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The impact of adjusted work conditions and disease-modifying drugs on work ability in multiple sclerosis
Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience, Clinical Neuroscience.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Epidemiology and Global Health.
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2017 (English)In: Multiple Sclerosis Journal, ISSN 1352-4585, E-ISSN 1477-0970, Vol. 23, no 8, p. 1137-1147Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Multiple sclerosis (MS) is a neurological disorder that causes significantly reduced ability to work, and the Expanded Disability Status Scale (EDSS) is one of the main predictors for reduced work ability.

OBJECTIVES: To investigate how work requirements, flexible work conditions and disease-modifying drugs (DMDs) influence the work ability in relation to different EDSS grades in two MS populations.

METHODS: Work ability was studied in two MS populations: one in the southern and one in the northern part of Sweden, both demographically similar. In the latter population, more active work-promoting interventions have been practised and second-generation DMDs have been widely used from the onset of disease for several years.

RESULTS: The proportion of MS patients who participated in the workforce or studied was significantly higher in the northern compared with the southern population (p < 0.001). The employees in the northern population had significantly lower requirements, greater adapted work conditions and were able to work more hours per week. Higher EDSS was associated with lower reduction in number of worked hours per week in the northern population (p = 0.042).

CONCLUSION: Our data indicated that treatment strategy and adjusted work conditions have impact on work ability in MS.

Place, publisher, year, edition, pages
Sage Publications, 2017. Vol. 23, no 8, p. 1137-1147
Keywords [en]
Multiple sclerosis, disease-modifying drugs, working ability, work requirements, adjusted work conditions, Work Ability Questionnaire – Multiple Sclerosis
National Category
Public Health, Global Health, Social Medicine and Epidemiology Neurology
Identifiers
URN: urn:nbn:se:umu:diva-127490DOI: 10.1177/1352458516671818ISI: 000403588100050PubMedID: 27758955Scopus ID: 2-s2.0-85046070671OAI: oai:DiVA.org:umu-127490DiVA, id: diva2:1046496
Available from: 2016-11-14 Created: 2016-11-14 Last updated: 2023-03-23Bibliographically approved

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Wickström, AnneGranåsen, GabrielSundström, Peter

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