Self-Reported General Health among former Nephropathia Epidemica Patients in Northern Sweden.
Independent thesis Advanced level (degree of Master (Two Years)), 10 credits / 15 HE creditsStudent thesis
Background: Nephropathia Epidemica (NE) is a haemorrhagic fever with renal syndrome, caused by Puumala virus. Studies have explored long term outcomes of biomedical importance such as hypertension, renal impairment, risk of lymphoma and hypopuitarism following Puumala Hantavirus infection. However studies of patient-reported outcome in NE are lacking. This study assesses the impact of NE on patient-reported general health.
Methods: 1132 patients serologically diagnosed with NE in Norbotten and Västerbotten counties, from late 2006 – 2011 were compared with a randomly selected comparison group (n=915) from the general population, matched for age, sex and place of residence. Questionnaires were used to collect data about sociodemographic characteristics, disease history, general health, fatigue, sleep and pain. Time since onset of NE ranged between 3 months and >4 years. Difference in SF-36v2 scores between the groups was tested by independent samples t- test. Simple and multiple logistic regression analyses were used to examine association between NE and health status (physical and mental).
Results: Former NE patients had lower mean scores in all 8 domains of the SF 36 and 2 summary measures. Difference between patients and the comparison group was statistically significant in Physical Component Summary (p<0.001) and Mental Component Summary (p=0.017). Furthermore, former NE patients (male and females alike) had a 1.82 times higher odds of poor physical health than the comparison group. Among former NE patients, only females had higher odds of poor mental health. NE was not associated with poor mental health in males.
Conclusions: Former NE patients reported significantly poorer physical health more than 4 years following acute illness, than the comparison group. The impact was found to be greater in females than males. However, among patients, only females reported significantly poorer mental health. No association was observed between NE and poor mental health among former male patients. Future studies preferably longitudinal, would give a clearer picture of the impact of NE on self-reported health, and increase the knowledge base in this area.
Place, publisher, year, edition, pages
2016. , 31 p.
Centre for Public Health Report Series, ISSN 1651-341x ; 2016:35
Nephropathia Epidemica, NE, Northern Sweden
Public Health, Global Health, Social Medicine and Epidemiology
IdentifiersURN: urn:nbn:se:umu:diva-131691OAI: oai:DiVA.org:umu-131691DiVA: diva2:1075299
Västerbottens läns landsting - Maria Furberg
Master's Programme in Public Health
2016-05-23, Umeå Universitet, Umeå, 16:20 (English)
Schumann, Barbara, ResearcherFurberg, Maria, Physician
San Sebastian, Miguel, Professor