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The impact of symptomatic knee osteoarthritis on gait pattern and its association with performance-based measures and patient-reported outcomes
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2017 (English)In: Knee (Oxford), ISSN 0968-0160, E-ISSN 1873-5800Article in journal (Refereed) In press
Abstract [en]

Background

Limited knowledge exists regarding the impact of symptomatic knee osteoarthritis (OA) on the overall gait pattern; and whether gait deviations are associated with performance-based measures (PBMs) and patient-reported outcomes (PROs). This cross-sectional study evaluated overall gait patterns in patients with knee OA using the Gait Deviation Index for kinematics (GDI) and kinetics (GDI-kinetic), and explored associations between gait deviations, PBMs, and PROs.

Methods

Forty patients with knee OA and 25 age and gender-matched controls underwent three-dimensional gait analysis. Participants performed the Timed Up and Go (TUG), Five Times Sit-to-Stand (5STS), and Single Limb Mini Squat (SLMS) tests and completed a disease-specific PRO. Associations between gait deviations, PBMs, and PROs were assessed by Pearson's correlation and multiple linear regression.

Results

Patients with OA demonstrated significantly lower GDI and GDI-kinetic scores of the OA and contralateral limbs compared to controls; with GDI-kinetic scores on the contralateral limb more impacted than the OA limb. On the contralateral limb, GDI-kinetic score significantly correlated with TUG (r = −0.42) and 5STS (r = −0.33), while on the OA limb with TUG (r = −0.68), 5STS (r = −0.38), SLMS (r = −0.38), activities of daily living (r = 0.35) and Knee-related Quality of Life (r = 0.35). No significant associations existed between kinematic GDI scores, PBMs and PROs.

Conclusion

The overall gait pattern, as represented by GDI and GDI-kinetic scores, in patients with symptomatic knee OA is affected both on the painful OA limb and the contralateral limb. The GDI and GDI-kinetic scores provide different information regarding function that is not revealed by PBMs or PROs.

Place, publisher, year, edition, pages
Elsevier, 2017.
Keyword [en]
Gait, Function, Outcome measures, Biomechanics, Osteoarthritis
National Category
Physiotherapy
Research subject
Physiotherapy
Identifiers
URN: urn:nbn:se:umu:diva-132335DOI: 10.1016/j.knee.2017.02.006OAI: oai:DiVA.org:umu-132335DiVA: diva2:1080422
Available from: 2017-03-10 Created: 2017-03-10 Last updated: 2017-03-10

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CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf