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DNA damage-induced immune response: Micronuclei provide key platform
Umeå University, Faculty of Medicine, Department of Molecular Biology (Faculty of Medicine).
2017 (English)In: Journal of Cell Biology, ISSN 0021-9525, E-ISSN 1540-8140, Vol. 216, no 10, p. 2999-3001Article in journal, Editorial material (Other academic) Published
Abstract [en]

DNA damage-induced activation of the cytoplasmic DNA sensor cGAS influences the outcome of infections, autoinflammation, and cancer. Recent studies by Harding et al. (2017. Nature. http://dx.doi.org/10.1038/nature23470), Mackenzie et al. (2017. Nature. http://dx.doi.org/10.1038/nature23449), and Bartsch et al. (2017. Human Molecular Genetics. https://doi.org/10.1093/hmg/ddx283) demonstrate a role for micronuclei formation in DNA damage-induced immune activation.

Place, publisher, year, edition, pages
ROCKEFELLER UNIV PRESS , 2017. Vol. 216, no 10, p. 2999-3001
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Cell Biology
Identifiers
URN: urn:nbn:se:umu:diva-140887DOI: 10.1083/jcb.201708069ISI: 000411962700004PubMedID: 28860276OAI: oai:DiVA.org:umu-140887DiVA, id: diva2:1158701
Available from: 2017-11-21 Created: 2017-11-21 Last updated: 2018-06-09Bibliographically approved

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Gekara, Nelson O.

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