People with disabilities make up the largest minority group in the world (15% or 1 billion). Despite advocacy work and political advances in disability rights such as the UN Convention on the Rights of Persons with Disabilities, they are still marginalized in society and disability is often considered solely a medical condition associated with personal tragedy and exclusion. Since 2016, the European Research Council has funded the DISLIFE project’s proposal to research ‘liveable disabilities’ in Sweden from the 1800s until today. In this chapter, we present the project and its results on how societal circumstances have shaped the opportunities and lives of people with disabilities across time. We discuss the project’s use of the life course concept and from ableist perspectives and propose avenues for future research. Since the project results indicate that there have been little progress over time concerning the life opportunities of people with disabilities, a paramount work is ahead to which research aware of ableism can contribute.