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Energy-efficient building retrofitting plays a crucial role in reducing energy consumption and carbon emissions within the building sector. Energy-efficient retrofitting brings about changes in the built environment and it could influence the occupant behaviors. Additionally, occupant behaviors, in turn, alter the indoor environment, thereby affecting the comfort performance of the building after retrofitting. To explore this intricate relation between occupant behaviors and comfort performances of energy-efficient measures, this paper employs a data-driven approach to compile a comprehensive dataset encompassing occupant behaviors, energy-efficient measures, and associated indoor comfort of an office building in Umeå University, Sweden. Multiple binary logistic regression is applied to quantify the relationship between occupant behaviors and comfort performances of energy-efficient measures. The findings of this study hold significant value, providing guidance for occupants in adapting to energy-efficient measures while also informing future retrofitting implementation.