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Plasma phospholipid long-chain n-3 polyunsaturated fatty acids and body weight change
Vise andre og tillknytning
2011 (engelsk)Inngår i: Obesity facts, ISSN 1662-4033, Vol. 4, nr 4, s. 312-318Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

OBJECTIVE: We investigated the association between the proportion of long-chain n-3 polyunsaturated fatty acids (PUFA) in plasma phospholipids from blood samples drawn at enrollment and subsequent change in body weight. Sex, age, and BMI were considered as potential effect modifiers.

METHOD: A total of 1,998 women and men participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) were followed for a median of 4.9 years. The associations between the proportion of plasma phospholipid long-chain n-3 PUFA and change in weight were investigated using mixed-effect linear regression.

RESULTS: The proportion of long-chain n-3 PUFA was not associated with change in weight. Among all participants, the 1-year weight change was -0.7 g per 1% point higher long-chain n-3 PUFA level (95% confidence interval: -20.7 to 19.3). The results when stratified by sex, age, or BMI groups were not systematically different.

CONCLUSION: The results of this study suggest that the proportion of long-chain n-3 PUFA in plasma phospholipids is not associated with subsequent change in body weight within the range of exposure in the general population.

sted, utgiver, år, opplag, sider
2011. Vol. 4, nr 4, s. 312-318
Emneord [en]
Body weight, Cohort study, n-3 fatty acids, Omega-3 fatty acids, Weight change
HSV kategori
Identifikatorer
URN: urn:nbn:se:umu:diva-51193DOI: 10.1159/000330710ISI: 000294763300009PubMedID: 21921655OAI: oai:DiVA.org:umu-51193DiVA, id: diva2:476792
Tilgjengelig fra: 2012-01-12 Laget: 2012-01-12 Sist oppdatert: 2018-06-08bibliografisk kontrollert

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