Umeå University's logo

umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
The Obstructive Lung Disease in Northern Sweden (OLIN) longitudinal paediatric study I: the first 10 years
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine. The OLIN Studies, Department of Medicine, Sunderby Central Hospital of Norrbotten, Luleå, Sweden.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Pulmonary Medicine. The OLIN Studies, Department of Medicine, Sunderby Central Hospital of Norrbotten, Luleå, Sweden.
Show others and affiliations
2008 (English)In: Clinical Respiratory Journal, ISSN 1752-6981, E-ISSN 1752-699X, Vol. 2, no Suppl 1, p. 26-33Article in journal (Refereed) Published
Resource type
Text
Abstract [en]

Background: Prospective studies of asthma and allergic conditions based oil the general population are scare.

Aim: To summarize the methods and main results from a prospective study among school children.

Methods: In 1996, a cohort of 3525 children aged 7/8 years in Northern Sweden were invited to a questionnaire survey using an expanded ISAAC protocol, and 97% participated. The cohort has been followed up yearly with high participation rate. Skin prick tests were conducted 1996, 2000 and 2006/2007. Allergens in dust from homes and schools have been analyzed. Sub samples have participated in interviews, lung function tests, bronchial hyper reactivity test, and analyses of IgE and IgG antibodies in serum.

Results: The prevalence of asthma was 6% at age 7-8 years and increased by age. The incidence of physician-diagnosed asthma after the age of 7-8 years was around 1/100/year. The prevalence of positive skin prick test increased from 21% at age 7-8 to 30% at age 11-12 years. Remission of allergic sensitization was rare, while asthma remission was 5% yearly. The main risk factor for asthma and allergic sensitization increased in importance with increasing age. Allergic and non-allergic asthma had different risk factor pattern. Environmental risk factors decreased in impact after the age of 7. Avoidance of pets at home did not protect from asthma or allergic sensitization.

Conclusion: The study includes important sources of data for further longitudinal analyses that will contribute to the understanding of the development and the nature of asthma and allergic sensitization.

Place, publisher, year, edition, pages
Oxford: Blackwell Publishing, 2008. Vol. 2, no Suppl 1, p. 26-33
Keywords [en]
asthma, allergic sensitization, prevalence, incidence
National Category
Respiratory Medicine and Allergy
Identifiers
URN: urn:nbn:se:umu:diva-117482DOI: 10.1111/j.1752-699X.2008.00081.xISI: 000259610500004PubMedID: 20298347OAI: oai:DiVA.org:umu-117482DiVA, id: diva2:911583
Conference
Workshop on Respiratory Epidemiologic Research, AUG 18-21, 2007, Lofoten, NORWAY
Available from: 2016-03-14 Created: 2016-03-01 Last updated: 2018-06-07Bibliographically approved

Open Access in DiVA

No full text in DiVA

Other links

Publisher's full textPubMed

Authority records

Rönmark, EvaBjerg, Anders

Search in DiVA

By author/editor
Rönmark, EvaBjerg, Anders
By organisation
Occupational and Environmental MedicinePulmonary Medicine
In the same journal
Clinical Respiratory Journal
Respiratory Medicine and Allergy

Search outside of DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric score

doi
pubmed
urn-nbn
Total: 81 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf