umu.sePublikasjoner
Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Metastatic spinal cord compression as the first sign of malignancy: Outcome after surgery in 69 patients
Umeå universitet, Medicinska fakulteten, Institutionen för kirurgisk och perioperativ vetenskap, Ortopedi.
Umeå universitet, Medicinska fakulteten, Institutionen för kirurgisk och perioperativ vetenskap, Ortopedi.
Umeå universitet, Medicinska fakulteten, Institutionen för samhällsmedicin och rehabilitering, Geriatrik.
Umeå universitet, Medicinska fakulteten, Institutionen för kirurgisk och perioperativ vetenskap, Ortopedi.
Vise andre og tillknytning
2017 (engelsk)Inngår i: Acta Orthopaedica, ISSN 1745-3674, E-ISSN 1745-3682, Vol. 88, nr 4, s. 457-462Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Background and purpose - Metastatic spinal cord compression (MSCC) as the initial manifestation of malignancy (IMM) limits the time for diagnostic workup; most often, treatment is required before the final primary tumor diagnosis. We evaluated neurological outcome, complications, survival, and the manner of diagnosing the primary tumor in patients who were operated for MSCC as the IMM.

Patients and methods - Records of 69 consecutive patients (51 men) who underwent surgery for MSCC as the IMM were reviewed. The patients had no history of cancer when they presented with pain (n = 2) and/or neurological symptoms (n = 67).

Results - The primary tumor was identified in 59 patients. In 10 patients, no specific diagnosis could be established, and they were therefore defined as having cancer of unknown primary tumor (CUP). At the end of the study, 16 patients were still alive (median follow-up 2.5 years). The overall survival time was 20 months. Patients with CUP had the shortest survival (3.5 months) whereas patients with prostate cancer (6 years) and myeloma (5 years) had the longest survival. 20 of the 39 patients who were non-ambulatory preoperatively regained walking ability, and 29 of the 30 ambulatory patients preoperatively retained their walking ability 1 month postoperatively. 15 of the 69 patients suffered from a total of 20 complications within 1 month postoperatively.

Interpretation - Postoperative survival with MSCC as the IMM depends on the type of primary tumor. Surgery in these patients maintains and improves ambulatory function.

sted, utgiver, år, opplag, sider
Taylor & Francis, 2017. Vol. 88, nr 4, s. 457-462
HSV kategori
Identifikatorer
URN: urn:nbn:se:umu:diva-137890DOI: 10.1080/17453674.2017.1319179ISI: 000404588400017PubMedID: 28492105OAI: oai:DiVA.org:umu-137890DiVA, id: diva2:1130418
Tilgjengelig fra: 2017-08-09 Laget: 2017-08-09 Sist oppdatert: 2018-06-09bibliografisk kontrollert

Open Access i DiVA

fulltext(304 kB)71 nedlastinger
Filinformasjon
Fil FULLTEXT01.pdfFilstørrelse 304 kBChecksum SHA-512
a2cfa4595eaf2ea37883fc22bee3714b20d5a96295aad0b6533a8606610f696e4cbfe482e6cb0ad082b6e6e0398e9c0d53e486a10f1b6c24d233c902dd5e3d9e
Type fulltextMimetype application/pdf

Andre lenker

Forlagets fulltekstPubMed

Personposter BETA

Grabowski, PawelNyström, HelenaGustafsson, PatrikBergh, AndersWidmark, AndersCrnalic, Sead

Søk i DiVA

Av forfatter/redaktør
Grabowski, PawelNyström, HelenaGustafsson, PatrikBergh, AndersWidmark, AndersCrnalic, Sead
Av organisasjonen
I samme tidsskrift
Acta Orthopaedica

Søk utenfor DiVA

GoogleGoogle Scholar
Totalt: 71 nedlastinger
Antall nedlastinger er summen av alle nedlastinger av alle fulltekster. Det kan for eksempel være tidligere versjoner som er ikke lenger tilgjengelige

doi
pubmed
urn-nbn

Altmetric

doi
pubmed
urn-nbn
Totalt: 567 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf