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The Swedish National Penile Cancer Register: Incidence, Tumour Characteristics, Management and Survival
Örebro, Sweden.
Umeå universitet, Medicinska fakulteten, Institutionen för kirurgisk och perioperativ vetenskap, Urologi och andrologi.
Umeå universitet, Medicinska fakulteten, Institutionen för kirurgisk och perioperativ vetenskap, Urologi och andrologi.
Uppsala, Sweden; Stockholm, Sweden.
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2016 (Engelska)Ingår i: BJU International, ISSN 1464-4096, E-ISSN 1464-410X, Vol. 117, nr 2, s. 287-292Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

OBJECTIVES:  To assess penile cancer incidence, stage distribution, adherence to guidelines, and prognostic factors in a population-based setting.

PATIENTS AND METHODS:  The population-based Swedish National Penile Cancer Register (NPECR) contains detailed information on tumour characteristics and management patterns. ● A total of 1678 men with primary squamous cell carcinoma of the penis identified in the NPECR between 2000 and 2012 were included in the study. 

RESULTS:  The mean age-adjusted incidence of penile cancer was 2.1/100,000 men, remaining virtually unchanged during the study period. At diagnosis, 14% and 2% were clinically N+ and M+, respectively. Most patients were staged pTis (34%), pT2 (19%), or pT1 (18%), whereas stage was unavailable in 18%. Organ-preserving treatment was used in 71% of Tis-T1 tumours. In cN0 and ≥pT1G2 patients, 50% underwent lymph node staging, while 74% of cN1-3 patients underwent lymph node dissection. The overall 5-year relative survival was 82%. Men aged ≥40 years and those with pT2-3, G2-3 and N+ tumours had worse outcome.

CONCLUSION: The incidence of penile cancer in Sweden is stable. Most men presented with localised disease, and the proportion of non-invasive tumours was high. During the period under study, adherence to guidelines was suboptimal. The overall 5-year relative survival was 82%. Older age, increasing tumour stage and grade, and increasing lymph node stage were associated with poorer survival.

Ort, förlag, år, upplaga, sidor
John Wiley & Sons, 2016. Vol. 117, nr 2, s. 287-292
Nyckelord [en]
penile cancer, population-based, incidence, TNM, prognostic factors, survival
Nationell ämneskategori
Cancer och onkologi
Identifikatorer
URN: urn:nbn:se:umu:diva-96583DOI: 10.1111/bju.12993ISI: 000367717300018PubMedID: 25395083OAI: oai:DiVA.org:umu-96583DiVA, id: diva2:765473
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Article first published online: 4 MAY 2015

Tillgänglig från: 2014-11-24 Skapad: 2014-11-24 Senast uppdaterad: 2018-06-07Bibliografiskt granskad

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Sherif, AmirFriedrich, Bengt

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