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Acute severe depression induced by stimulation of the right globus pallidus internus
Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience, Clinical Neuroscience.
Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience, Clinical Neuroscience.
Umeå University, Faculty of Medicine, Department of Pharmacology and Clinical Neuroscience, Clinical Neuroscience.
2017 (English)In: Neurocase, ISSN 1355-4794, E-ISSN 1465-3656, Vol. 23, no 1, p. 84-87Article in journal (Refereed) Published
Abstract [en]

Depressive symptoms may occur after Deep Brain Stimulation (DBS) in the subthalamic nucleus. This is often explained by reduced pharmacological treatment after surgery, and not as a direct effect of DBS. Pallidal DBS seems not to be associated with such side effects and have not, to our knowledge, previously been reported. We present a patient with acute depressive symptoms induced by pallidal DBS. We believe this case strengthen the hypothesis that the basal ganglia and structures involved in the functional connectome of these nucleuses play a role not only in regulation of movement but also in regulation of mood.

Place, publisher, year, edition, pages
ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD , 2017. Vol. 23, no 1, p. 84-87
Keyword [en]
Deep brain stimulation (DBS), Parkinson's disease, pallidum, basal ganglia, depression
National Category
Neurology
Identifiers
URN: urn:nbn:se:umu:diva-134830DOI: 10.1080/13554794.2017.1284243ISI: 000399644200015PubMedID: 28165911OAI: oai:DiVA.org:umu-134830DiVA, id: diva2:1098328
Available from: 2017-05-24 Created: 2017-05-24 Last updated: 2018-02-06Bibliographically approved

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