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Comparison of joint status with ultrasound and physical examination in children with hemophilia A
Umeå University, Faculty of Medicine, Department of Community Medicine and Rehabilitation, Physiotherapy.
2016 (English)Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
Abstract [en]

Introduction: Hemophilia A is a bleeding disorder that can cause chronic artropathy, when not treated optimally. To detect early signs of hemophilic artropathy patients with moderate or severe hemophilia undergo yearly examinations by a physiotherapist defining the joint status by a scoring system, “HJHS”. A new ultrasound-based scoring system, HEAD-US, has been developed to evaluate joint disease progression and treatment results. The aim of this study is to evaluate if there is a correlation between HJHS 2.1 and HEAD-US in children with hemophilia A. Furthermore, to evaluate if there is a correlation between physical activity and hemophilic artropathy and finally to asses if there are any differences in artropathy between sub-groups within the study group.

Methods: A prospective study where all patients between ages 3 to 18 years with moderate or severe hemophilia followed at the Karolinska University Hospital 2015-2016 were asked to participate. Patients were asked to fill in a questionnaire regarding physical activity and joint bleeds and clinical data were retrospectively collected from the patients’ medical records. Joints were evaluated by the author according to HJHS and HEAD-US.

Results: There was a significant correlation between the total-, elbow-, knee- and ankle scores for HJHS and HEAD-US scores. There was a statistically significant correlation between annual bleeding rate and total scores for HJHS and HEAD-US. No statistically significant correlation was seen between the total score of HJHS or HEAD-US and the level of physical activity.

Conclusions: This study demonstrates that the total score and individual joint scores with HEAD-US correlate well with the current method HJHS 2.1 in children with hemophilia A. 

Place, publisher, year, edition, pages
2016. , p. 40
Keyword [en]
Hemofilia a, HJHS, HEAD-US, Pediatric, Hemofilic artropathy
National Category
Physiotherapy
Identifiers
URN: urn:nbn:se:umu:diva-126899OAI: oai:DiVA.org:umu-126899DiVA, id: diva2:1038807
External cooperation
Susanna Ranta, Karolinska Universitetssjukhuset, Solna
Educational program
Graduate Programme in Physiotherapy
Presentation
2016-09-26, A102, Vårdvetarhuset, Umeå universitet, Umeå, 13:00 (Swedish)
Supervisors
Examiners
Available from: 2016-12-28 Created: 2016-10-19 Last updated: 2016-12-28Bibliographically approved

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CiteExportLink to record
Permanent link

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Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
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  • nn-NO
  • nn-NB
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More languages
Output format
  • html
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  • asciidoc
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