Umeå University's logo

umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Association of depressive disorders and dementia with mortality among older people with hip fracture
Umeå University, Faculty of Medicine, Department of Nursing.
Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Geriatric Medicine.
Umeå University, Faculty of Medicine, Department of Surgical and Perioperative Sciences, Orthopaedics.ORCID iD: 0000-0002-5469-2730
Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Section of Physiotherapy.ORCID iD: 0000-0001-5859-4284
Show others and affiliations
2023 (English)In: BMC Geriatrics, E-ISSN 1471-2318, Vol. 23, no 1, article id 135Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Hip fracture (HF) is a significant cause of mortality among older people. Almost half of the patients with HF have dementia, which increases the mortality risk further. Cognitive impairment is associated with depressive disorders (DDs) and both dementia and DDs are independent risk factors for poor outcome after HF. However, most studies that evaluate mortality risk after HF separate these conditions.

AIMS: To investigate whether dementia with depressive disorders (DDwD) affects the mortality risk at 12, 24, and 36 months after HF among older people.

METHODS: Patients with acute HF (n = 404) were included in this retrospective analysis of two randomized controlled trials performed in orthopedic and geriatric departments. Depressive symptoms were assessed using the Geriatric Depression Scale and cognitive function was assessed using the Mini-Mental State Examination. A consultant geriatrician made final depressive disorder and dementia diagnoses using the Diagnostic and Statistical Manual of Mental Disorders criteria, with support from assessments and medical records. The 12-, 24- and 36-month mortality after HF was analyzed using logistic regression models adjusted for covariates.

RESULTS: In analyses adjusted for age, sex, comorbidity, pre-fracture walking ability, and fracture type, patients with DDwD had increased mortality risks at 12 [odds ratio (OR) 4.67, 95% confidence interval (CI) 1.75-12.51], 24 (OR 3.61, 95% CI 1.71-7.60), and 36 (OR 4.53, 95% CI 2.24-9.14) months. Similar results were obtained for patients with dementia, but not depressive disorders, alone.

CONCLUSION: DDwD is an important risk factor for increased mortality at 12, 24, and 36 months after HF among older people. Routinely assessments after HF for cognitive- and depressive disorders could identify patients at risk for increased mortality, and enable early interventions.

TRIAL REGISTRATION: RCT2: International Standard Randomized Controlled Trial Number Register, trial registration number: ISRCTN15738119.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2023. Vol. 23, no 1, article id 135
Keywords [en]
Dementia, Depressive disorders, Hip fracture, Mortality, Older people
National Category
Orthopaedics Geriatrics
Identifiers
URN: urn:nbn:se:umu:diva-205678DOI: 10.1186/s12877-023-03862-wISI: 000945613200001PubMedID: 36890449Scopus ID: 2-s2.0-85149626612OAI: oai:DiVA.org:umu-205678DiVA, id: diva2:1743099
Funder
Vårdal FoundationVisare NorrThe Kempe FoundationsUmeå UniversityRegion VästerbottenSwedish Research Council, K2005‐27VX‐15357‐01AAvailable from: 2023-03-14 Created: 2023-03-14 Last updated: 2024-07-04Bibliographically approved

Open Access in DiVA

fulltext(791 kB)111 downloads
File information
File name FULLTEXT01.pdfFile size 791 kBChecksum SHA-512
622b49539fb11add2cfe819222c4c210e81dceac8b1b20f10c811117b7275b40d319efcfe01f3800d52665ecaf50f758e8fe080597fefc438b8e4a0900c375f5
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMedScopus

Authority records

Olofsson, ErikaGustafson, YngveMukka, SebastianTengman, EvaLindgren, LenitaOlofsson, Birgitta

Search in DiVA

By author/editor
Olofsson, ErikaGustafson, YngveMukka, SebastianTengman, EvaLindgren, LenitaOlofsson, Birgitta
By organisation
Department of NursingGeriatric MedicineOrthopaedicsSection of Physiotherapy
In the same journal
BMC Geriatrics
OrthopaedicsGeriatrics

Search outside of DiVA

GoogleGoogle Scholar
Total: 111 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 344 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf