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Prevalence of risk factors for cardiovascular disease stratified by body mass index categories in patients with wheelchair-dependent paraplegia after spinal cord injury
Umeå universitet, Medicinska fakulteten, Institutionen för samhällsmedicin och rehabilitering, Rehabiliteringsmedicin.
Umeå universitet, Medicinska fakulteten, Institutionen för samhällsmedicin och rehabilitering, Rehabiliteringsmedicin.
Umeå universitet, Medicinska fakulteten, Institutionen för klinisk vetenskap, Professionell utveckling. Umeå universitet, Medicinska fakulteten, Institutionen för samhällsmedicin och rehabilitering, Rehabiliteringsmedicin.
2012 (engelsk)Inngår i: Journal of Rehabilitation Medicine, ISSN 1650-1977, E-ISSN 1651-2081, Vol. 44, nr 5, s. 440-443Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Objective: To assess risk factors for cardiovascular disease at different body mass index values in persons with wheelchair-dependent paraplegia after spinal cord injuries. Design: Cross-sectional study. Subjects: A total of 135 individuals, age range 18-79 years, with chronic (>= 1 year) post-traumatic paraplegia. Methods: Body mass index was stratified into 6 categorical groups. Cardiovascular disease risk factors for hypertension, diabetes mellitus and a serum lipid profile were analysed and reported by body mass index category. Results: More than 80% of the examined participants had at least one cardiovascular disease risk factor irrespective of body mass index level. Hypertension was highly prevalent, especially in men. Dyslipidaemia was common at all body mass index categories in both men and women. Conclusion: Higher body mass index values tended to associate with more hypertension and diabetes mellitus, whereas dyslipidaemia was prevalent across all body mass index categories. Studies that intervene to reduce weight and or percentage body fat should be performed to determine the effect on reducing modifiable cardiovascular disease risk factors.

sted, utgiver, år, opplag, sider
2012. Vol. 44, nr 5, s. 440-443
HSV kategori
Identifikatorer
URN: urn:nbn:se:umu:diva-57172DOI: 10.2340/16501977-0964ISI: 000305112300008OAI: oai:DiVA.org:umu-57172DiVA, id: diva2:540245
Tilgjengelig fra: 2012-07-09 Laget: 2012-07-09 Sist oppdatert: 2018-06-08bibliografisk kontrollert
Inngår i avhandling
1. Spinal cord injuries in Sweden: studies on clinical follow-ups
Åpne denne publikasjonen i ny fane eller vindu >>Spinal cord injuries in Sweden: studies on clinical follow-ups
2016 (engelsk)Doktoravhandling, med artikler (Annet vitenskapelig)
Abstract [en]

A spinal cord injury is a serious medical condition, often caused by a physical trauma. An injury to the spinal cord affects the neurotransmission between the brain and spinal cord segments below the level of injury. The SCI causes a loss of motor function, sensory function and autonomic regulation of the body, temporary or permanent. Significantly improved acute care, primary comprehensive rehabilitation and life-long structured follow-up has led to persons with spinal cord injury (SCI) living longer than ever before. However, increased long-time survival has allowed secondary conditions to emerge, like diabetes mellitus and where cardiovascular disease (CVD) now is the most common cause of death among SCI patients. Other possible CVD-related comorbidities in this patient group have been reported to be pain and mood disturbances. There is still lack of, and need for more knowledge in the field of CVD-related screening and prevention after SCI.

The overall aim of this thesis was to contribute to a scientific ground regarding the need for CVD-related screening and prevention after SCI.

In Paper I and Paper II, patients with wheelchair-dependent post-traumatic SCI (paraplegia) were assessed. The results in paper I showed that 80% of the examined patients had at least one cardiovascular disease risk marker irrespective of body mass index (BMI). Dyslipidemia was common for both men and women at all BMI categories. The study also showed a high prevalence of hypertension, especially in men. Paper II showed a low frequency of self-reported physical activity, where only one out of 5 persons reported undertaking physical activity >30 min/day. The physically active had lower diastolic blood pressure but no significant difference in blood lipids.

In paper III and IV, patients with SCI (tetraplegia and paraplegia) participated in the studies. Eighty-one percent of the patients had dyslipidemia, where also a majority of the patients with normal abdominal clinical measures had dyslipidemia. Self-reported physical activity >30min/day was reported by one third of the patients. No differences were found between physically active and not physically active patients when it came to blood glucose, serum lipid values and clinical measures (paper III). Pain was common in the patient group, however, most often on a mild to moderate level. Anxiety and depression was less common than reported in other studies (paper IV).

sted, utgiver, år, opplag, sider
Umeå: Umeå universitet, 2016. s. 73
Serie
Umeå University medical dissertations, ISSN 0346-6612 ; 1824
Emneord
Tetraplegia, paraplegia, cardiovascular disease, prevention, anthropometry, physical activity
HSV kategori
Forskningsprogram
rehabiliteringsmedicin
Identifikatorer
urn:nbn:se:umu:diva-125202 (URN)978-91-7601-526-1 (ISBN)
Disputas
2016-09-30, Aulan, Vårdvetarhuset, Umeå, 09:00 (svensk)
Opponent
Veileder
Tilgjengelig fra: 2016-09-09 Laget: 2016-09-08 Sist oppdatert: 2018-06-07bibliografisk kontrollert

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