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Time trends and exposure determinants of lead and cadmium in the adult population of northern Sweden 1990-2014
Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Näringsforskning. (Arcum)
Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Yrkes- och miljömedicin.
Umeå universitet, Medicinska fakulteten, Enheten för biobanksforskning. Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Yrkes- och miljömedicin. (Arcum)
2017 (Engelska)Ingår i: Environmental Research, ISSN 0013-9351, E-ISSN 1096-0953, Vol. 159, s. 111-117Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

INTRODUCTION: This study follows cadmium and lead concentrations in blood in the adult population in northern Sweden over 24 years.

MATERIAL AND METHODS: Concentrations of lead and cadmium were measured in single whole blood samples (B-Pb and B-Cd) from 619 men and 926 women participating in the Northern Sweden WHO MONICA Study on one occasion 1990-2014. Associations with smoking and dietary factors were investigated. Consumption of moose meat was asked for in 2014.

RESULTS: In the adult population in northern Sweden, the median B-Pb in 2014 was 11.0µg/L in young (25-35 years) men and 9.69µg/L in young women. In an older age-group (50-60 years), the median B-Pb was 15.1µg/L in men and 13.1µg/L in women. B-Pb decreased from 1990 to 2009, after which time no further decrease was observed. B-Pb was higher in smokers than in non-smokers. In never-smokers, positive associations were found between B-Pb and consumption of wine and brewed coffee (women only) in 2004-2014. Higher B-Pb with consumption of moose meat was demonstrated in men, but not in women. B-Cd was essentially stable over the whole period, but an increase in B-Cd, of 3% per year, was detected in never-smoking women between 2009 and 2014. In 2014, median B-Cd in never-smokers in the four groups was; 0.11µg/L in younger men, 0.15µg/L in younger women, 0.14µg/L in older men, and 0.21µg/L in older women. B-Cd was higher in smokers than in non-smokers. The only positive association between B-Cd and food items in 2004-2014 was with consumption of brewed coffee (men only).

CONCLUSIONS: The lack of a decrease in B-Cd from 1990 to 2014 and the absence of a further decrease in B-Pb after 2009 are unsatisfactory considering the health risks these metals pose in the general population at current concentrations.

Ort, förlag, år, upplaga, sidor
San Diego: Academic Press, 2017. Vol. 159, s. 111-117
Nyckelord [en]
Cadmium, Human biomonitoring, Lead
Nationell ämneskategori
Arbetsmedicin och miljömedicin Miljövetenskap
Identifikatorer
URN: urn:nbn:se:umu:diva-139505DOI: 10.1016/j.envres.2017.07.029ISI: 000413280500013PubMedID: 28787621OAI: oai:DiVA.org:umu-139505DiVA, id: diva2:1141516
Tillgänglig från: 2017-09-15 Skapad: 2017-09-15 Senast uppdaterad: 2018-06-09Bibliografiskt granskad

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Wennberg, MariaNilsson Sommar, JohanBergdahl, Ingvar A.

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