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Pregnancy and Guillain-Barré syndrome: a nationwide register cohort study.
Division of Neurology, Department of Clinical Neuroscience and Family Medicine, Huddinge University Hospital, Huddinge, Sweden.
Division of Neurology, Department of Clinical Neuroscience and Family Medicine, Huddinge University Hospital, Huddinge, Sweden. Department of Applied Epidemiology, National Centre for Epidemiology, Carlos III Institute of Health, Madrid, Spain.
Department of Surgery, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden.
Division of Neurology, Department of Clinical Neuroscience and Family Medicine, Huddinge University Hospital, Huddinge, Sweden.
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1996 (English)In: Neuroepidemiology, ISSN 0251-5350, E-ISSN 1423-0208, Vol. 15, no 4, 192-200 p.Article in journal (Refereed) Published
Abstract [en]

In this study, we determined the relationship between Guillain-Barré syndrome (GBS) and pregnancy. By taking advantage of several nationwide registers and the availability of personal identification numbers, we calculated person-years for Swedish females aged 15-49 years in the following categories: (1) neither pregnant nor postpartum; (2) pregnant; (3) in the first month postpartum, or (4) in the first 3 months postpartum during 1973-1983. For these women, we determined the corresponding exposure status of hospital-registered GBS cases. Medical records were examined for GBS cases hospitalized during the 2-week period postpartum and 1-month period after the last menstruation. Poisson regression analysis yielded age-adjusted relative risks (RRs) of 0.86 (95% CI 0.40-1.84) for pregnant women, and 1.47 (0.54-3.99) and 2.21 (0.55-8.94) for females during the 3-month and the 30-day period after delivery. The risk for GBS seems to be lower during pregnancy and increases after delivery.

Place, publisher, year, edition, pages
1996. Vol. 15, no 4, 192-200 p.
Keyword [en]
Pregnancy, Guillain-Barré syndrome
National Category
Surgery
Identifiers
URN: urn:nbn:se:umu:diva-126906PubMedID: 8817501OAI: oai:DiVA.org:umu-126906DiVA: diva2:1038850
Available from: 2016-10-20 Created: 2016-10-20 Last updated: 2016-10-20

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