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One Year Survival in Nigerians with Peripartum Cardiomyopathy
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Cardiology. Department of Medicine, Aminu Kano Teaching Hospital, Bayero University, Kano, Nigeria.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Cardiology.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Cardiology.
2016 (English)In: Heart Views, ISSN 1995-705X, Vol. 17, no 2, 55-61 p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Peripartum cardiomyopathy (PPCM) is common in North-Western Nigeria. This study aimed to describe the 1-year survival and left ventricular reverse remodeling (LVRR) in a group of patients with PPCM from three referral hospitals in Kano, Nigeria.

METHODS: PPCM was defined according to recommendations of the Heart Failure (HF) Association of the European Society of Cardiology Working Group on PPCM. LVRR was defined as absolute increase in left ventricular ejection fraction (LVEF) by ≥10.0% and decrease in left ventricular (LV) end-diastolic dimension indexed to body surface area ≤33.0 mm/m(2), while recovered LV systolic function as LVEF ≥55%, at 12 months follow-up.

RESULTS: A total of 54 newly diagnosed PPCM patients with mean age of 26.6 ± 6.7 years, presented with classical features of predominantly left-sided HF and 33 of them qualified for follow-up. Of the 17 survivors at 12 months, 8 patients (47.1%) satisfied the criteria for LVRR, of whom 5 (29.4%) had recovered LV systolic function (LVEF ≥55%), but LVRR was not predicted by any variable in the regression models. The prevalence of normal LV diastolic function increased from 11.1% at baseline to 35.3% at 12 months (P = 0.02). At 1-year follow-up, 41.4% of patients had died (two-thirds of them within the first 6 months), but mortality was not predicted by any variable including LVRR.

CONCLUSIONS: In Kano, PPCM patients had modest LVRR but high mortality at 1-year. Further studies should be carried out to identify reasons for the high mortality and how to curb it.

Place, publisher, year, edition, pages
2016. Vol. 17, no 2, 55-61 p.
National Category
Cardiac and Cardiovascular Systems
Research subject
Cardiology
Identifiers
URN: urn:nbn:se:umu:diva-126950DOI: 10.4103/1995-705X.185114PubMedID: 27512533OAI: oai:DiVA.org:umu-126950DiVA: diva2:1039494
Available from: 2016-10-24 Created: 2016-10-24 Last updated: 2017-01-27Bibliographically approved

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CiteExportLink to record
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