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ZNF217/ZFP217 Meets Chromatin and RNA
Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
2016 (English)In: TIBS -Trends in Biochemical Sciences. Regular ed., ISSN 0968-0004, E-ISSN 1362-4326, Vol. 41, no 12, p. 986-988Article in journal, Editorial material (Refereed) Published
Abstract [en]

The Kruppel-like transcription factor zinc finger protein (ZNF)217 (mouse homolog ZFP217) contributes to tumorigenesis by dysregulating gene expression programs. The newly discovered molecular function of ZFP217 in controlling N6-methyladenosine (m6A) deposition in embryonic stem cells (ESCs) sheds new light on the role of this transcription factor in tumor development.

Place, publisher, year, edition, pages
2016. Vol. 41, no 12, p. 986-988
Keywords [en]
ZNF217, cancer, stem cell, N6-methyladenosine, RNA methylation
National Category
Cell and Molecular Biology
Identifiers
URN: urn:nbn:se:umu:diva-129271DOI: 10.1016/j.tibs.2016.07.013ISI: 000389106400003PubMedID: 27519282OAI: oai:DiVA.org:umu-129271DiVA, id: diva2:1058977
Available from: 2016-12-22 Created: 2016-12-22 Last updated: 2018-06-09Bibliographically approved

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Aguiló, Francesca

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