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Association genetics of complex traits in plants
Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Institutionen för ekologi, miljö och geovetenskap.
Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Institutionen för fysiologisk botanik. Umeå universitet, Teknisk-naturvetenskapliga fakulteten, Umeå Plant Science Centre (UPSC).ORCID-id: 0000-0001-6031-005X
2011 (engelsk)Inngår i: New Phytologist, ISSN 0028-646X, E-ISSN 1469-8137, Vol. 189, nr 4, s. 909-922Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Association mapping is rapidly becoming the main method for dissecting the genetic architecture of complex traits in plants. Currently most association mapping studies in plants are preformed using sets of genes selected to be putative candidates for the trait of interest, but rapid developments in genomics will allow for genome-wide mapping in virtually any plant species in the near future. As the costs for genotyping are decreasing, the focus has shifted towards phenotyping. In plants, clonal replication and/or inbred lines allows for replicated phenotyping under many different environmental conditions. Reduced sequencing costs will increase the number of studies that use RNA sequencing data to perform expression quantitative trait locus (eQTL) mapping, which will increase our knowledge of how gene expression variation contributes to phenotypic variation. Current population sizes used in association mapping studies are modest in size and need to be greatly increased if mutations explaining less than a few per cent of the phenotypic variation are to be detected. Association mapping has started to yield insights into the genetic architecture of complex traits in plants, and future studies with greater genome coverage will help to elucidate how plants have managed to adapt to a wide variety of environmental conditions.

sted, utgiver, år, opplag, sider
Oxford: Blackwell Scientific Publications Ltd , 2011. Vol. 189, nr 4, s. 909-922
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URN: urn:nbn:se:umu:diva-40052DOI: 10.1111/j.1469-8137.2010.03593.xPubMedID: 21182529OAI: oai:DiVA.org:umu-40052DiVA, id: diva2:397739
Tilgjengelig fra: 2011-02-15 Laget: 2011-02-15 Sist oppdatert: 2018-06-08bibliografisk kontrollert

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