umu.sePublikationer
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus: a retrospective study
Visa övriga samt affilieringar
2019 (Engelska)Ingår i: Epidemiology and Infection, ISSN 0950-2688, E-ISSN 1469-4409, Vol. 147, artikel-id UNSP e35Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

The Middle East respiratory syndrome coronavirus (MERS-CoV) is a life-threatening respiratory disease with a high case fatality rate; however, its risk factors remain unclear. We aimed to explore the influence of demographic factors, clinical manifestations and underlying comorbidities on mortality in MERS-CoV patients. Retrospective chart reviews were performed to identify all laboratory-confirmed cases of MERS-COV infection in Saudi Arabia that were reported to the Ministry of Health of Saudi Arabia between 23 April 2014 and 7 June 2016. Statistical analyses were conducted to assess the effect of sex, age, clinical presentation and comorbidities on mortality from MERS-CoV. A total of 281 confirmed MERS-CoV cases were identified: 167 (59.4%) patients were male and 55 (20%) died. Mortality predominantly occurred among Saudi nationals and older patients and was significantly associated with respiratory failure and shortness of breath. Of the 281 confirmed cases, 160 (56.9%) involved comorbidities, wherein diabetes mellitus, hypertension, ischemic heart disease, congestive heart failure, end-stage renal disease and chronic kidney disease were significantly associated with mortality from MERS-CoV and two or three comorbidities significantly affected the fatality rates from MERS-CoV. The findings of this study show that old age and the existence of underlying comorbidities significantly increase mortality from MERS-CoV.

Ort, förlag, år, upplaga, sidor
Cambridge University Press, 2019. Vol. 147, artikel-id UNSP e35
Nyckelord [en]
Comorbidities, middle east respiratory syndrome coronavirus, mortality
Nationell ämneskategori
Infektionsmedicin
Identifikatorer
URN: urn:nbn:se:umu:diva-155975DOI: 10.1017/S0950268818002923ISI: 000455339100034PubMedID: 30394248OAI: oai:DiVA.org:umu-155975DiVA, id: diva2:1286691
Tillgänglig från: 2019-02-07 Skapad: 2019-02-07 Senast uppdaterad: 2019-02-07Bibliografiskt granskad

Open Access i DiVA

fulltext(191 kB)52 nedladdningar
Filinformation
Filnamn FULLTEXT01.pdfFilstorlek 191 kBChecksumma SHA-512
a55561686b0bbf9345442932fea413b7020ba2ffd22af583fd177caf81e1bde1becd82d582a9828866470ce6b8c9d83d444264fec1e36f92889830e661369c90
Typ fulltextMimetyp application/pdf

Övriga länkar

Förlagets fulltextPubMed

Personposter BETA

Mohamed, Nahla

Sök vidare i DiVA

Av författaren/redaktören
Mohamed, Nahla
Av organisationen
Virologi
I samma tidskrift
Epidemiology and Infection
Infektionsmedicin

Sök vidare utanför DiVA

GoogleGoogle Scholar
Totalt: 52 nedladdningar
Antalet nedladdningar är summan av nedladdningar för alla fulltexter. Det kan inkludera t.ex tidigare versioner som nu inte längre är tillgängliga.

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 379 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf