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Adequate vitamin D levels in a Swedish population living above latitude 63°N: The 2009 Northern Sweden MONICA study
Umeå universitet, Medicinska fakulteten, Institutionen för samhällsmedicin och rehabilitering, Geriatrik.
Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Epidemiologi och global hälsa. (Arcum)ORCID-id: 0000-0003-2475-7131
Umeå universitet, Medicinska fakulteten, Institutionen för farmakologi och klinisk neurovetenskap, Farmakologi.
Umeå universitet, Medicinska fakulteten, Institutionen för folkhälsa och klinisk medicin, Medicin. Umeå universitet, Arktiskt centrum vid Umeå universitet (Arcum). (Sunderby Research U ; Arcum)
2015 (engelsk)Inngår i: International Journal of Circumpolar Health, ISSN 1239-9736, E-ISSN 2242-3982, Vol. 74, nr 1, artikkel-id 27963Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

BACKGROUND: Even though vitamin D is mainly produced by exposure to sunlight, little is known regarding vitamin D levels in populations living in sub-Arctic areas with little or no daylight during winter.

OBJECTIVE: We describe distributions of vitamin D3 and the prevalence of adequate levels in a population living above 63°N.

DESIGN: We sampled 1,622 randomly selected subjects, aged 25-74 years, between January and May, 2009, as part of the Northern Sweden MONICA study (69.2% participation rate). By using HPLC, 25(OH) vitamin D3 was analysed. Levels used for definitions were deficient, D3<25 nmol/l (<10 ng/ml); insufficient, D3 25-49.9 nmol/l (10-20 ng/ml); and adequate, D3≥50 nmol/l (20 ng/ml).

RESULTS: Mean (median) level of vitamin D3 was 65.2 (63.6) nmol/l in men and 71.0 (67.7) nmol/l in women. Adequate levels were found in 79.2%, more often in women (82.7%) than in men (75.6%). Only 0.7% of the population were vitamin D3-deficient but 23.1% of men and 17.1% of women had insufficient levels. Levels of vitamin D3 increased with age and insufficient status was most common among those aged 25-34 years, 41.0% in men and 22.3% in women. If subjects using vitamin D-supplementation are excluded, the population level of D3 is 1-2 nmol/l lower than in the general population across sex- and age groups. There were no differences between the northern or the southern parts, between urban or rural living or according to educational attainment. Those subjects born outside of Sweden or Finland had lower levels.

CONCLUSION: The large majority living close to the Arctic Circle in Sweden have adequate D3 levels even during the second half of the dark winter. Subjects with D3 deficiency were uncommon but insufficient levels were often found among young men.

sted, utgiver, år, opplag, sider
CoAction Publishing, 2015. Vol. 74, nr 1, artikkel-id 27963
Emneord [en]
hydroxyvitamin D levels, vitamin D insufficiency/deficiency/status, population study, observational (cohort) design, age, gender
HSV kategori
Identifikatorer
URN: urn:nbn:se:umu:diva-103056DOI: 10.3402/ijch.v74.27963ISI: 000358042400001PubMedID: 28417824OAI: oai:DiVA.org:umu-103056DiVA, id: diva2:812322
Tilgjengelig fra: 2015-05-18 Laget: 2015-05-18 Sist oppdatert: 2018-06-07bibliografisk kontrollert

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Ramnemark, AnnaNorberg, MargaretaPettersson-Kymmer, UlrikaEliasson, Mats

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