Change search
ReferencesLink to record
Permanent link

Direct link
Only severe COPD is associated with being underweight: results from a population survey.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine.
Show others and affiliations
2016 (English)In: ERJ open research, E-ISSN 2312-0541, Vol. 2, no 3Article in journal (Refereed) Published
Abstract [en]

Low body mass index (BMI) and malnutrition in chronic obstructive pulmonary disease (COPD) are associated with a poor prognosis. The prevalence of underweight, as well as overweight, in severity grades of COPD is sparsely investigated in studies of the general population and the associated patterns of risk factors are not well established. The aim of the present study was to determine the association between severity grades of airflow limitation in COPD, and both underweight and obesity when corrected for possible confounding factors. The study is based on pooled data from the OLIN (Obstructive Lung Disease in Northern Sweden) studies. Complete records with lung function, BMI and structured interview data were available from 3942 subjects (50.7% women and 49.3% men). COPD and severity grading were defined using the Global Initiative for Chronic Obstructive Lung Disease criteria. In sensitivity analyses, the lower limit of normal was used. The prevalence of underweight was 7.3% in severe COPD (grades 3 and 4) versus 2.0% in those with normal spirometry. The prevalence of obesity increased from 9.7% in grade 1, to 16.3% in grade 2 and 20.0% in severe COPD, versus 17.7% in those with normal spirometry. In adjusted analysis, of the COPD severity grades, only severe COPD was associated with underweight (OR 3.24, 95% CI 1.0004-10.5), while the COPD severity grades tended to be inversely associated with overweight.

Place, publisher, year, edition, pages
Sheffield: European Respiratory Society , 2016. Vol. 2, no 3
National Category
Environmental Health and Occupational Health
URN: urn:nbn:se:umu:diva-128107DOI: 10.1183/23120541.00051-2015PubMedID: 27730201OAI: diva2:1049056
Available from: 2016-11-23 Created: 2016-11-23 Last updated: 2017-01-23Bibliographically approved

Open Access in DiVA

fulltext(704 kB)6 downloads
File information
File name FULLTEXT01.pdfFile size 704 kBChecksum SHA-512
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Backman, HelenaHedman, LinneaLindberg, AnneRönmark, Eva
By organisation
Occupational and Environmental MedicineMedicine
Environmental Health and Occupational Health

Search outside of DiVA

GoogleGoogle Scholar
Total: 6 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 3 hits
ReferencesLink to record
Permanent link

Direct link