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Cubic phases in biosensing systems
Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Kemiska institutionen.
Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Kemiska institutionen. Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Centrum för medicinsk teknik och fysik (CMTF).
2008 (engelsk)Inngår i: Analytical and Bioanalytical Chemistry, ISSN 1618-2642, E-ISSN 1618-2650, Vol. 391, nr 5, s. 1569-1578Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Incorporation of membrane proteins with retained activity in artificial membranes for use in membrane-based sensors has attracted scientists for decades. This review briefly summarises general concepts on relevant cubic phases with and without incorporated proteins and provides some insight into the development of biosensors where bicontinuous cubic phases are used for incorporation of an enzyme. Some new data on impedance characterisation of a supported cubic phase are also shown. An efficient membrane-based electrochemical biosensor requires that the analyte has free access to the immobilised membrane protein and that regeneration of the catalysing enzyme is fast. Long-term stability of the system is also necessary for the biosensor to find applications outside the research laboratory. These basic concepts are discussed in the review along with presentation of those biosensing systems based on cubic phases that are reported in the literature.

sted, utgiver, år, opplag, sider
Springer, 2008. Vol. 391, nr 5, s. 1569-1578
Emneord [en]
Biosensors, Cubic phase, Membrane-based sensors
HSV kategori
Identifikatorer
URN: urn:nbn:se:umu:diva-9957DOI: 10.1007/s00216-008-2149-yISI: 000256908200010PubMedID: 18488208OAI: oai:DiVA.org:umu-9957DiVA, id: diva2:149628
Tilgjengelig fra: 2008-06-24 Laget: 2008-06-24 Sist oppdatert: 2020-01-23bibliografisk kontrollert

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