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Psychiatric treatment in men with prostate cancer: results from a Nation-wide, population-based cohort study from PCBaSe Sweden.
Vise andre og tillknytning
2011 (engelsk)Inngår i: European Journal of Cancer, ISSN 0959-8049, E-ISSN 1879-0852, Vol. 47, nr 14, s. 2195-201Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Aim: To explore whether the self-reported psychological distress among men with prostate cancer was to the extent that it required psychiatric treatment.

Methods: PCBaSe Sweden, a merged database based on the National Prostate Cancer Register including 97% of allprostate cancers registered as well as age-matched controls. We calculated relative risks and 95% confidence intervals to compare risks of psychiatric treatment due to depression, anxiety, and post-traumatic stress disordercontrolling for age and socio-economic factors. We used odds ratios to compare use or no use of antidepressants.

Findings: In total 72,613 men with prostate cancer and 217,839 men without prostate cancer were included for analyses. Psychiatric hospitalisation due to depression, anxiety and post-traumatic stress disorder were significantly increased (RR 1.29, (95% CI 1.14–1.45), RR 1.42 (95% CI 1.12–1.80) and RR 1.61 (95% CI 1.16–2.24), respectively). However, hospitalisations due to anxiety were only increased in men with more advanced tumours RR 2.28 (95% CI 1.45–3.57). The use of antidepressants was increased for all men with prostate cancer RR 1.65 (95% CI 1.54–1.77) and treatment strategies RR 1.93 (95% CI 1.75–2.13).

Interpretation: Men diagnosed with prostate cancer had increased risk of psychiatric treatment for depression, post-traumatic stress disorder and use of antidepressants regardless of risk group and treatment strategy compared to age-matched controls, whilst more advanced prostate cancer was associated with severe anxiety disorders.

sted, utgiver, år, opplag, sider
Oxford: Pergamon , 2011. Vol. 47, nr 14, s. 2195-201
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Identifikatorer
URN: urn:nbn:se:umu:diva-48431DOI: 10.1016/j.ejca.2011.04.022PubMedID: 21612913OAI: oai:DiVA.org:umu-48431DiVA, id: diva2:450309
Tilgjengelig fra: 2011-10-20 Laget: 2011-10-20 Sist oppdatert: 2018-06-08bibliografisk kontrollert

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