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Comment on: Early CSF and serum S 100B concentrations for outcome prediction in traumatic brain injury and subarachoid haemorrhage
Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience, Clinical Neuroscience. Department of Anaesthesiology and Intensive Care, Section for Neurosurgery, Faculty of Health and Medicine, University Hospital Orebro, SE 70185, Orebro, Sweden.
Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience, Clinical Neuroscience.
2016 (English)In: Clinical neurology and neurosurgery (Dutch-Flemish ed. Print), ISSN 0303-8467, E-ISSN 1872-6968, Vol. 150, 197-198 p.Article in journal, Letter (Refereed) Published
Abstract [en]

Background and methods

In the letter the authors discuss the findings in Kellerman and co-worker’s paper: Early CSF and Serum S 100B Concentrations for Outcome Prediction in Traumatic Brain Injury and Subarachoid Haemorrhage published in this journal. Among the findings reported in this paper is that an initial S 100B value of more than 0.7 μg/l would strongly indicate a very poor prognosis. This finding is discussed.

Conclusion

That a use of S 100B as a prognostic tool for clinical decision making is very doubtful and should most probably be refrained from.

Place, publisher, year, edition, pages
2016. Vol. 150, 197-198 p.
Keyword [en]
S 100B, Biomarker, Head injury, Prognosis
National Category
Neurology
Identifiers
URN: urn:nbn:se:umu:diva-129930DOI: 10.1016/j.clineuro.2016.07.026ISI: 000386642300035PubMedID: 27569027OAI: oai:DiVA.org:umu-129930DiVA: diva2:1063810
Available from: 2017-01-11 Created: 2017-01-10 Last updated: 2017-05-10Bibliographically approved

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