umu.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
ICL-based TDLAS sensor for real-time breath gas analysis of carbon monoxide isotopes
Umeå University, Faculty of Science and Technology, Department of Applied Physics and Electronics. (Applied Laser Spectroscopy)
Umeå University, Faculty of Science and Technology, Department of Applied Physics and Electronics. (Applied Laser Spectroscopy, TEC-Lab)ORCID iD: 0000-0002-5065-7786
2017 (English)In: Optics Express, ISSN 1094-4087, E-ISSN 1094-4087, Vol. 25, no 11, 12743-12752 p.Article in journal (Refereed) Published
Abstract [en]

We present a compact sensor for carbon monoxide (CO) in air and exhaled breath based on a room temperature interband cascade laser (ICL) operating at 4.69 µm, a low-volume circular multipass cell and wavelength modulation absorption spectroscopy. A fringe-limited (1σ) sensitivity of 6.5 × 10−8 cm−1Hz-1/2 and a detection limit of 9 ± 5 ppbv at 0.07 s acquisition time are achieved, which constitutes a 25-fold improvement compared to direct absorption spectroscopy. Integration over 10 s increases the precision to 0.6 ppbv. The setup also allows measuring the stable isotope 13CO in breath. We demonstrate quantification of indoor air CO and real-time detection of CO expirograms from healthy non-smokers and a healthy smoker before and after smoking. Isotope ratio analysis indicates depletion of 13CO in breath compared to natural abundance.

Place, publisher, year, edition, pages
Optical Society of America, 2017. Vol. 25, no 11, 12743-12752 p.
Keyword [en]
Laser sensors, Spectroscopy - infrared, Spectroscopy - laser, Biological sensing and sensors, Semiconductor lasers - quantum cascade
National Category
Medical Laboratory and Measurements Technologies Atom and Molecular Physics and Optics Physical Chemistry Physiology
Identifiers
URN: urn:nbn:se:umu:diva-135377DOI: 10.1364/OE.25.012743ISI: 000403940700064OAI: oai:DiVA.org:umu-135377DiVA: diva2:1098658
Available from: 2017-05-24 Created: 2017-05-24 Last updated: 2017-07-20Bibliographically approved

Open Access in DiVA

fulltext(7931 kB)19 downloads
File information
File name FULLTEXT01.pdfFile size 7931 kBChecksum SHA-512
c3747a90d7de063b103a7ac7d84ffdb9d90bfc40275a01c00eeb6f414e434bc1ace7439a4ef38cfaa9d39090394dc1e51f6b5297219981a357a9ba0417a48bab
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Search in DiVA

By author/editor
Ghorbani, RaminSchmidt, Florian M.
By organisation
Department of Applied Physics and Electronics
In the same journal
Optics Express
Medical Laboratory and Measurements TechnologiesAtom and Molecular Physics and OpticsPhysical ChemistryPhysiology

Search outside of DiVA

GoogleGoogle Scholar
Total: 19 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 147 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf