Efficient, mild and completely regioselective synthesis of substituted pyridinesVisa övriga samt affilieringar
2010 (Engelska)Ingår i: Chemical Communications, ISSN 1359-7345, E-ISSN 1364-548X, Vol. 46, nr 19, s. 3384-3386Artikel i tidskrift (Refereegranskat) Published
Abstract [en]
Addition of Grignard reagents to pyridine N-oxides in THF at low temperature (-78 to -20 °C) and treatment with TFAA provides an efficient general procedure for synthesis of substituted pyridines. The method is compatible with a range of functional groups such as esters, halogens and nitriles.
Ort, förlag, år, upplaga, sidor
RSC Publishing, 2010. Vol. 46, nr 19, s. 3384-3386
Nyckelord [en]
Molecular Structure, Organometallic Compounds, chemistry, Pyridines, chemical synthesis, chemistry, Stereoisomerism, Temperature
Nationell ämneskategori
Kemi
Identifikatorer
URN: urn:nbn:se:umu:diva-32684DOI: 10.1039/c000748jISI: 000277318000047OAI: oai:DiVA.org:umu-32684DiVA, id: diva2:305100
2010-03-222010-03-222018-06-08Bibliografiskt granskad