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Diabetes mellitus, high BMI and low education level predict sudden cardiac death within 24 hours of incident myocardial infarction
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine. (Skellefteå Research Unit)
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine, Family Medicine.
Umeå University, Faculty of Medicine, Department of Public Health and Clinical Medicine. (Sunderby Research Unit)
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2016 (English)In: European Journal of Preventive Cardiology, ISSN 2047-4873, E-ISSN 2047-4881, Vol. 23, no 17, 1814-1820 p.Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: More than half of cardiovascular mortality occurs outside the hospital, mainly due to consistently low survival rates from out-of-hospital cardiac arrest.

METHODS: This is a prospective, nested, case-control study derived from the Västerbotten Intervention Programme and the World Health Organization's Multinational Monitoring of Trends and Determinants in Cardiovascular Disease study in northern Sweden (1986-2006). To determine predictors for sudden cardiac death risk factors for cardiovascular disease were compared between incident myocardial infarction with sudden cardiac death (n = 363) and survivors of incident myocardial infarction (n = 1998) using multivariate logistic regression analysis.

RESULTS: Diabetes had the strongest association with sudden cardiac death out of all evaluated risk factors (odds ratio (OR) 1.83, 95% confidence interval (CI) 1.30-2.59), followed by low education (OR 1.55, 95% CI 1.19-2.01), high body mass index (OR 1.05, 95% CI 1.02-1.08) and male sex (OR 1.42, 95% CI 1.001-2.01).

CONCLUSIONS: The pattern of risk factors for incident myocardial infarction is different among survivors and those who die within 24 hours. The risk factors that contribute the most to death within 24 hours are diabetes mellitus, high body mass index and low education level, and can be addressed at both the public health level and by general practitioners.

Place, publisher, year, edition, pages
2016. Vol. 23, no 17, 1814-1820 p.
Keyword [en]
Sudden cardiac death, epidemiology, myocardial infarction, risk factors, prevention, prognosis
National Category
Cardiac and Cardiovascular Systems
Identifiers
URN: urn:nbn:se:umu:diva-129017DOI: 10.1177/2047487316659574ISI: 000387017100003PubMedID: 27435083OAI: oai:DiVA.org:umu-129017DiVA: diva2:1058321
Available from: 2016-12-20 Created: 2016-12-20 Last updated: 2017-01-23Bibliographically approved

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Andersson, JonasWennberg, PatrikLundblad, DanJansson, Jan-Håkan
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