus, unnecessary shunt revisions could be avoided. Seventeen patients showed a siphoning effect. Shunt revisions were made in six patients. Eight hygromas/subdural hematomas were found. Conclusions -  The long-term survival of the Strata(®) valves was good, and a concern of complications is not a reason to exclude elderly with INPH from shunt surgery. Studies are needed to evaluate pros and cons of the anti-siphon device. Using a CSF shunt test, unnecessary shunt revisions may be avoided.

Ort, förlag, år, upplaga, sidor
Wiley , 2011. Vol. 124, nr 2, 115-121 s.
Nyckelord [en]
normal pressure hydrocephalus, cerebrospinal fluid shunt, cerebrospinal fluid outflow conductance, cerebrospinal fluid infusion test, intracranial pressure
Identifikatorer
URN: urn:nbn:se:umu:diva-40870DOI: 10.1111/j.1600-0404.2010.01432.xPubMedID: 21039363OAI: oai:DiVA.org:umu-40870DiVA: diva2:403261
Tillgänglig från: 2011-03-11 Skapad: 2011-03-11 Senast uppdaterad: 2017-12-11Bibliografiskt granskad

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Lundkvist, BoKoskinen, Lars-OweBirgander, RichardEklund, AndersMalm, Jan
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NeurologiNeurokirurgiDiagnostisk radiologiRadiofysik
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