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ZNF217/ZFP217 Meets Chromatin and RNA.
Umeå University, Faculty of Medicine, Department of Medical Biosciences. (Francesca Aguilo)
2016 (English)In: TIBS -Trends in Biochemical Sciences. Regular ed., ISSN 0968-0004, E-ISSN 1362-4326, Vol. 41, no 12Article in journal (Refereed) Published
Abstract [en]

The Kruppel-like transcription factor zinc finger protein (ZNF)217 (mouse homolog ZFP217) contributes to tumorigenesis by dysregulating gene expression programs. The newly discovered molecular function of ZFP217 in controlling N6-methyladenosine (m(6)A) deposition in embryonic stem cells (ESCs) sheds new light on the role of this transcription factor in tumor development.

Place, publisher, year, edition, pages
2016. Vol. 41, no 12
National Category
Cell and Molecular Biology
Identifiers
URN: urn:nbn:se:umu:diva-129271DOI: 10.1016/j.tibs.2016.07.013PubMedID: 27519282OAI: oai:DiVA.org:umu-129271DiVA: diva2:1058977
Available from: 2016-12-22 Created: 2016-12-22 Last updated: 2017-05-15

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