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A prospective cohort study investigating an exposure-response relationship among vibration-exposed male workers with numbness of the hands
Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Yrkes- och miljömedicin.
Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Yrkes- och miljömedicin.
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2014 (Engelska)Ingår i: Scandinavian Journal of Work, Environment and Health, ISSN 0355-3140, E-ISSN 1795-990X, Vol. 40, nr 2, s. 203-209Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

OBJECTIVE: The aim of this study was to investigate the exposure-response relationship of hand-arm vibration exposure to neurological symptoms (numbness) of the hand in a cohort of vibration-exposed workers.

METHODS: The baseline cohort comprised 241 office and manual workers with or without exposure to hand-arm vibration. Numbness (the symptom or event) in the hand was assessed for all subjects at baseline and follow-ups after 5, 10, and 16 years. The workers were stratified into quartiles with no exposure in the first quartile and increasing intensity of exposure in quartiles 2-4 (groups 1-3). Data analysis was performed using survival analysis (time to event). Information on cumulative exposure and years of exposure to event was collected via questionnaires. Measurements were performed in accordance with the International Organization for Standardization (ISO) 5349-1.

RESULTS: The hazard ratio (HR) of risk of event (numbness) differed statistically significantly between the non-exposed group (group 0) and the two higher exposure groups (groups 2 and 3). There was also a significant ratio difference between the lowest exposure group (group 1) and the two higher groups. The ratio for group 1 was 1.77 [95% confidence interval (95% CI) 0.96-3.26] compared with 3.78 (95% CI 2.15-6.62) and 5.31 (95% CI 3.06-9.20) for groups 2 and 3, respectively.

CONCLUSION: The results suggest a dose-response relationship between vibration exposure and numbness of the hands. This underlines the importance of keeping vibration levels low to prevent neurological injury to the hands.

Ort, förlag, år, upplaga, sidor
Tyoterveyslaitos , 2014. Vol. 40, nr 2, s. 203-209
Nyckelord [en]
carpal tunnel syndrome, hand-arm vibration, HAV, sensorineural symptom, survival analysis, work performance
Nationell ämneskategori
Arbetsmedicin och miljömedicin
Identifikatorer
URN: urn:nbn:se:umu:diva-83950DOI: 10.5271/sjweh.3386ISI: 000333321500010PubMedID: 24067946OAI: oai:DiVA.org:umu-83950DiVA, id: diva2:678070
Tillgänglig från: 2013-12-11 Skapad: 2013-12-11 Senast uppdaterad: 2018-06-08Bibliografiskt granskad

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Burström, LageLundström, RonnieNilsson, Tohr

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