umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Compromised left atrial function and increased size predict raised cavity pressure: a systematic review and meta-analysis
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine. Universi College, Pristina, Kosovo, Albania; Clinic of Cardiology, University Clinical Centre of Kosovo, Pristina, Kosovo, Albania.ORCID iD: 0000-0002-8996-4257
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine. Universi College, Pristina, Kosovo, Albania.
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Clinical Physiology.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine. Molecular and Clinic Research Institute, St George University, and7Brunel University, London, UK.
2019 (English)In: Clinical Physiology and Functional Imaging, ISSN 1475-0961, E-ISSN 1475-097X, Vol. 39, no 5, p. 297-307Article, review/survey (Refereed) Published
Abstract [en]

Aim: This meta-analysis assesses left atrial (LA) cavity and myocardial function measurements that predict pulmonary capillary wedge pressure (PCWP). Methods: PubMed-MEDLINE, EMBASE, Scopus, Google Scholar and the Cochrane Central Registry were searched up to December 2018 for studies on the relationship of LA diameter, LA indexed volume (LAVI max, LAVI min), peak atrial longitudinal (PALS), peak atrial contraction (PACS) strain and total emptying fraction (LAEF) with PCWP. Eighteen studies with 1343 patients were included. sensitivity and specificity (with 95% CI) for evaluation of diagnostic accuracy and the best cut-off values for different LA indices in predicting raised PCWP were estimated using summary receiver operating characteristic analysis. Results: The pooled analysis showed association between PCWP and LA diameter: Cohen's d = 0 center dot 87, LAVI max: d = 0 center dot 92 and LAVI min: d = 1 center dot 0 (P<0 center dot 001 for all). A stronger correlation was found between PCWP and PALS: d = 1 center dot 26, and PACS: d = 1 center dot 62, total EF d = 1 center dot 22 (P<0 center dot 0001 for all). PALS <= 19% had a summary sensitivity of 80% (65-90) and summary specificity of 77% (52-92), positive likelihood ratio (LR+) 3 center dot 74, negative likelihood ratio (LR-) DOR > 15 center dot 1 whereas LAVI >= 34 ml m(-2) had summary sensitivity of 75% (55-89) and summary specificity 77% (57-90), with LR+ >3, LR- 0 center dot 32 and DOR >10 center dot 1. Conclusions: Compromised LA myocardial function and increased size predict raised cavity pressure. These results should assist in optimum follow-up of patients with fluctuating LA pressure.

Place, publisher, year, edition, pages
John Wiley & Sons, 2019. Vol. 39, no 5, p. 297-307
Keywords [en]
left atrial, left atrial function, left atrial size, left atrial strain, pulmonary capillary wedge pressure
National Category
Physiology
Identifiers
URN: urn:nbn:se:umu:diva-162835DOI: 10.1111/cpf.12587ISI: 000479117100001PubMedID: 31136072OAI: oai:DiVA.org:umu-162835DiVA, id: diva2:1351113
Available from: 2019-09-13 Created: 2019-09-13 Last updated: 2019-09-13Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMed

Authority records BETA

Bytyçi, IbadeteBajraktari, GaniLindqvist, PerHenein, Michael Y.

Search in DiVA

By author/editor
Bytyçi, IbadeteBajraktari, GaniLindqvist, PerHenein, Michael Y.
By organisation
Department of Public Health and Clinical MedicineClinical Physiology
In the same journal
Clinical Physiology and Functional Imaging
Physiology

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 25 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf